Nonphospho-EGFR (Tyr1173) Monoclonal Antibody (20G3) | Invitrogen 44794M product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Nonphospho-EGFR (Tyr1173) Monoclonal Antibody (20G3)

catalog :

44794M

quantity :

50µL

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

20G3

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:200	Chung C, Parker J, Karaca G, Wu J, Funkhouser W, Moore D, et al. Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression. Cancer Cell. 2004;5:489-500 pubmed

product information

Product Type :

Antibody

Product Name :

Nonphospho-EGFR (Tyr1173) Monoclonal Antibody (20G3)

Catalog # :

44794M

Quantity :

50µL

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Size-exclusion chromatography

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

ELISA: Assay Dependent, Immunocytochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Species :

Human, Mouse

Clone :

20G3

Isotype :

IgG1

Storage :

-80°C

Description :

Epidermal Growth Factor Receptor (EGFR) is a 175 kDa transmembrane glycoprotein belonging to tyrosine kinase superfamily. It acts as a receptor for epidermal growth factor (EGF) family proteins. Binding of EGFR to its ligands causes autophosphorylation of tyrosine kinase followed by activation of signal transduction pathways connected to cell proliferation and differentiation. Tyrosine 1068 present within the cytoplasmic domain of the receptor is a major autophosphorylation site that allows binding of Grb2 and activation of the Ras-Raf-ERK1 and ERK2 signaling pathway.

Immunogen :

Synthetic peptide derived from the region of EGFR containing tyrosine 1173 (dephosphorylated), conjugated to KLH.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay Dependent, Immunocytochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Aliases :

EC 2.7.10.1, ERBB1, Epidermal growth factor receptor precursor, Receptor protein-tyrosine kinase ErbB-1, kinase EGFR

PubMed References :

15144956