Tyrosine Kinase Receptor C Antibody | EMD Millipore AB9834 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Tyrosine Kinase Receptor C Antibody

catalog :

AB9834

quantity :

50 µL

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry

citations: 2

Reference
Xie H, Cherrington B, Meadows J, Witham E, Mellon P. Msx1 homeodomain protein represses the ?GSU and GnRH receptor genes during gonadotrope development. Mol Endocrinol. 2013;27:422-36 pubmed publisher
Garcia N, Santafe M, Tomas M, Lanuza M, Besalduch N, Tomas J. Involvement of neurotrophin-3 (NT-3) in the functional elimination of synaptic contacts during neuromuscular development. Neurosci Lett. 2010;473:141-5 pubmed publisher

product information

Catalog Number :

AB9834

Subcategory :

Neuroscience

Product Name :

Anti-Tyrosine Kinase Receptor C Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q16288

Host Name :

Rabbit

Antigen :

Tyrosine Kinase Receptor C

Conjugate :

Serum

Product Description :

Anti-Tyrosine Kinase Receptor C Antibody

Cross Reactivity :

Human;Mouse;Rat

Background :

The mammalian Trk family of receptor tyrosine kinases consists of three principle transmembrane proteins. The receptors can be activated by one or more of four neurotrophins - NGF, BDNF, NT3 and NT4. Each of the four members of the TrkC family, expressed by alternative splicing, serves as a receptor for NT-3, with some evidence for endogenous activation also by NGF. These neurotrophins regulate biological responses such as cell survival, proliferation and differentiation in normal and neoplastic neuronal cells primarily, but several other cell types have been shown to express the TrkC receptor. The receptor has also been demonstrated on many tumors of neuronal origin.

ALT Names :

trkC

Immunogen :

Extracellular domain of the recombinant human receptor expressed in mammalian cells.

Specificity :

trkC [Neurotrophin-3 growth factor receptor; tyrosine kinase receptor C]. All four forms of the TrkC receptor are expected to be detected by this antibody. The immunogen sequence was chosen to avoid cross reactivity with trkA or trkB.

Package Size :

50 µL

Uses :

Immunohistochemistry

Storage :

Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.