Mouse TNF-alpha ELISA Kit, EZMTNFA | EMD Millipore EZMTNFA product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

ELISA/assay

product name :

Mouse TNF-alpha ELISA Kit, EZMTNFA

catalog :

EZMTNFA

quantity :

96-well strip plate

citations: 1

Reference
Castellani L, Root-McCaig J, Frendo-Cumbo S, Beaudoin M, Wright D. Exercise training protects against an acute inflammatory insult in mouse epididymal adipose tissue. J Appl Physiol (1985). 2014;116:1272-80 pubmed publisher

product information

Category :

Inflammation & Immunology

Catalog Number :

EZMTNFA

Product Name :

Mouse TNF-alpha ELISA Kit, EZMTNFA

Product Type :

Kits & Assays

Product Description :

Mouse TNF-alpha ELISA Kit, EZMTNFA

Background :

Mouse TNF-alpha (Tumor Necrosis Factor alpha) is a potent multifunctional cytokine which can exert regulatory, inflammatory and cytotoxic effects on a wide range of normal lymphoid and non-lymphoid cells and tumor cells. TNF-alpha is secreted by macrophages, monocytes, neutrophils, T-cells (primarily CD4+ T cells), NK- cells, and many transformed cell lines. It exists as a soluble 17.5 kD protein and a 26 kD membrane-associated protein. The soluble form protein derives from the membrane form by proteolytic processing. The membrane form protein, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the membrane form occurs by binding to soluble TNFRSF1A/TNFR1. TNF-alpha binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorrhagic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils. It has been shown that TNF-alpha plays a critical role in many physiological and pathological conditions, including neurodegenerative diseases and cancer.

Package Size :

96-well strip plate

Uses :

ELISA