EZH2 Polyclonal Antibody | Invitrogen 49-1043 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EZH2 Polyclonal Antibody

catalog :

49-1043

quantity :

50µg

price :

US 309.00

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, chromatin immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:50	Hung S, Lin H, Yeh K, Chang J. Histone-modifying genes as biomarkers in hepatocellular carcinoma. Int J Clin Exp Pathol. 2014;7:2496-507 pubmed
chromatin immunoprecipitation; human western blot; human; 1:1000	Cao Q, Wang X, Zhao M, Yang R, Malik R, Qiao Y, et al. The central role of EED in the orchestration of polycomb group complexes. Nat Commun. 2014;5:3127 pubmed publisher
chromatin immunoprecipitation; human	Wu L, Runkle C, Jin H, Li J, Yang X, Kuzel T, et al. CCN3/NOV gene expression in human prostate cancer is directly suppressed by the androgen receptor. Oncogene. 2014;33:504-13 pubmed publisher
	Alajez N, Shi W, Hui A, Bruce J, Lenarduzzi M, Ito E, et al. Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98. Cell Death Dis. 2010;1:e85 pubmed publisher
	Guo J, Cai J, Yu L, Tang H, Chen C, Wang Z. EZH2 regulates expression of p57 and contributes to progression of ovarian cancer in vitro and in vivo. Cancer Sci. 2011;102:530-9 pubmed publisher

product information

Product Type :

Antibody

Product Name :

EZH2 Polyclonal Antibody

Catalog # :

49-1043

Quantity :

50µg

Price :

US 309.00

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

ChIP assay: Assay Dependent, Western Blot: Assay Dependent

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Mutations affecting EZH2 can cause Weaver syndrome (WVS).

Immunogen :

N-terminus (aa1-343) of the mouse Ezh2 protein

Format :

Liquid

Applications w/Dilutions :

ChIP assay: Assay Dependent, Western Blot: Assay Dependent

Aliases :

EZH2, KMT6, Histone-lysine N-methyltransferase EZH2, ENX-1, Enhancer of zeste homolog 2, Lysine N-methyltransferase 6

more info or order :

Invitrogen product webpage