LRRK2 (human) polyclonal antibody (AT106) | Enzo Life Sciences ALX-210-928-C100 product information

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product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

LRRK2 (human) polyclonal antibody (AT106)

catalog :

ALX-210-928-C100

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation

product information

Product ID :

ALX-210-928

Catalog Number :

ALX-210-928-C100

Product Name :

LRRK2 (human) polyclonal antibody (AT106)

Host species :

Rabbit

Clonality :

Polyclonal

Product Type :

Antibody

Size :

100 µg

list of Pubmed id :

17137507

SPECIES REACTIVITY :

Human

Background :

LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features.

ALTnames :

Leucine-rich repeat kinase 2, RIP7, PARK8, Dardarin

Immunogen :

Recombinant human LRRK2 (leucine-rich repeat kinase 2) (aa 1838-2133).

Specificity :

The strongest recognized epitope is PDQPRLTIPISQ (aa 1843-1854) as defined by epitope mapping.

Buffer :

Liquid. In PBS containing 0.02% sodium azide.

Application Summary :

IHC (PS), IP, WB

Storage :

-20°C