This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
DIABLO / SMAC Antibody (C-Terminus) LS-C42866
catalog :
LS-C42866
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
42604
AntibodyName :
LS-C42866
TargetSpecies :
Mouse
Host Species :
Rabbit
Product Name :
DIABLO / SMAC Antibody (C-Terminus) LS-C42866
Specificity :
Recognizes Diablo homolog, mitochondrial, also known as Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase, Diablo or Smac. Smac is a 237 amino acid ~30 kD mitochondrial protein bearing a 53 amino acid transit peptide at its N-terminus. Binds to the C-terminal region of murine Smac/DIABLO. Inhibitors of apoptosis proteins (IAP's) block cell death by caspase inhibition. X-linked inhibitor of apoptosis (XIAP) is a member of the IAP family. Smac/DIABLO is expressed in a variety of tissues and has been identified as a negative regulator of XIAP.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
PBS, 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to amino acids 222-237 of mouse Smac/DIABLO (C-TERMINAL).
PurificationDesc :
Purified
IsotypeName :
IgG
Gene :
DIABLO / SMAC
StandardGeneSymbol :
DIABLO
gene family :
Apoptosis
Reactivity :
Mouse, Rat, Human
Usage :
IHC, IHC-P, WB (1 µg/ml)
ShortWebDescription :
SMAC antibody LS-C42866 is an unconjugated rabbit polyclonal antibody to SMAC (DIABLO ) from human, mouse and rat. Validated for IHC and WB.
UsageText :
Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.
Synonyms :
DIABLO, DFNA64, DIABLO-S, Diablo homolog, mitochondrial, SMAC3, Mitochondrial Smac protein, SMAC
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.