This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-NALP3 / NLRP3 Antibody (aa1024-1036) IHC-plus™ LS-B1766
catalog :
LS-B1766
quantity :
50 µg
price :
395 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, rat
application :
immunohistochemistry - paraffin section
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; rat; 1:200
Kono S, Kurata T, Sato K, Omote Y, Hishikawa N, Yamashita T, et al. Neurovascular protection by telmisartan via reducing neuroinflammation in stroke-resistant spontaneously hypertensive rat brain after ischemic stroke. J Stroke Cerebrovasc Dis. 2015;24:537-47 pubmed publisher
product information
AntibodyID :
48129
AntibodyName :
LS-B1766
TargetSpecies :
Human
Host Species :
Goat
Product Name :
Anti-NALP3 / NLRP3 Antibody (aa1024-1036) IHC-plus™ LS-B1766
Specificity :
Human NLRP3. Variants (NP_001073289.1; NP_004886.3) encode the same isoform.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa1024-1036
PresentationDesc :
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide C-EKPELTVVFEPSW from the C-terminus of human NLRP3 (NP_001073289.1; NP_004886.3; NP_899632.1; NP_001120933.1; NP_001120934.1). Percent identity by BLAST analysis: Human, Gibbon (100%); Monkey, Marmoset, Rat, Rabbit, Horse (92%); Mouse, Bovine, Panda (85%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Store at -20°C. Avoid freeze-thaw cycles.
Gene :
NALP3 / NLRP3
StandardGeneSymbol :
NLRP3
Reactivity :
Human
Usage :
ELISA (1:32000), IHC-P (2.5 µg/ml)
UsageText :
Immunohistochemistry: LS-B1766 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1766 was determined to be 2.5 ug/ml.
Synonyms :
NLRP3, AGTAVPRL, AII, C1orf7, Caterpiller protein 1.1, Cryopyrin, FCAS, FCU, PYPAF1, NALP3, CIAS1, CLR1.1, MWS
ProductID :
57580
ProductNumber :
LS-B1766-50
Weight :
50 µg
Concentration :
0.5 mg/ml
LSListPrice :
395 USD
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.