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antibody

Tri-Methyl-Histone H4 (Lys20) Polyclonal Antibody

49-1024

100µL

US 325.00

polyclonal

rabbit

nonconjugated

western blot, ELISA

Tri-Methyl-Histone H4 (Lys20) Polyclonal Antibody

49-1024

100µL

US 325.00

Polyclonal

Rabbit

Human

ChIP assay: 1:100, ELISA: 1:700, Western Blot: 1:750

Human

IgG

-20° C, Avoid Freeze/Thaw Cycles

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element.

Raised against the region of the histone H4 containing the trimethylated lysine 20 (or [K20me3]), using a KLH-conjugated synthetic peptide.

Liquid

ChIP assay: 1:100, ELISA: 1:700, Western Blot: 1:750

H3K20me3, Histone H3, Histone 1, H3a, Histone H3.1, histone H3/a, HIST1H3A