This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
Caspase 8 antibody [N1C1]
catalog :
GTX100905
quantity :
100.00μl
price :
299 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
product information
Catalog No :
GTX100905
Product Name :
Caspase 8 antibody [N1C1]
Host Species :
Rabbit
Clonality :
Polyclonal
Product Type :
Primary antibody
Size :
100.00μl
List Price :
299 USD
Isotype :
IgG
Product Description :
Rabbit Polyclonal antibody to Caspase 8 (caspase 8, apoptosis-related cysteine peptidase)
CrossReactivity :
Hu
Background :
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined. [provided by RefSeq]
Immunogen :
Recombinant protein encompassing a sequence within the center region of human Caspase 8. The exact sequence is proprietary.
Buffer :
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Uses :
ICC/IF, IHC-P, WB
Concentration :
1mg/ml
General References :
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
company information
GeneTex
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