Phospho-SRC (Tyr529) Polyclonal Antibody | Invitrogen 44-662G product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-SRC (Tyr529) Polyclonal Antibody

catalog :

44-662G

quantity :

10 blots

price :

US 309.00

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse, rat, chicken

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; rat	Peckham H, Giuffrida L, Wood R, Gonsalvez D, Ferner A, Kilpatrick T, et al. Fyn is an intermediate kinase that BDNF utilizes to promote oligodendrocyte myelination. Glia. 2016;64:255-69 pubmed publisher
western blot; rat; 1:1000; loading ...; fig 4a	Wang Y, Han G, Guo B, Huang J. Hyaluronan oligosaccharides promote diabetic wound healing by increasing angiogenesis. Pharmacol Rep. 2016;68:1126-1132 pubmed publisher
immunoprecipitation; human western blot; human	Thapa N, Choi S, Hedman A, Tan X, Anderson R. Phosphatidylinositol phosphate 5-kinase Iγi2 in association with Src controls anchorage-independent growth of tumor cells. J Biol Chem. 2013;288:34707-18 pubmed publisher
	Bernard-Trifilo J, Lim S, Hou S, Schlaepfer D, Ilic D. Analyzing FAK and Pyk2 in early integrin signaling events. Curr Protoc Cell Biol. 2006;0:Unit 14.7 pubmed publisher
	Lau K, Stiffel V, Amoui M. An osteoclastic protein-tyrosine phosphatase regulates the β3-integrin, syk, and shp1 signaling through respective src-dependent phosphorylation in osteoclasts. Am J Physiol Cell Physiol. 2012;302:C1676-86 pubmed publisher
	Tzima E, Irani-Tehrani M, Kiosses W, Dejana E, Schultz D, Engelhardt B, et al. A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature. 2005;437:426-31 pubmed
	Bock H, Herz J. Reelin activates SRC family tyrosine kinases in neurons. Curr Biol. 2003;13:18-26 pubmed

product information

Product Type :

Antibody

Product Name :

Phospho-SRC (Tyr529) Polyclonal Antibody

Catalog # :

44-662G

Quantity :

10 blots

Price :

US 309.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Chicken, Human, Mouse, Rat

Applications :

Immunocytochemistry: 1 µg/ml, Immunofluorescence: 1 µg/ml, Immunohistochemistry (Paraffin): 1:50-1:500, Western Blot: 1-2 µg/mL

Species :

Chicken, Human, Mouse, Rat

Isotype :

IgG

Storage :

-20°C

Description :

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. Transcript Variant: This variant (1) represents the longer transcript. Both isoforms 1 and 2 encode the same protein.

Immunogen :

The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human Src that contains tyrosine 529 (tyrosine 530 including the initiating methionine). The sequence is conserved in mouse, rat, chicken and frog.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1 µg/ml, Immunofluorescence: 1 µg/ml, Immunohistochemistry (Paraffin): 1:50-1:500, Western Blot: 1-2 µg/mL

Aliases :

EC 2.7.10.2, p60-Src, c-Src, pp60c-src

PubMed References :

12526740, 16163360, 18228476, 22460711, 24151076, 26449489, 27588388

more info or order :

Invitrogen product webpage