This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3.1-300(HAT-)
catalog :
23254
citations: 11
Reference
Cheng Q, Shang Y, Huang W, Zhang Q, Li X, Zhou Q. p300 mediates the histone acetylation of ORMDL3 to affect airway inflammation and remodeling in asthma. Int Immunopharmacol. 2019;76:105885 pubmed publisher
Mahmud Z, Gomes A, Lee H, Aimjongjun S, Jiramongkol Y, YAO S, et al. EP300 and SIRT1/6 Co-Regulate Lapatinib Sensitivity Via Modulating FOXO3-Acetylation and Activity in Breast Cancer. Cancers (Basel). 2019;11: pubmed publisher
Son S, Park S, Lee H, Siddiqi F, Lee J, Menzies F, et al. Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A. Cell Metab. 2019;29:192-201.e7 pubmed publisher
Sacta M, Tharmalingam B, Coppo M, Rollins D, Deochand D, Benjamin B, et al. Gene-specific mechanisms direct glucocorticoid-receptor-driven repression of inflammatory response genes in macrophages. elife. 2018;7: pubmed publisher
Boudreau H, Ma W, Korzeniowska A, Park J, Bhagwat M, Leto T. Histone modifications affect differential regulation of TGFβ- induced NADPH oxidase 4 (NOX4) by wild-type and mutant p53. Oncotarget. 2017;8:44379-44397 pubmed publisher
Andrews P, Kao K. Wnt/?-catenin-dependent acetylation of Pygo2 by CBP/p300 histone acetyltransferase family members. Biochem J. 2016;473:4193-4203 pubmed
Pasquel D, Doricakova A, Li H, Kortagere S, Krasowski M, Biswas A, et al. Acetylation of lysine 109 modulates pregnane X receptor DNA binding and transcriptional activity. Biochim Biophys Acta. 2016;1859:1155-1169 pubmed publisher
Ogiwara H, Sasaki M, Mitachi T, Oike T, Higuchi S, Tominaga Y, et al. Targeting p300 Addiction in CBP-Deficient Cancers Causes Synthetic Lethality by Apoptotic Cell Death due to Abrogation of MYC Expression. Cancer Discov. 2016;6:430-45 pubmed publisher
Chen W, Jia W, Wang K, Si X, Zhu S, Duan T, et al. Distinct roles for CBP and p300 on the RA-mediated expression of the meiosis commitment gene Stra8 in mouse embryonic stem cells. PLoS ONE. 2013;8:e66076 pubmed publisher
He H, Yu F, Sun C, Luo Y. CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes. PLoS ONE. 2011;6:e22088 pubmed publisher
Chen L, Mu Y, Greene W. Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB. EMBO J. 2002;21:6539-48 pubmed
product information
Catalog Number :
23254
Product Name :
pcDNA3.1-300(HAT-)
article :
doi10.1093/emboj/cdf660
id3110
pubmed_id12456660
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1 (-)
backbone_mutation
backbone_originInvitrogen
backbone_size5428
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3HindIII
cloning_site_5NotI
promoter
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesKAT3B, MKHK2, RSTS2, p300
geneEP300
id2033
genbank_ids
mutationH1415A E1423A Y1424A L1428S Y1430A H1434A
namep300
shRNA_sequence
size7245
species
9606
Homo sapiens
tags
resistance markers :
176
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA