NQO1 antibody [C2C3], C-term | GeneTex GTX100235 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

NQO1 antibody [C2C3], C-term

catalog :

GTX100235

quantity :

100.00μl

price :

299 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

citations: 2

Reference
Yeh C, Ma K, Liu P, Kuo J, Chueh S. Baicalein Decreases Hydrogen Peroxide-Induced Damage to NG108-15 Cells via Upregulation of Nrf2. J Cell Physiol. 2015;230:1840-51 pubmed publisher
Chen P, Chang J, Li L, Tsai H, Shen M, Lin P. Aryl hydrocarbon receptor is a target of 17-Allylamino-17-demethoxygeldanamycin and enhances its anticancer activity in lung adenocarcinoma cells. Mol Pharmacol. 2013;83:605-12 pubmed publisher

product information

Catalog No :

GTX100235

Product Name :

NQO1 antibody [C2C3], C-term

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μl

List Price :

299 USD

list of Pubmed id :

23229511,25557231

Product Description :

Rabbit Polyclonal antibody to NQO1 (NAD(P)H dehydrogenase, quinone 1)

CrossReactivity :

Hu, Ms, Rat

Background :

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Immunogen :

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NQO1. The exact sequence is proprietary.

Buffer :

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Uses :

ICC/IF, IHC-P, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Image Legend_4 :

Immunohistochemical analysis of paraffin-embedded CL1-0 xenograft, using NQO1(GTX100235) antibody at 1:500 dilution.

Image Legend_5 :

Sample (30 ug of whole cell lysate) A: Molt-4 (GTX27912) B: Raji 12% SDS PAGE GTX100235 diluted at 1:1000