ERK1/ERK2 Polyclonal Antibody | Invitrogen 61-7400 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ERK1/ERK2 Polyclonal Antibody

catalog :

61-7400

quantity :

100µg

price :

US 309.00

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

African green monkey, human, mouse, rat, rabbit

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 3b	Yong K, Li A, Ou W, Hong C, Zhao W, Wang F, et al. Targeting SALL4 by entinostat in lung cancer. Oncotarget. 2016;7:75425-75440 pubmed publisher
western blot; African green monkey; loading ...; fig 5c	Makita N, Sato T, Yajima-Shoji Y, Sato J, Manaka K, Eda-Hashimoto M, et al. Analysis of the V2 Vasopressin Receptor (V2R) Mutations Causing Partial Nephrogenic Diabetes Insipidus Highlights a Sustainable Signaling by a Non-peptide V2R Agonist. J Biol Chem. 2016;291:22460-22471 pubmed
western blot; mouse; 1:5000; loading ...; fig 5	Hernandez R, Puro A, Manos J, Huitron-Resendiz S, Reyes K, Liu K, et al. Transgenic mice with increased astrocyte expression of IL-6 show altered effects of acute ethanol on synaptic function. Neuropharmacology. 2016;103:27-43 pubmed publisher
western blot; human	Majuelos-Melguizo J, Rodriguez M, López-Jiménez L, Rodríguez-Vargas J, Martí Martín-Consuegra J, Serrano-Sáenz S, et al. PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma. Oncotarget. 2015;6:4790-803 pubmed
immunohistochemistry - paraffin section; human; 1:100; fig 3	Riemenschneider M, Mueller W, Betensky R, Mohapatra G, Louis D. In situ analysis of integrin and growth factor receptor signaling pathways in human glioblastomas suggests overlapping relationships with focal adhesion kinase activation. Am J Pathol. 2005;167:1379-87 pubmed
western blot; mouse; fig 4	Gruol D, Puro A, Hao C, Blakely P, Janneke E, Vo K. Neuroadaptive changes in cerebellar neurons induced by chronic exposure to IL-6. J Neuroimmunol. 2011;239:28-36 pubmed publisher
western blot; mouse; 1:5000; fig 2	Gruol D, Vo K, Bray J. Increased astrocyte expression of IL-6 or CCL2 in transgenic mice alters levels of hippocampal and cerebellar proteins. Front Cell Neurosci. 2014;8:234 pubmed publisher
western blot; mouse; 1:5000	Gruol D, Vo K, Bray J, Roberts A. CCL2-ethanol interactions and hippocampal synaptic protein expression in a transgenic mouse model. Front Integr Neurosci. 2014;8:29 pubmed publisher
western blot; mouse	Auger R, Motta I, Benihoud K, Ojcius D, Kanellopoulos J. A role for mitogen-activated protein kinase(Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death. J Biol Chem. 2005;280:28142-51 pubmed
western blot; mouse; fig 2	Lefloch R, Pouyssegur J, Lenormand P. Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels. Mol Cell Biol. 2008;28:511-27 pubmed
western blot; mouse	Guo J, Wang H, Malbon C. Conditional, tissue-specific expression of Q205L Galphai2 in vivo mimics insulin activation of c-Jun N-terminal kinase and p38 kinase. J Biol Chem. 1998;273:16487-93 pubmed
western blot; human	Lee J, Kang M, Jang S, Qian T, Kim H, Kim C, et al. Id-1 activates Akt-mediated Wnt signaling and p27(Kip1) phosphorylation through PTEN inhibition. Oncogene. 2009;28:824-31 pubmed publisher
immunocytochemistry; rat; fig 5a	Bajova H, Nelson T, Gruol D. Chronic CXCL10 alters the level of activated ERK1/2 and transcriptional factors CREB and NF-kappaB in hippocampal neuronal cell culture. J Neuroimmunol. 2008;195:36-46 pubmed publisher
western blot; rat	Lamprecht M, Morrison B. GPR30 activation is neither necessary nor sufficient for acute neuroprotection by 17β-estradiol after an ischemic injury in organotypic hippocampal slice cultures. Brain Res. 2014;1563:131-7 pubmed publisher
	Wehenkel M, Corr M, Guy C, Edwards B, Castellaw A, Calabrese C, et al. Extracellular Signal-Regulated Kinase Signaling in CD4-Expressing Cells Inhibits Osteochondromas.. Front Immunol. 2017;8:482 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ERK1/ERK2 Polyclonal Antibody

Catalog # :

61-7400

Quantity :

100µg

Price :

US 309.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rabbit, Rat

Applications :

ELISA: Assay Dependent, Immunocytochemistry: 2 µg/ml, Immunofluorescence: 2 µg/ml, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Rabbit, Rat

Isotype :

IgG

Storage :

-20°C

Description :

Extracellular signal-regulated kinase 2 (Erk2) is also known as mitogen activated protein kinase 2, microtubule-associated protein-2 kinase MAP kinase 2, p42-MAPK or EGF receptor T669 (ERT1). Mek2 activates Erk2 by phosphorylation of neighbouring threonine-183 and tyrosine-185 residues. Erk2, a serine-threonine kinase phosphorylates microtubule associated protein-2 and myelin basic protein. This kinase is an important proximal componant of the MAP kinase pathway involved in transmitting the signals from growth factors, neurotransmitters and hormones at the cell surface to the transcriptional events in the nucleus.

Immunogen :

Synthetic peptide (a.a. 339-353) corresponding to a C-terminal segment of rat ERK1

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay Dependent, Immunocytochemistry: 2 µg/ml, Immunofluorescence: 2 µg/ml, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1:500-1:2,000

Aliases :

ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, MAPK, Mitogen activated protein kinase, ERK1, p42, Mitogen activated protein kinase 1, Mitogen activated protein kinase 2, p42 MAP Kinase, p44 MAP Kinase

PubMed References :

15937334, 16251422, 17967895, 18329727, 19079342, 21890220, 24704272, 24772072, 25177271, 25576921, 26707655, 27601473, 27705911, 28507546, 9632716

more info or order :

Invitrogen product webpage