Insulin Receptor antibody | GeneTex GTX101136 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

Insulin Receptor antibody

catalog :

GTX101136

quantity :

100.00μl

price :

299 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry - paraffin section

citations: 1

Reference
Chen Y, Lin W, Liao W, Lin Y, Chang J, Tsai F. PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes. Oncotarget. 2015;6:12997-3005 pubmed

product information

Catalog No :

GTX101136

Product Name :

Insulin Receptor antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

List Price :

299 USD

list of Pubmed id :

26079428

Isotype :

IgG

Product Description :

Rabbit Polyclonal antibody to Insulin Receptor (insulin receptor)

CrossReactivity :

Hu, Ms

Background :

After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Immunogen :

Recombinant protein encompassing a sequence within the C-terminus region of human Insulin Receptor. The exact sequence is proprietary.

Buffer :

1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

Uses :

IHC-P, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Image Legend_4 :

Insulin Receptor beta subunit antibody detects Insulin Receptor beta subunit protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with Insulin Receptor beta subunit antibody (GTX101136) diluted by 1:1000.