Sox1 Antibody, clone 2B3.3 | EMD Millipore MABN155 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Sox1 Antibody, clone 2B3.3

catalog :

MABN155

quantity :

200 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2B3.3

reactivity :

mouse

application :

western blot

product information

Catalog Number :

MABN155

Subcategory :

Neuroscience

Product Name :

Anti-Sox1 Antibody, clone 2B3.3

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O00570

Host Name :

Mouse

Antigen :

Sox1

Clone :

2B3.3

Conjugate :

Purified

Isotype :

IgMκ

Product Description :

Anti-Sox1 Antibody, clone 2B3.3

Cross Reactivity :

Mouse

Background :

SRY (Sex determining region Y)-box 1(Sox1), is a transcription factor that is expressed in the developing brain. SOX1 is related to the HMG box of family transcription factors, which are a highly motile group, with a highly conserved DNA binding domain. Sox1 utilizes multiple pathways to play a direct role on cell fate. Sox1 is also directly involved with sex determination of the Y chromosome. Binding of the Sox1, C-terminus, to the Hes 1 promoter results in Hes1 suppression and attenuation of Notch signaling. When the C-terminus of Sox1 binds to β-catenin, TCF/LEF is suppressed, resulting in the attenuation of Wnt signaling. Sox1 may function as a switch in neuronal development.

ALT Names :

Transcription factor SOX-1

Immunogen :

KLH-conjugated linear peptide corresponding to human Sox1.

Package Size :

200 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt