This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
VHL Antibody
catalog :
2738
quantity :
100 ul
price :
235 USD
clonality :
polyclonal
host :
rabbit
reactivity :
African green monkey, , human, mouse, rat, cow
application :
western blot, immunocytochemistry
citations: 12
Published Application/Species/DilutionReference
  • western blot; human; 1:500; fig 4
Lee S, Frattini V, Bansal M, Castano A, Sherman D, Hutchinson K, et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016;529:172-7 pubmed publisher
  • western blot; mouse; 1:1000
Bangs F, Schrode N, Hadjantonakis A, Anderson K. Lineage specificity of primary cilia in the mouse embryo. Nat Cell Biol. 2015;17:113-22 pubmed publisher
  • immunocytochemistry; African green monkey
  • immunocytochemistry; human
Yu X, Chen S, Hou P, Wang M, Chen Y, Guo D. VHL negatively regulates SARS coronavirus replication by modulating nsp16 ubiquitination and stability. Biochem Biophys Res Commun. 2015;459:270-6 pubmed publisher
  • western blot; human; fig 2a
Liu X, Yao J, Tripathi D, Ding Z, Xu Y, Sun M, et al. Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis. Oncogene. 2015;34:2450-60 pubmed publisher
  • western blot; human
Ding Z, German P, Bai S, Reddy A, Liu X, Sun M, et al. Genetic and pharmacological strategies to refunctionalize the von Hippel Lindau R167Q mutant protein. Cancer Res. 2014;74:3127-36 pubmed publisher
German P, Bai S, Liu X, Sun M, Zhou L, Kalra S, et al. Phosphorylation-dependent cleavage regulates von Hippel Lindau proteostasis and function. Oncogene. 2016;35:4973-80 pubmed publisher
Chen K, Zeng J, Xiao H, Huang C, Hu J, Yao W, et al. Regulation of glucose metabolism by p62/SQSTM1 through HIF1α. J Cell Sci. 2016;129:817-30 pubmed publisher
Chen K, Yu G, Gumireddy K, Li A, Yao W, Gao L, et al. ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer. Oncotarget. 2015;6:6959-76 pubmed
Torrado M, Franco D, Lozano-Velasco E, Hernández-Torres F, Calviño R, Aldama G, et al. A MicroRNA-Transcription Factor Blueprint for Early Atrial Arrhythmogenic Remodeling. Biomed Res Int. 2015;2015:263151 pubmed publisher
Snell C, Turley H, McIntyre A, Li D, Masiero M, Schofield C, et al. Proline-hydroxylated hypoxia-inducible factor 1α (HIF-1α) upregulation in human tumours. PLoS ONE. 2014;9:e88955 pubmed publisher
Guo Y, Schoell M, Freeman R. The von Hippel-Lindau protein sensitizes renal carcinoma cells to apoptotic stimuli through stabilization of BIM(EL). Oncogene. 2009;28:1864-74 pubmed publisher
Li X, Garcia K, Sun Z, Xiao Z. Temporal regulation of rapamycin on memory CTL programming by IL-12. PLoS ONE. 2011;6:e25177 pubmed publisher
product information
SKU :
2738S
Product-Name :
VHL Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, (B)
Applications :
Western blot
Product-Category :
Ubiquitin and Ubiquitin-like proteins
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
24
Host :
Rabbit
Target :
VHL
Primary-Protein :
VHL
Alt-Names :
HRCA1,Protein G7,RCA1,VHL,VHL1,Von Hippel-Lindau disease tumor suppressor,elongin binding protein,pVHL,von Hippel-Lindau tumor suppressor
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.