This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-HA2-Keap1
catalog :
21556
citations: 5
Reference
Ganner A, Pfeiffer Z, Wingendorf L, Kreis S, Klein M, Walz G, et al. The acetyltransferase p300 regulates NRF2 stability and localization. Biochem Biophys Res Commun. 2020;524:895-902 pubmed publisher
Riis S, Murray J, O Connor R. IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β-Nrf2-BNIP3 Pathway. Cells. 2020;9: pubmed publisher
Kerins M, Ooi A. A catalogue of somatic NRF2 gain-of-function mutations in cancer. Sci Rep. 2018;8:12846 pubmed publisher
Perez Leal O, Barrero C, Merali S. Pharmacological stimulation of nuclear factor (erythroid-derived 2)-like 2 translation activates antioxidant responses. J Biol Chem. 2017;292:14108-14121 pubmed publisher
Furukawa M, Xiong Y. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase. Mol Cell Biol. 2005;25:162-71 pubmed
product information
Catalog Number :
21556
Product Name :
pcDNA3-HA2-Keap1
article :
doi10.1128/MCB.25.1.162-171.2005
id2686
pubmed_id15601839
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3-HA2
backbone_mutation
backbone_origin
backbone_size5512
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth temp :
37
inserts :
alt_names
KEAP1
INrf2
cloning
clone_methodRestriction Enzyme
cloning_site_3XbaI
cloning_site_5BamHI
promoter
sequencing_primer_3SP6
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesINrf2, KLHL19
geneKEAP1
id9817
genbank_ids
Q14145
mutation
namekelch-like ECH-associated protein 1
shRNA_sequence
size1853
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagHA2
pi :
593
plasmid copy :
High Copy
terms :
MTA
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA