PICALM Antibody | EMD Millipore ABN465 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PICALM Antibody

catalog :

ABN465

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot

product information

Catalog Number :

ABN465

Subcategory :

Neuroscience

Product Name :

Anti-PICALM Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q13492

Host Name :

Rabbit

Antigen :

PICALM

Conjugate :

Affinity Purified

Product Description :

Anti-PICALM Antibody

Cross Reactivity :

Mouse

Background :

Phosphatidylinositol-binding clathrin assembly protein (PICALM), also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area as a component of the coated pit internalization machinery. PICALM fusion proteins have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia, and chromosomal aberrations are found in diffuse histiocytic lymphomas. PICALM is also expressed in neuronal synapses where it facilitates the endocytosis of VAMP2. PICALM variants are associated with Alzheimer's disease and are thought to be involved in the endocytosis and recycling of the amyloid protein precursor (APP).

ALT Names :

Phosphatidylinositol-binding clathrin assembly protein;LAP;CALM;CLTH;Clathrin assembly lymphoid myeloid leukemia protein

Immunogen :

KLH-conjugated linear peptide corresponding to human PICALM.

Specificity :

This antibody can recognize all isoforms of PICALM.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt