| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:1000; loading ...; fig 4g
| Xiong Y, Li L, Zhang L, Cui Y, Wu C, Li H, et al. The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression. Cell Death Differ. 2019;: pubmed publisher
|
- immunocytochemistry; human; loading ...; fig 1c
| Sharma P, Lioutas A, Fernandez Fuentes N, Quilez J, Carbonell Caballero J, Wright R, et al. Arginine Citrullination at the C-Terminal Domain Controls RNA Polymerase II Transcription. Mol Cell. 2019;73:84-96.e7 pubmed publisher
|
- immunoprecipitation; human; loading ...; fig 6d
| Fujimoto M, Takii R, Katiyar A, Srivastava P, Nakai A. Poly(ADP-Ribose) Polymerase 1 Promotes the Human Heat Shock Response by Facilitating Heat Shock Transcription Factor 1 Binding to DNA. Mol Cell Biol. 2018;38: pubmed publisher
|
- immunoprecipitation; human; loading ...; fig 5f
- western blot; human; 1:1000; loading ...; fig 5f
| Slobodin B, Han R, Calderone V, Vrielink J, Loayza Puch F, Elkon R, et al. Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation. Cell. 2017;169:326-337.e12 pubmed publisher
|
- chromatin immunoprecipitation; human; loading ...; fig 4c
| Audet Walsh E, Yee T, Tam I, Giguere V. Inverse Regulation of DHT Synthesis Enzymes 5?-Reductase Types 1 and 2 by the Androgen Receptor in Prostate Cancer. Endocrinology. 2017;158:1015-1021 pubmed publisher
|
- chromatin immunoprecipitation; mouse; loading ...; fig 5f
| Ma J, Sanchez B, Hall D, Tremblay A, Di Marco S, Gallouzi I. STAT3 promotes IFNγ/TNFα-induced muscle wasting in an NF-κB-dependent and IL-6-independent manner. EMBO Mol Med. 2017;9:622-637 pubmed publisher
|
- chromatin immunoprecipitation; rat; loading ...; tbl 1
| Kumar A, Dumasia K, Deshpande S, Balasinor N. Direct regulation of genes involved in sperm release by estrogen and androgen through their receptors and coregulators. J Steroid Biochem Mol Biol. 2017;171:66-74 pubmed publisher
|
- chromatin immunoprecipitation; mouse; loading ...; fig 5a
- chromatin immunoprecipitation; human; loading ...; fig 5b
| Vispute S, Bu P, Le Y, Cheng X. Activation of GR but not PXR by dexamethasone attenuated acetaminophen hepatotoxicities via Fgf21 induction. Toxicology. 2017;378:95-106 pubmed publisher
|
- chromatin immunoprecipitation; human; loading ...; fig 5b
| Hentati Kallel M, Le Jan S, Bernard P, Antonicelli F, Trussardi Regnier A. Histone deacetylases meet microRNA-associated MMP-9 expression regulation in glucocorticoid-sensitive and -resistant cell lines. Int J Oncol. 2017;50:717-726 pubmed publisher
|
- chromatin immunoprecipitation; human; loading ...; fig 5b
| Vuono E, Mukherjee A, Vierra D, Adroved M, Hodson C, Deans A, et al. The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair. Sci Rep. 2016;6:36439 pubmed publisher
|
- chromatin immunoprecipitation; human; loading ...; fig 2e
| Su C, Lin I, Tzeng T, Hsieh W, Hsu M. Regulation of IL-20 Expression by Estradiol through KMT2B-Mediated Epigenetic Modification. PLoS ONE. 2016;11:e0166090 pubmed publisher
|
- chromatin immunoprecipitation; mouse; loading ...
| Tahmasebi S, Jafarnejad S, Tam I, Gonatopoulos Pournatzis T, Matta Camacho E, Tsukumo Y, et al. Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2. Proc Natl Acad Sci U S A. 2016;113:12360-12367 pubmed
|
- chromatin immunoprecipitation; human; loading ...; fig 3j
| Harrod A, Fulton J, Nguyen V, Periyasamy M, Ramos Garcia L, Lai C, et al. Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer. Oncogene. 2017;36:2286-2296 pubmed publisher
|
- chromatin immunoprecipitation; human; fig 4
| Wu H, Li S, Hu J, Yu X, Xu H, Chen Z, et al. Demystifying the mechanistic and functional aspects of p21 gene activation with double-stranded RNAs in human cancer cells. J Exp Clin Cancer Res. 2016;35:145 pubmed publisher
|
| Gilan O, Lam E, Becher I, Lugo D, Cannizzaro E, Joberty G, et al. Functional interdependence of BRD4 and DOT1L in MLL leukemia. Nat Struct Mol Biol. 2016;23:673-81 pubmed publisher
|
- western blot; human; 1:4000; fig 1
| Kalantari R, Hicks J, Li L, Gagnon K, Sridhara V, Lemoff A, et al. Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells. RNA. 2016;22:1085-98 pubmed publisher
|
- chromatin immunoprecipitation; human; loading ...; fig 2d
| Park S, Yi H, Suh N, Park Y, Koh J, Jeong S, et al. Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-?B. Oncotarget. 2016;7:39796-39808 pubmed publisher
|
- chromatin immunoprecipitation; human; loading ...; fig 7e
| Yamashita D, Moriuchi T, Osumi T, Hirose F. Transcription Factor hDREF Is a Novel SUMO E3 Ligase of Mi2α. J Biol Chem. 2016;291:11619-34 pubmed publisher
|
- immunocytochemistry; human; 1:200; fig 6g
| Shao Z, Zhang R, Khodadadi Jamayran A, Chen B, Crowley M, Festok M, et al. The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis. Nat Commun. 2016;7:10869 pubmed publisher
|
- western blot; human; 1:1000; fig 7
| Scheckel C, Drapeau E, Frias M, Park C, Fak J, Zucker Scharff I, et al. Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain. elife. 2016;5: pubmed publisher
|
- chromatin immunoprecipitation; human; 1:100; fig 5b
| Wang X, Jung Y, Jun S, Lee S, Wang W, Schneider A, et al. PAF-Wnt signaling-induced cell plasticity is required for maintenance of breast cancer cell stemness. Nat Commun. 2016;7:10633 pubmed publisher
|
- immunocytochemistry; mouse; 1:200; fig 5
| Ancelin K, Syx L, Borensztein M, Ranisavljevic N, Vassilev I, Briseño Roa L, et al. Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation. elife. 2016;5: pubmed publisher
|
- chromatin immunoprecipitation; mouse; loading ...; fig 4c
| Hessmann E, Zhang J, Chen N, Hasselluhn M, Liou G, Storz P, et al. NFATc4 Regulates Sox9 Gene Expression in Acinar Cell Plasticity and Pancreatic Cancer Initiation. Stem Cells Int. 2016;2016:5272498 pubmed publisher
|
- chromatin immunoprecipitation; human
| Madsen A, Bozickovic O, Bjune J, Mellgren G, Sagen J. Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2). Sci Rep. 2015;5:16430 pubmed publisher
|
- chromatin immunoprecipitation; human; 10 ul/mg; fig 8
| Su S, Zhao Q, He C, Huang D, Liu J, Chen F, et al. miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program. Nat Commun. 2015;6:8523 pubmed publisher
|
- immunohistochemistry; Saccharum sp.; 1:300
| Moraes I, Yuan Z, Liu S, Souza G, Garcia B, Casas Mollano J. Analysis of Histones H3 and H4 Reveals Novel and Conserved Post-Translational Modifications in Sugarcane. PLoS ONE. 2015;10:e0134586 pubmed publisher
|
- chromatin immunoprecipitation; mouse; fig 6
| Tan K, Fujimoto M, Takii R, Takaki E, Hayashida N, Nakai A. Mitochondrial SSBP1 protects cells from proteotoxic stresses by potentiating stress-induced HSF1 transcriptional activity. Nat Commun. 2015;6:6580 pubmed publisher
|
- chromatin immunoprecipitation; mouse; fig 6
| Gillespie M, Gold E, Ramsey S, Podolsky I, Aderem A, Ranish J. An LXR-NCOA5 gene regulatory complex directs inflammatory crosstalk-dependent repression of macrophage cholesterol efflux. EMBO J. 2015;34:1244-58 pubmed publisher
|
- western blot; human; fig 4
| García Carmona Y, Cols M, Ting A, Radigan L, Yuk F, Zhang L, et al. Differential induction of plasma cells by isoforms of human TACI. Blood. 2015;125:1749-58 pubmed publisher
|
- western blot; Saccharomycetales
