This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
PKR (phospho Thr451) antibody
catalog :
GTX24818
quantity :
50.00μl
price :
289 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse
application :
western blot
product information
Catalog No :
GTX24818
Product Name :
PKR (phospho Thr451) antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Antigen Modification :
Phosphorylated
Product Type :
Primary antibody
Size :
50.00μl
List Price :
289 USD
Isotype :
IgG
Product Description :
Rabbit polyclonal to PKR (phospho T451)
CrossReactivity :
Hu, Ms
Background :
PKR is an interferon-inducible serine/threonine-specific proteinkinase. It is widely expressed in eukaryotic organisms and activated by double-stranded RNA. The activation of PKR is accompanied by autophosphorylation at multiple sites. Phosphorylation of Thr446 and Thr451 in the PKR activation loop is required in vivo and in vitro for high-level kinase activity. PKR phosphorylates the alpha subunit of eukaryotic initiation factor 2 and inhibits protein synthesis. It is an important component of the interferon response to virus infection. Recently, it has been reported that PKR also phosphorylates human p53 on serine 392.
Immunogen :
Synthetic peptide derived from the region of PKR that contains threonine451. The sequence was aligned to human.
Specificity :
Phosphorylation site-specific antibody selective for the phosphorylated form of the PKR (double-stranded RNA-dependent protein kinase) protein containing a phosphate on threonine 451. This antibody recognizes a protein of 65-68 kDa resolved by SDS-PAGE, identified as PKR.
Buffer :
Preservative: 0.05% Sodium Azide; Constituents: PBS, 50% glycerol, 1mg/ml BSA (IgG, protease free). pH 7.3
Uses :
WB
General References :
Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
company information
GeneTex
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