VDAC1 Antibody, clone N152B/23 | EMD Millipore MABN504 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

VDAC1 Antibody, clone N152B/23

catalog :

MABN504

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

N152B/23

The same clone is also sold as:

BioLegend: 820703, 820701, 820704, 820702
Abcam: ab186321
OriGene: 75-204, 73-204
Neuromab: 73-204, 75-204

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

citations: 8

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 1b	Yang Y, Luo M, Zhang K, Zhang J, Gao T, Connell D, et al. Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma. Nat Commun. 2020;11:433 pubmed publisher
western blot; mouse; loading ...; fig 2f	McArthur K, Whitehead L, Heddleston J, Li L, Padman B, Oorschot V, et al. BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis. Science. 2018;359: pubmed publisher
western blot; mouse; 1:5000; fig 3d	Mourier A, Motori E, Brandt T, Lagouge M, Atanassov I, Galinier A, et al. Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels. J Cell Biol. 2015;208:429-42 pubmed publisher
western blot; rat	Bobba A, Amadoro G, La Piana G, Petragallo V, Calissano P, Atlante A. Glucose-6-phosphate tips the balance in modulating apoptosis in cerebellar granule cells. FEBS Lett. 2015;589:651-8 pubmed publisher
	Chin H, Li M, Tan I, Ninnis R, Reljic B, Scicluna K, et al. VDAC2 enables BAX to mediate apoptosis and limit tumor development. Nat Commun. 2018;9:4976 pubmed publisher
	Yao G, Zhu Q, Xia J, Chen F, Huang M, Liu J, et al. Ischemic postconditioning confers cerebroprotection by stabilizing VDACs after brain ischemia. Cell Death Dis. 2018;9:1033 pubmed publisher
	Bannwarth S, Ait El Mkadem S, Chaussenot A, Genin E, Lacas Gervais S, Fragaki K, et al. A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement. Brain. 2014;137:2329-45 pubmed publisher
	Ismailoglu I, Chen Q, Popowski M, Yang L, Gross S, Brivanlou A. Huntingtin protein is essential for mitochondrial metabolism, bioenergetics and structure in murine embryonic stem cells. Dev Biol. 2014;391:230-40 pubmed publisher

product information

Catalog Number :

MABN504

Subcategory :

Neuroscience

Product Name :

Anti-VDAC1 Antibody, clone N152B/23

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P21796

Host Name :

Mouse

Antigen :

VDAC1

Clone :

N152B/23

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-VDAC1 Antibody, clone N152B/23

Cross Reactivity :

Human;Mouse;Rat

Background :

Voltage-dependent anion-selective channel protein 1 (VDAC1, VDAC), also known as outer mitochondrial membrane protein porin 1, is the outer mitochondrial membrane receptor for hexokinase and BCL2L1. VDAC1 forms a channel through the mitochondrial membrane and is involved in small molecule diffusion, cell volume regulation and apoptosis. VDAC1 may participate in the formation of the permeability transition pore complex (PTPC), which is responsible for the release of mitochondrial products that triggers apoptosis.

ALT Names :

Voltage-dependent anion-selective channel protein 1;VDAC-1;hVDAC1;Outer mitochondrial membrane protein porin 1;Plasmalemmal porin;Porin 31HL;Porin 31HM

Immunogen :

Recombinant protein corresponding to human VDAC1.

Specificity :

This antibody does not cross-react with VDAC2 or VDAC3 (Prof. J. Trimmer, University of California, Davis).

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt