BMI-1 Monoclonal Antibody (1H6B10G7) | Invitrogen 37-5400 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

BMI-1 Monoclonal Antibody (1H6B10G7)

catalog :

37-5400

quantity :

100µg

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1H6B10G7

reactivity :

human

application :

western blot, ELISA, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human; fig 2a western blot; human; loading ...; fig 2a	Banerjee Mustafi S, Chakraborty P, Dwivedi S, Ding K, Moxley K, Mukherjee P, et al. BMI1, a new target of CK2?. Mol Cancer. 2017;16:56 pubmed publisher
western blot; human; fig 1	Dey A, Mustafi S, Saha S, Kumar Dhar Dwivedi S, Mukherjee P, Bhattacharya R. Inhibition of BMI1 induces autophagy-mediated necroptosis. Autophagy. 2016;12:659-70 pubmed publisher
western blot; human	Datta S, Hoenerhoff M, Bommi P, Sainger R, Guo W, Dimri M, et al. Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways. Cancer Res. 2007;67:10286-95 pubmed
western blot; human	Guo W, Zeng M, Yadav A, Song L, Guo B, Band V, et al. Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and down-regulating Akt activity in breast cancer cells. Cancer Res. 2007;67:5083-9 pubmed
western blot; human; fig 3	Jiang R, Xu W, Zhu W, Chen M, Qian H, Qiao C, et al. Histological type of oncogenity and expression of cell cycle genes in tumor cells from human mesenchymal stem cells. Oncol Rep. 2006;16:1021-8 pubmed
	Bhattacharya R, Kwon J, Ali B, Wang E, Patra S, Shridhar V, et al. Role of hedgehog signaling in ovarian cancer. Clin Cancer Res. 2008;14:7659-66 pubmed publisher

product information

Product Type :

Antibody

Product Name :

BMI-1 Monoclonal Antibody (1H6B10G7)

Catalog # :

37-5400

Quantity :

100µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay Dependent, Western Blot: Assay Dependent

Species :

Human

Clone :

1H6B10G7

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Immunogen :

Synthetic peptide derived from the mid region of the human Bim-1 protein.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay Dependent, Western Blot: Assay Dependent

Aliases :

BMI1, PCGF4, RNF51, Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51

more info or order :

Invitrogen product webpage