LRRK2-WT | Addgene 17609 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

LRRK2-WT

catalog :

17609

citations: 4

Reference
Yu M, Arshad M, Wang W, Zhao D, Xu L, Zhou L. LRRK2 mediated Rab8a phosphorylation promotes lipid storage. Lipids Health Dis. 2018;17:34 pubmed publisher
Penney J, Tsurudome K, Liao E, Kauwe G, Gray L, Yanagiya A, et al. LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction. Nat Commun. 2016;7:12188 pubmed publisher
Prabhudesai S, Bensabeur F, Abdullah R, Basak I, Baez S, Alves G, et al. LRRK2 knockdown in zebrafish causes developmental defects, neuronal loss, and synuclein aggregation. J Neurosci Res. 2016;94:717-35 pubmed publisher
West A, Moore D, Biskup S, Bugayenko A, Smith W, Ross C, et al. Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. Proc Natl Acad Sci U S A. 2005;102:16842-7 pubmed

product information

Catalog Number :

17609

Product Name :

LRRK2-WT

article :

doi	10.1073/pnas.0507360102
id	4946
pubmed_id	16269541

bacterial resistance :

Ampicillin

cloning :

backbone

pcDNA3.1 myc/his A

backbone_mutation

backbone_origin

Invitrogen

backbone_size

5500

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

growth notes :

Compared to GenBank reference sequence NP_940980.3, the LRRK2 insert in this plasmid contains a M2397T mutation.

growth temp :

Stbl3, 30 degrees

origin :

pi :

alt_names

cloning

clone_method	Restriction Enzyme
cloning_site_3	XhoI
cloning_site_5	BamHI
promoter
sequencing_primer_3	BGH-rev
sequencing_primer_5	CMV-F
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	AURA17, DARDARIN, PARK8, RIPK7, ROCO2
gene	LRRK2
id	120892

genbank_ids

mutation

name

LRRK2

shRNA_sequence

size

7380

species

9606

Homo sapiens