Anti-G6PD Antibody, clone EPR6292, rabbit monoclonal | EMD Millipore MABS391 product information

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Anti-G6PD Antibody, clone EPR6292, rabbit monoclonal

catalog :

MABS391

quantity :

100 µL

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

EPR6292

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

EMD Millipore product webpage

product information

Catalog Number :

MABS391

Subcategory :

Cell Signaling

Product Name :

Anti-G6PD Antibody, clone EPR6292, rabbit monoclonal

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P11413

Host Name :

Rabbit

Antigen :

G6PD

Clone :

EPR6292

Conjugate :

Unpurified

Product Description :

Anti-G6PD Antibody, clone EPR6292, rabbit monoclonal

Cross Reactivity :

Human

Background :

Glucose-6-phosphate 1 dehydrogenase (G6PD) is a critical first step enzyme in glucose degradation metabolism and G6PD is a primary source for the production of NADPH (a primary reducer and cofactor in metabolism). The cytosolic enzyme also plays a critical role in protecting red blood cells from oxidative damage and premature destruction because the production of NADPH helps to maintain levels of reduced glutathione. Defects in G6PD causes hemolytic anemia as well as a wide range of other G6PD disorders such as neonatal jaundice, and drug and infection mediated hemolytic crisis. Because G6PD also affects cell growth and proliferation via its influence on NADPH reductive biosynthetic pathways, inhibitors of G6PD are being examined as possible cancer preventatives. EMD-Millipore’s Anti-G6PD rabbit monoclonal antibody has been tested in western blot on various human cancer cell line lysates and in paraffin embedded immunohistochemistry on human testis tissue sections.

ALT Names :

Glucose-6-phosphate 1-dehydrogenase

Immunogen :

Synthetic peptide corresponding to human G6PD.

Package Size :

100 µL

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

more info or order :

EMD Millipore product webpage