Mouse AntiNestin | ImmuQuest IQ301 product information

product summary

request information :

company name :

ImmuQuest

product type :

antibody

product name :

Mouse AntiNestin

catalog :

IQ301

quantity :

0.2 ml

price :

299 USD

clonality :

monoclonal

host :

mouse

reactivity :

human

application :

western blot, FACS, immunoprecipitation, immunohistochemistry, immunocytochemistry

more info or order :

ImmuQuest product webpage

product information

Target Antigen :

Nestin

Primary Description :

Mouse AntiNestin

Catalgoue Number :

IQ301

quantity :

0.2 ml

Clone :

2C1.3A11

Host/Isotype :

Mouse IgG1

Immunogen :

A 150-amino-acid fragment from the cloned human nestin conjugated to GST

Specificity :

Human nestin with no cross- reactivity to rodent ;

Purification :

Protein G

Format :

Purified antibody containing PBS 0.1% sodium azide;

Applications :

FACS; IB; ICC; IHC (P); IP;

Dilutions :

Optimal antibody dilution should be determined by titration, however as a guideline try at 1:1000-1:5000 for western blot 1:100-1:500 for immuncytochemistry. Additional antigen retrieval may be necessary depending on fixation method.

Relevance :

Nestin is a Class VI intermediate filament expressed in the developing central nervous system (CNS) in early embryonic neuroepithelial stem cells. This protein has been widely used as a predominant marker for stem / progenitor cells, glioma cells, and tumor endothelial cells in the mammalian CNS. Furthermore, it is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumor. This highly specific antibody to human nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells.

References :

Coexpression of nestin in neural and glial cells in the developing human CNS defined by a humanspecific antinestin antibody. Messam CA ( Exp Neurol,Feb 2000)

Research areas :

Angiogenic Factors; Intermediate Filaments; Intracellular; Neuronal Markers; Neuroscience;

Also known as :

ESTM 46 antibody;FLJ 21841 antibody;FLJ21841 antibody;Intermediate filament proteinantibody;Nbla00170 antibody;Nes antibody;NEST_HUMAN antibody;Nestin antibody

Price (Pounds) :

226

Price (Dollars) :

299 USD

Price (Euros) :

338

more info or order :

ImmuQuest product webpage