This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
SMAD4 antibody
catalog :
GTX112980
quantity :
100.00μl
price :
299 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
product information
Catalog No :
GTX112980
Product Name :
SMAD4 antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Product Type :
Primary antibody
Size :
100.00μl
List Price :
299 USD
Isotype :
IgG
Product Description :
Rabbit Polyclonal antibody to SMAD4 (mothers against decapentaplegic homolog 4)
CrossReactivity :
Hu, Ms, Rat
Background :
This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq]
Immunogen :
Recombinant protein encompassing a sequence within the C-terminus region of human SMAD4. The exact sequence is proprietary.
Buffer :
1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Uses :
ICC/IF, IHC-P, WB
Concentration :
1.41mg/ml
General References :
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Image Legend_4 :
Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 (GTX27900) 7.5% SDS PAGE GTX112980 diluted at 1:1000
Image Legend_5 :
SMAD4 antibody detects SMAD4 protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with SMAD4 antibody (GTX112980) diluted by 1:1000.
Image Legend_6 :
SMAD4 antibody detects SMAD4 protein by western blot analysis. A. 30 μg PC-12 whole cell extract . 7.5 % SDS-PAGE. SMAD4 antibody (GTX112980) dilution: 1:1000
company information
GeneTex
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