gamma Catenin Monoclonal Antibody (PG-11E4) | Invitrogen 13-8500 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

gamma Catenin Monoclonal Antibody (PG-11E4)

catalog :

13-8500

quantity :

100µg

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PG-11E4

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; fig 6	Val S, Burgett K, Brown K, Preciado D. SuperSILAC Quantitative Proteome Profiling of Murine Middle Ear Epithelial Cell Remodeling with NTHi. PLoS ONE. 2016;11:e0148612 pubmed publisher
immunocytochemistry; mouse; 1:500; fig 3a western blot; mouse; 1:1000; fig 3b	Lombardi R, Chen S, Ruggiero A, Gurha P, Czernuszewicz G, Willerson J, et al. Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene. Circ Res. 2016;119:41-54 pubmed publisher
immunohistochemistry; human; 1:150; fig 1	Wex T, Kuester D, Monkemuller K, Stahr A, Fry L, Kandulski A, et al. Assessment of desmosomal components (desmoglein 1-3, plakoglobin) in cardia mucosa in relation to gastroesophageal reflux disease and Helicobacter pylori infection. Hum Pathol. 2012;43:1745-54 pubmed publisher
western blot; mouse	Grooteclaes M, Deveraux Q, Hildebrand J, Zhang Q, Goodman R, Frisch S. C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs. Proc Natl Acad Sci U S A. 2003;100:4568-73 pubmed
immunohistochemistry; human; 1:150; fig 1	Wex T, Monkemuller K, Stahr A, Kuester D, Fry L, Völkel S, et al. Gastro-oesophageal reflux disease is associated with up-regulation of desmosomal components in oesophageal mucosa. Histopathology. 2012;60:405-15 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:300	Lei Z, Maeda T, Tamura A, Nakamura T, Yamazaki Y, Shiratori H, et al. EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins. Dev Biol. 2012;371:136-45 pubmed publisher
western blot; human; fig 3	Luber B, Candidus S, Handschuh G, Mentele E, Hutzler P, Feller S, et al. Tumor-derived mutated E-cadherin influences beta-catenin localization and increases susceptibility to actin cytoskeletal changes induced by pervanadate. Cell Adhes Commun. 2000;7:391-408 pubmed
immunocytochemistry; human; fig 4	Akat K, Bleck C, Lee Y, Haselmann-Weiss U, Kartenbeck J. Characterization of a novel type of adherens junction in meningiomas and the derived cell line HBL-52. Cell Tissue Res. 2008;331:401-12 pubmed
immunocytochemistry; human western blot; human	Law M, Corsino P, Jahn S, Davis B, Chen S, Patel B, et al. Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms. Oncogene. 2013;32:1316-29 pubmed publisher
immunocytochemistry; mouse; fig 4 western blot; mouse	Kim Y, Sauer C, Testa K, Wahl J, Svoboda R, Johnson K, et al. Modulating the strength of cadherin adhesion: evidence for a novel adhesion complex. J Cell Sci. 2005;118:3883-94 pubmed
immunoprecipitation; rat; tbl 1 western blot; rat; tbl 1	Sarkar O, Xia W, Mruk D. Adjudin-mediated junction restructuring in the seminiferous epithelium leads to displacement of soluble guanylate cyclase from adherens junctions. J Cell Physiol. 2006;208:175-87 pubmed
western blot; human	Jeannet G, Scheller M, Scarpellino L, Duboux S, Gardiol N, Back J, et al. Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. Blood. 2008;111:142-9 pubmed
immunoprecipitation; human; fig 1	Lai Y, Cheng J, Cheng D, Feasel M, Beste K, Peng J, et al. SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells. BMC Cell Biol. 2011;12:50 pubmed publisher
	Descargues P, Deraison C, Bonnart C, Kreft M, Kishibe M, Ishida-Yamamoto A, et al. Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity. Nat Genet. 2005;37:56-65 pubmed
	Kaplan D, Meigs T, Kelly P, Casey P. Identification of a role for beta-catenin in the establishment of a bipolar mitotic spindle. J Biol Chem. 2004;279:10829-32 pubmed
	Silberberg M, Charron A, Bacallao R, Wandinger-Ness A. Mispolarization of desmosomal proteins and altered intercellular adhesion in autosomal dominant polycystic kidney disease. Am J Physiol Renal Physiol. 2005;288:F1153-63 pubmed

product information

Product Type :

Antibody

Product Name :

gamma Catenin Monoclonal Antibody (PG-11E4)

Catalog # :

13-8500

Quantity :

100µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1:250

Species :

Human, Mouse

Clone :

PG-11E4

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

JUP is a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.

Immunogen :

Fusion protein consisting of the maltose binding protein fused to full length human plakoglobin protein.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1:250

Aliases :

JUP, CTNNG, DP3, Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3

PubMed References :

10830618, 12676992, 14744872, 15619623, 15701820, 16091424, 16547975, 17906078, 17965884, 22098624, 22276604, 22521077, 22543582, 22819673, 26859300, 27121621

more info or order :

Invitrogen product webpage