SOX1 Antibody | EMD Millipore 07-1673 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SOX1 Antibody

catalog :

07-1673

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

immunohistochemistry, immunohistochemistry - paraffin section

product information

Catalog Number :

07-1673

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-SOX1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

O00570

Host Name :

Rabbit

Antigen :

SOX1

Conjugate :

Affinity Purified

Product Description :

Anti-SOX1 Antibody

Cross Reactivity :

Mouse;Human

Background :

Sox-1 protein (SOX1), also known as SRY (Sex determining region Y)-box 1, is expressed in the developing brain. SOX1 is related to the HMG box of family transcription factors, which are a highly motile group, with a highly conserved DNA binding domain. Sox1 utilizes multiple pathways to play a direct role on cell fate. SOX1 is also directly involved with sex determination of the Y chromosome. Binding of the SOX1, C-terminus, to the Hes 1 promoter results in Hes1 suppression and attenuation of Notch signaling. When the C-terminus of SOX1 binds to β-catenin, TCF/LEF is suppressed, resulting in the attenuation of Wnt signaling.

ALT Names :

SRY (sex determining region Y)-box 1;SRY-related HMG-box gene 1

Immunogen :

Synthetic peptide corresponding to SOX1.

Specificity :

This antibody recognizes SOX1.

Package Size :

100 μg

Uses :

Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8ºC from date of receipt. To reconstitute the antibody, centrifuge the antibody at a moderate speed (5,000 rpm) for 5 minutes. Carefully remove the ammonium sulfate/PBS buffer solution and discard; 10 μL of residual ammonium sulfate solution will not affect the re-suspension of the antibody. Do not let the protein pellet dry, as severe loss of antibody reactivity can occur. Re-suspend the antibody pellet in 100L either standard PBS or TBS (pH 7.3-7.5). DO NOT VORTEX. Mix by gentle stirring with a wide pipet tip or gentle finger-tapping. Let the precipitated antibody rehydrate for 1 hour at 25°C prior to use. Small particles of precipitated antibody that fail to re-suspend are normal. Vials are overfilled to compensate for any losses.