This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-ITGB4 / Integrin Beta 4 Antibody (FITC) LS-C44754
catalog :
LS-C44754
clonality :
monoclonal
host :
rat
conjugate :
FITC
reactivity :
human, mouse
application :
western blot, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
44492
AntibodyName :
LS-C44754
TargetSpecies :
Mouse
Host Species :
Rat
Product Name :
Anti-ITGB4 / Integrin Beta 4 Antibody (FITC) LS-C44754
Specificity :
Recognizes mouse integrin beta 4 (CD104), a 200kD glycoprotein that can associate with integrin alpha 6 (CD49f) to form a heterodimer on the cell surface. Expression of CD104 is localized to the basal region of a wide variety of epithelial cells. In mice, CD104 is also expressed on peripheral neurons, carcinoma cell lines and a subset of endothelial cells. The alpha 6 beta 4 (CD49f/CD104) integrin has been identified as a component of hemidesmosomes in stratified squamous epithelium where it plays an important role in the adhesion of epithelia to basement membrane. Studies suggest that the CD49f/CD104 integrin is involved in cell matrix adhesion but expression of the CD49f/CD104 integrin in endothelial cells is thought to have a different function.
ClonalityDesc :
Monoclonal
AntibodyModification :
FITC
PresentationDesc :
PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
ImmunogenDesc :
TSP-180 purified from Balb/c murine carcinoma.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
IsotypeName :
IgG2a
Gene :
ITGB4 / Integrin Beta 4
StandardGeneSymbol :
ITGB4
gene family :
Integrin
Reactivity :
Mouse
Usage :
Flo (1:1 - 1:5), IHC-Fr, IP, WB
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul Method sheets are available on request.
Synonyms :
ITGB4, CD104, Integrin beta-4, Integrin Beta 4, gp150, CD104 antigen, Integrin beta-4 subunit, Integrin, beta 4
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.