TERT antibody [2C4] | GeneTex GTX30410 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

TERT antibody [2C4]

catalog :

GTX30410

quantity :

100.00μl

price :

299 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2C4

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, FACS, immunohistochemistry - paraffin section

citations: 3

Reference
Schauer I, Zhang J, Xing Z, Guo X, Mercado-Uribe I, Sood A, et al. Interleukin-1β promotes ovarian tumorigenesis through a p53/NF-κB-mediated inflammatory response in stromal fibroblasts. Neoplasia. 2013;15:409-20 pubmed
Liu S, Qi Y, Ge Y, Duplessis T, Rowan B, Ip C, et al. Telomerase as an important target of androgen signaling blockade for prostate cancer treatment. Mol Cancer Ther. 2010;9:2016-25 pubmed publisher
Aras G, Kanmaz D, Urer N, Purisa S, Kadakal F, Yenturk E, et al. Immunohistochemical expression of telomerase in patients with non-small cell lung cancer: prediction of metastasis and prognostic significance. Anticancer Res. 2013;33:2643-50 pubmed

product information

Catalog No :

GTX30410

Product Name :

TERT antibody [2C4]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μl

List Price :

299 USD

list of Pubmed id :

20571066,23749922,23555186

Clone :

2C4

Isotype :

IgM

Product Description :

Mouse monoclonal [2C4] to Human telomerase reverse transcriptase (hTERT)

CrossReactivity :

Background :

Telomeres are nucleoprotein structures at the ends of eukaryotic chromosomes. They regulate several crucial cellular functions and participate in the control of complex phenotypes, such as aging and cancer. Cell immortalization is strongly associated with the stabilization of telomere length. Therefore, it is suggested that cancer cells achieve immortalization in part through illegitimate activation of telomerase expression. hTERT is the rate-limiting catalytic subunit of telomerase.

Immunogen :

Recombinant full length protein (Human) from insect cells.

Specificity :

Is specific for hTERT(1).

Buffer :

100 µl of mouse ascites in Phosphate-buffered saline containing 0.1% sodium azide

Uses :

FACS, ICC/IF, IHC, IHC-P, WB, WB-Ag

General References :

Upon Receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

Image Legend_4 :

Flow Cytometry: Telomerase reverse transcriptase Antibody (2C4) [GTX30410] - Staining of NTERA-2 cells using GTX30410 at a 1:200 dilution detected using Dylight-488 conjugated goat anti-mouse IgM secondary antibody.

Image Legend_5 :

Immunocytochemistry/Immunofluorescence: Telomerase reverse transcriptase Antibody (2C4) [GTX30410] - Detection of Tert (Green) in HepG2 cells using GTX30410. Nuclei (Blue) are counterstained with Hoechst 33258

Image Legend_6 :

Western Blot: Telomerase reverse transcriptase Antibody (2C4) [GTX30410] - 1:500 dilution on MJ90 cells.