WNT1 Polyclonal Antibody | Invitrogen 36-5800 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

WNT1 Polyclonal Antibody

catalog :

36-5800

quantity :

100µg

price :

US 309.00

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, Rhesus monkey

application :

western blot, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 4	Shi C, Zhang M, Tong M, Yang L, Pang L, Chen L, et al. miR-148a is Associated with Obesity and Modulates Adipocyte Differentiation of Mesenchymal Stem Cells through Wnt Signaling. Sci Rep. 2015;5:9930 pubmed publisher
western blot; rat; fig 1	Kim W, Lewis C, McCall K, Malgor R, Kohn A, Moon R, et al. Overexpression of Wnt-1 in thyrocytes enhances cellular growth but suppresses transcription of the thyroperoxidase gene via different signaling mechanisms. J Endocrinol. 2007;193:93-106 pubmed
	Liu W, Rui H, Wang J, Lin S, He Y, Chen M, et al. Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia. EMBO J. 2006;25:1646-58 pubmed

product information

Product Type :

Antibody

Product Name :

WNT1 Polyclonal Antibody

Catalog # :

36-5800

Quantity :

100µg

Price :

US 309.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rhesus Monkey

Applications :

Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Species :

Human, Mouse, Rhesus Monkey

Isotype :

IgG

Storage :

-20°C

Description :

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.

Immunogen :

Synthetic peptide derived from the C-terminal region of the human WNT1 protein.

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Aliases :

INT1, proto-oncogene Int-1 homolog, proto-oncogene Wnt-1, wingless-type MMTV integration site family, member 1 oncogene INT1, Wnt-1

PubMed References :

16601693, 17400807, 26001136

more info or order :

Invitrogen product webpage