This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
LEAF™ Purified anti-mouse CD120a (TNF R Type I/p55)
catalog :
113102
quantity :
500 μg
price :
300 USD
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
55R-593
reactivity :
mouse
application :
neutralization, immunoprecipitation, flow cytometry
citations: 3
Reference
Peng J, Li X, Zhang G, Cheng Y, Chen X, Gu W, et al. TNF-TNFR2 Signaling Inhibits Th2 and Th17 Polarization and Alleviates Allergic Airway Inflammation. Int Arch Allergy Immunol. 2019;178:281-290 pubmed publisher
Zhang K, Li Y, Guo Y, Zheng K, Yang Q, Yang L, et al. Elevated progranulin contributes to synaptic and learning deficit due to loss of fragile X mental retardation protein. Brain. 2017;: pubmed publisher
Yan W, Ding A, Kim H, Zheng H, Wei F, Ma X. Progranulin Controls Sepsis via C/EBP?-Regulated Il10 Transcription and Ubiquitin Ligase/Proteasome-Mediated Protein Degradation. J Immunol. 2016;197:3393-3405 pubmed
product information
Antigen :
CD120a
Apps. Abbrev. :
Flow Cytometry, Block, IP
Cat # :
113102
Clone :
55R-593
Item :
LEAF™ Purified anti-mouse CD120a (TNF R Type I/p55)
Isotype :
Armenian Hamster IgG
Other Names :
TNFR type I, TNFRI, TNFR60, p55, TNFRSF1A
Size :
500 μg
Price (USD) :
300 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
LEAF
Immunogen :
E. coli -expressed extracellular domain of the mouse TNFRI protein
Application Notes :
The 55R-593 antibody is useful for immunoprecipitation 1 , in vitro and in vivo receptor blocking 1 , and for use as an agonist of TNF-α. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated anti-Armenian hamster IgG second step (Cat. No. 405501), followed by SAv-PE (Cat. No. 405204)). The Ultra-LEAF™ Purified antibody (Endotoxin 0.01 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 113103 and 113104).
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA