BRCA2 antibody [3E6] | GeneTex GTX70121 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

BRCA2 antibody [3E6]

catalog :

GTX70121

quantity :

100.00μg

price :

299 USD

clonality :

monoclonal

host :

mouse

clone name :

3E6

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 4

Published Application/Species/Dilution	Reference
	Bernard-Gallon D, Dechelotte P, Le Corre L, Chalabi N, Vissac-Sabatier C, Bignon Y. Differential expressions of BRCA1 and BRCA2 in infantile gynecomastia. Anticancer Res. 2004;24:321-4 pubmed
	Edwards S, Brough R, Lord C, Natrajan R, Vatcheva R, Levine D, et al. Resistance to therapy caused by intragenic deletion in BRCA2. Nature. 2008;451:1111-5 pubmed publisher
	Shin S, Verma I. BRCA2 cooperates with histone acetyltransferases in androgen receptor-mediated transcription. Proc Natl Acad Sci U S A. 2003;100:7201-6 pubmed
	Bernard-Gallon D, Vissac C, Aunoble B, Cravello L, Malpuech G, Bignon Y. BRCA1 and BRCA2 protein expressions in an ovotestis of a 46, XX true hermaphrodite. Breast Cancer Res. 2001;3:61-5 pubmed

product information

Catalog No :

GTX70121

Product Name :

BRCA2 antibody [3E6]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μg

List Price :

299 USD

list of Pubmed id :

12756300,15015615,11250747,18264088

Clone :

3E6

Isotype :

IgG1

Product Description :

BRCA2 antibody mouse monoclonal [3E6]

CrossReactivity :

Background :

The BRCA2 antibody clone 3E6 recognizes the BRCA2 gene product, a 390kDa nuclear protein. The BRCA2 gene was originally isolated based on its importance in the predisposition of women to early-onset breast and ovarian cancers, suggesting mutations affect its tumor suppressor-like activity. Targeted disruption of the BRCA2 gene in mice and binding of Rad51 to its carboxyl terminus have indicated an involvement in DNA recombination and double strand break repair.

Immunogen :

Amino acids 188-563 of human BRCA2 expressed in E. coli. BRCA2-BBA.

Specificity :

This antibody recognizes the BRCA2 gene product, a 390-kDa nuclear protein.

Buffer :

Phosphate-buffered saline, pH 7.2, no preservative added.

Uses :

ICC/IF, IHC, IP, WB

Concentration :

1mg/ml

General References :

For long term storage, please keep at -70 °C or below. Avoid repeated freeze-thaw cycles.