| Allepuz Fuster P, MartÃnez Fernández V, Garrido Godino A, Alonso Aguado S, Hanes S, Navarro F, et al. Rpb4/7 facilitates RNA polymerase II CTD dephosphorylation. Nucleic Acids Res. 2014;42:13674-88 pubmed
|
- chromatin immunoprecipitation; human; fig 1
| Maruyama A, Mimura J, Itoh K. Non-coding RNA derived from the region adjacent to the human HO-1 E2 enhancer selectively regulates HO-1 gene induction by modulating Pol II binding. Nucleic Acids Res. 2014;42:13599-614 pubmed publisher
|
- immunoprecipitation; human
| Zhou Z, Wang R, Yang X, Lu X, Zhang Q, Wang Y, et al. The cAMP-responsive element binding protein (CREB) transcription factor regulates furin expression during human trophoblast syncytialization. Placenta. 2014;35:907-18 pubmed publisher
|
- chromatin immunoprecipitation; human
| Wright R, Slemmons K, Vaughan A. Estradiol induces gene proximity and MLL-MLLT3 fusion in an activation-induced cytidine deaminase-mediated pathway. Leuk Lymphoma. 2015;56:1460-5 pubmed publisher
|
- immunoprecipitation; Saccharomycetales
| Mirón García M, Garrido Godino A, Martínez Fernández V, Fernández Pévida A, Cuevas Bermúdez A, Martín Expósito M, et al. The yeast prefoldin-like URI-orthologue Bud27 associates with the RSC nucleosome remodeler and modulates transcription. Nucleic Acids Res. 2014;42:9666-76 pubmed publisher
|
- chromatin immunoprecipitation; rat
| Baby N, Li Y, Ling E, Lu J, Dheen S. Runx1t1 (Runt-related transcription factor 1; translocated to, 1) epigenetically regulates the proliferation and nitric oxide production of microglia. PLoS ONE. 2014;9:e89326 pubmed publisher
|
- immunoprecipitation; mouse
| Meng L, Person R, Huang W, Zhu P, Costa Mattioli M, Beaudet A. Truncation of Ube3a-ATS unsilences paternal Ube3a and ameliorates behavioral defects in the Angelman syndrome mouse model. PLoS Genet. 2013;9:e1004039 pubmed publisher
|
- chromatin immunoprecipitation; human
| Maruyama A, Mimura J, Harada N, Itoh K. Nrf2 activation is associated with Z-DNA formation in the human HO-1 promoter. Nucleic Acids Res. 2013;41:5223-34 pubmed publisher
|
- chromatin immunoprecipitation; mouse
| Panigrahi S, Vasileva A, Wolgemuth D. Sp1 transcription factor and GATA1 cis-acting elements modulate testis-specific expression of mouse cyclin A1. PLoS ONE. 2012;7:e47862 pubmed publisher
|
- immunocytochemistry; mouse; loading ...; fig 3m
| Modzelewski A, Holmes R, Hilz S, Grimson A, Cohen P. AGO4 regulates entry into meiosis and influences silencing of sex chromosomes in the male mouse germline. Dev Cell. 2012;23:251-64 pubmed publisher
|
- immunocytochemistry; human
| Sims R, Rojas L, Beck D, Bonasio R, Schüller R, Drury W, et al. The C-terminal domain of RNA polymerase II is modified by site-specific methylation. Science. 2011;332:99-103 pubmed publisher
|
- chromatin immunoprecipitation; human
| Karius T, Schnekenburger M, Ghelfi J, Walter J, Dicato M, Diederich M. Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines. Biochem Pharmacol. 2011;81:1329-42 pubmed publisher
|
- chromatin immunoprecipitation; human
| Milagre I, Nunes M, Moutinho M, Rivera I, Fuso A, Scarpa S, et al. Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination. J Alzheimers Dis. 2010;22:1209-21 pubmed publisher
|
- immunoprecipitation; human
| Guo D, Prins R, Dang J, Kuga D, Iwanami A, Soto H, et al. EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy. Sci Signal. 2009;2:ra82 pubmed publisher
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- immunocytochemistry; human; 1:500
| Nayak A, Glöckner Pagel J, Vaeth M, Schumann J, Buttmann M, Bopp T, et al. Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylase. J Biol Chem. 2009;284:10935-46 pubmed publisher
|
- chromatin immunoprecipitation; mouse
| Schnekenburger M, Talaska G, Puga A. Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation. Mol Cell Biol. 2007;27:7089-101 pubmed
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| Chappidi N, Nascakova Z, Boleslavska B, Zellweger R, Isik E, Andrs M, et al. Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops. Mol Cell. 2019;: pubmed publisher
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| Baquero Perez B, Antanaviciute A, Yonchev I, Carr I, Wilson S, Whitehouse A. The Tudor SND1 protein is an m6A RNA reader essential for replication of Kaposi's sarcoma-associated herpesvirus. elife. 2019;8: pubmed publisher
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| Rossi M, Bucci G, Rizzotto D, Bordo D, Marzi M, Puppo M, et al. LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-β. Nat Commun. 2019;10:1969 pubmed publisher
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| Kumar M, Kasti K, Balakrishnan L, Milavetz B. Directed Nucleosome Sliding during the Formation of the Simian Virus 40 Particle Exposes DNA Sequences Required for Early Transcription. J Virol. 2019;93: pubmed publisher
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| Bornelöv S, Reynolds N, Xenophontos M, Gharbi S, Johnstone E, Floyd R, et al. The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression. Mol Cell. 2018;71:56-72.e4 pubmed publisher
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| Cannizzaro E, Bannister A, Han N, Alendar A, Kouzarides T. DDX3X RNA helicase affects breast cancer cell cycle progression by regulating expression of KLF4. FEBS Lett. 2018;592:2308-2322 pubmed publisher
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| Kim M, Xia B, Suh H, Lee S, Jun S, Lien E, et al. PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis. Dev Cell. 2018;44:582-596.e4 pubmed publisher
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| Tan X, Banerjee P, Liu X, Yu J, Gibbons D, Wu P, et al. The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network. J Clin Invest. 2018;128:1267-1282 pubmed publisher
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| Yan T, Ooi W, Qamra A, Cheung A, Ma D, Sundaram G, et al. HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis. Nat Commun. 2018;9:100 pubmed publisher
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| Chen J, Teo B, Cai Y, Wee S, Lu J. The linker histone H1.2 is a novel component of the nucleolar organizer regions. J Biol Chem. 2018;293:2358-2369 pubmed publisher
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| Bugge M, Bergstrom B, Eide O, Solli H, Kjønstad I, Stenvik J, et al. Surface Toll-like receptor 3 expression in metastatic intestinal epithelial cells induces inflammatory cytokine production and promotes invasiveness. J Biol Chem. 2017;292:15408-15425 pubmed publisher
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| Lu W, Katzenellenbogen B. Estrogen Receptor-? Modulation of the ER?-p53 Loop Regulating Gene Expression, Proliferation, and Apoptosis in Breast Cancer. Horm Cancer. 2017;8:230-242 pubmed publisher
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| Ono R, Masuya M, Ishii S, Katayama N, Nosaka T. Eya2, a Target Activated by Plzf, Is Critical for PLZF-RARA-Induced Leukemogenesis. Mol Cell Biol. 2017;37: pubmed publisher
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| Ganti K, Mukherji A, Surjit M, Li M, Chambon P. Similarities and differences in the transcriptional control of expression of the mouse TSLP gene in skin epidermis and intestinal epithelium. Proc Natl Acad Sci U S A. 2017;114:E951-E960 pubmed publisher
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| Yang C, Li Z, Bhatt T, Dickler M, Giri D, Scaltriti M, et al. Acquired CDK6 amplification promotes breast cancer resistance to CDK4/6 inhibitors and loss of ER signaling and dependence. Oncogene. 2017;36:2255-2264 pubmed publisher
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| MartÃnez Alonso M, Hengrung N, Fodor E. RNA-Free and Ribonucleoprotein-Associated Influenza Virus Polymerases Directly Bind the Serine-5-Phosphorylated Carboxyl-Terminal Domain of Host RNA Polymerase II. J Virol. 2016;90:6014-6021 pubmed publisher
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| Takemata N, Oda A, Yamada T, Galipon J, Miyoshi T, Suzuki Y, et al. Local potentiation of stress-responsive genes by upstream noncoding transcription. Nucleic Acids Res. 2016;44:5174-89 pubmed publisher
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| Banerjee A, Kim Y, Kim T. A novel virus-inducible enhancer of the interferon-β gene with tightly linked promoter and enhancer activities. Nucleic Acids Res. 2014;42:12537-54 pubmed publisher
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| Hsu C, Liu J, Wu P, Guan H, Chen Y, Lin A, et al. Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol. 2014;8:1575-87 pubmed publisher
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| He Y, Tsuei J, Wan Y. Biological functional annotation of retinoic acid alpha and beta in mouse liver based on genome-wide binding. Am J Physiol Gastrointest Liver Physiol. 2014;307:G205-18 pubmed publisher
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| Khurana J, Wang X, Chen X, Perlman D, Landweber L. Transcription-independent functions of an RNA polymerase II subunit, Rpb2, during genome rearrangement in the ciliate, Oxytricha trifallax. Genetics. 2014;197:839-49 pubmed publisher
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| Sonzogni S, Ogara M, Belluscio L, Castillo D, Scassa M, Cánepa E. p19INK4d is involved in the cellular senescence mechanism contributing to heterochromatin formation. Biochim Biophys Acta. 2014;1840:2171-83 pubmed publisher
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| Shimoyama S, Kasai S, Kahn Perlès B, Kikuchi H. Dephosphorylation of Sp1 at Ser-59 by protein phosphatase 2A (PP2A) is required for induction of CYP1A1 transcription after treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin or omeprazole. Biochim Biophys Acta. 2014;1839:107-15 pubmed publisher
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| Parikh N, Hilsenbeck S, Creighton C, Dayaram T, Shuck R, Shinbrot E, et al. Effects of TP53 mutational status on gene expression patterns across 10 human cancer types. J Pathol. 2014;232:522-33 pubmed publisher
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| Angulo Rojo C, Manning Cela R, Aguirre A, Ortega A, Lopez Bayghen E. Involvement of the Notch pathway in terminal astrocytic differentiation: role of PKA. ASN Neuro. 2013;5:e00130 pubmed publisher
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| Tanaka Nakanishi A, Yasunaga J, Takai K, Matsuoka M. HTLV-1 bZIP factor suppresses apoptosis by attenuating the function of FoxO3a and altering its localization. Cancer Res. 2014;74:188-200 pubmed publisher
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| Huang V, Zheng J, Qi Z, Wang J, Place R, Yu J, et al. Ago1 Interacts with RNA polymerase II and binds to the promoters of actively transcribed genes in human cancer cells. PLoS Genet. 2013;9:e1003821 pubmed publisher
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| Seidel C, Schnekenburger M, Dicato M, Diederich M. Antiproliferative and proapoptotic activities of 4-hydroxybenzoic acid-based inhibitors of histone deacetylases. Cancer Lett. 2014;343:134-46 pubmed publisher
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| Lim H, Dimova N, Tan M, Sigoillot F, King R, Shi Y. The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20. Mol Cell Biol. 2013;33:4166-80 pubmed publisher
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| Garrido Godino A, García López M, Navarro F. Correct assembly of RNA polymerase II depends on the foot domain and is required for multiple steps of transcription in Saccharomyces cerevisiae. Mol Cell Biol. 2013;33:3611-26 pubmed publisher
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| Son J, Chae C, Hwang J, Park Z, Im S. Enhanced chromatin accessibility and recruitment of JUNB mediate the sustained IL-4 expression in NFAT1 deficient T helper 2 cells. PLoS ONE. 2011;6:e22042 pubmed publisher
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| Zhou D, Pan Y. Gestational low protein diet selectively induces the amino acid response pathway target genes in the liver of offspring rats through transcription factor binding and histone modifications. Biochim Biophys Acta. 2011;1809:549-56 pubmed publisher
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| Chuang Y, Huang W, Park S, Persaud S, Hung C, Ho P, et al. Promyelocytic leukemia protein in retinoic acid-induced chromatin remodeling of Oct4 gene promoter. Stem Cells. 2011;29:660-9 pubmed publisher
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| Lee M, Partridge N. Parathyroid hormone activation of matrix metalloproteinase-13 transcription requires the histone acetyltransferase activity of p300 and PCAF and p300-dependent acetylation of PCAF. J Biol Chem. 2010;285:38014-22 pubmed publisher
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