CDK4 antibody | GeneTex GTX102993 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

CDK4 antibody

catalog :

GTX102993

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 3c	LI Y, Du L, Aldana Masangkay G, Wang X, Urak R, Forman S, et al. Regulation of miR-34b/c-targeted gene expression program by SUMOylation. Nucleic Acids Res. 2018;: pubmed publisher
	Amulic B, Knackstedt S, Abu Abed U, Deigendesch N, Harbort C, Caffrey B, et al. Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps. Dev Cell. 2017;43:449-462.e5 pubmed publisher
	Yuan S, Shiau M, Ou Y, Huang Y, Chen C, Cheng C, et al. Miconazole induces apoptosis via the death receptor 5-dependent and mitochondrial-mediated pathways in human bladder cancer cells. Oncol Rep. 2017;37:3606-3616 pubmed publisher
	Hsu S, Lo C, Pan T, Lee K, Yu M. Serine 235 Is the Primary NS5A Hyperphosphorylation Site Responsible for Hepatitis C Virus Replication. J Virol. 2017;91: pubmed publisher
	Liu Y, Weng Y, Lin H, Tang S, Chen C, Liang C, et al. Aqueous extract of Polygonum bistorta modulates proteostasis by ROS-induced ER stress in human hepatoma cells. Sci Rep. 2017;7:41437 pubmed publisher
	Totty M, Morrell B, Spicer L. Fibroblast growth factor 9 (FGF9) regulation of cyclin D1 and cyclin-dependent kinase-4 in ovarian granulosa and theca cells of cattle. Mol Cell Endocrinol. 2017;440:25-33 pubmed publisher

product information

Catalog Number :

GTX102993

Product Name :

CDK4 antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary Antibody

list of Pubmed id :

21477582,24588135,25429617,27816766,26379747,28134285,25606576,28446668,28498480,29103955

Background :

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq]