This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Ascent Scientific
product type :
antibody
product name :
Cyclin A antibody
catalog :
ab7956
quantity :
1 ml
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 20
Published Application/Species/DilutionReference
  • immunohistochemistry - paraffin section; mouse
  • immunohistochemistry - paraffin section; rat
  • immunocytochemistry; mouse
  • immunocytochemistry; rat
  • western blot; rat
Li Y, Hu S, Ma G, Yao Y, Yan G, Chen J, et al. Acute myocardial infarction induced functional cardiomyocytes to re-enter the cell cycle. Am J Transl Res. 2013;5:327-35 pubmed
Jiao Y, Ye D, Li Z, Teta-Bissett M, Peng Y, Taub R, et al. Protein tyrosine phosphatase of liver regeneration-1 is required for normal timing of cell cycle progression during liver regeneration. Am J Physiol Gastrointest Liver Physiol. 2015;308:G85-91 pubmed publisher
Wu J, Chen Z, Liu Q, Zeng W, Wu X, Lin B. Silencing of Kv1.5 Gene Inhibits Proliferation and Induces Apoptosis of Osteosarcoma Cells. Int J Mol Sci. 2015;16:26914-26 pubmed publisher
Sebastian S, Sreenivas P, Sambasivan R, Cheedipudi S, Kandalla P, Pavlath G, et al. MLL5, a trithorax homolog, indirectly regulates H3K4 methylation, represses cyclin A2 expression, and promotes myogenic differentiation. Proc Natl Acad Sci U S A. 2009;106:4719-24 pubmed publisher
Chen J, Cohen M, Lerner A, Yang Y, Herrup K. DNA damage and cell cycle events implicate cerebellar dentate nucleus neurons as targets of Alzheimer's disease. Mol Neurodegener. 2010;5:60 pubmed publisher
Yang Y, Varvel N, Lamb B, Herrup K. Ectopic cell cycle events link human Alzheimer's disease and amyloid precursor protein transgenic mouse models. J Neurosci. 2006;26:775-84 pubmed
Sivilia S, Lorenzini L, Giuliani A, Gusciglio M, Fernandez M, Baldassarro V, et al. Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice. BMC Neurosci. 2013;14:44 pubmed publisher
Varvel N, Bhaskar K, Kounnas M, Wagner S, Yang Y, Lamb B, et al. NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease. J Clin Invest. 2009;119:3692-702 pubmed publisher
Delobel P, Lavenir I, Ghetti B, Holzer M, Goedert M. Cell-cycle markers in a transgenic mouse model of human tauopathy: increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1. Am J Pathol. 2006;168:878-87 pubmed
Tizon B, Ribe E, Mi W, Troy C, Levy E. Cystatin C protects neuronal cells from amyloid-beta-induced toxicity. J Alzheimers Dis. 2010;19:885-94 pubmed publisher
Roa W, Zhang X, Guo L, Shaw A, Hu X, Xiong Y, et al. Gold nanoparticle sensitize radiotherapy of prostate cancer cells by regulation of the cell cycle. Nanotechnology. 2009;20:375101 pubmed publisher
Woo Y, Panlilio C, Cheng R, Liao G, Atluri P, Hsu V, et al. Therapeutic delivery of cyclin A2 induces myocardial regeneration and enhances cardiac function in ischemic heart failure. Circulation. 2006;114:I206-13 pubmed
Pascreau G, Eckerdt F, Churchill M, Maller J. Discovery of a distinct domain in cyclin A sufficient for centrosomal localization independently of Cdk binding. Proc Natl Acad Sci U S A. 2010;107:2932-7 pubmed publisher
Wang Q, Liu H, Liu T, Shu S, Jiang H, Cheng S, et al. BRCA2 dysfunction promotes malignant transformation of pancreatic intraepithelial neoplasia. Anticancer Agents Med Chem. 2013;13:261-9 pubmed
Sasaki T, Maier B, Koclega K, Chruszcz M, Gluba W, Stukenberg P, et al. Phosphorylation regulates SIRT1 function. PLoS ONE. 2008;3:e4020 pubmed publisher
Konishi K, Gibson K, Lindell K, Richards T, Zhang Y, Dhir R, et al. Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2009;180:167-75 pubmed publisher
Wang L, Wang R, Herrup K. E2F1 works as a cell cycle suppressor in mature neurons. J Neurosci. 2007;27:12555-64 pubmed
Ramathal C, Bagchi I, Bagchi M. Lack of CCAAT enhancer binding protein beta (C/EBPbeta) in uterine epithelial cells impairs estrogen-induced DNA replication, induces DNA damage response pathways, and promotes apoptosis. Mol Cell Biol. 2010;30:1607-19 pubmed publisher
Varvel N, Bhaskar K, Patil A, Pimplikar S, Herrup K, Lamb B. Abeta oligomers induce neuronal cell cycle events in Alzheimer's disease. J Neurosci. 2008;28:10786-93 pubmed publisher
Murashima Y, Suzuki J, Yoshii M. Cell cycle reentry and cell proliferation as candidates for the seizure predispositions in the hippocampus of EL mouse brain. Epilepsia. 2007;48:119-25 pubmed
product information
Catalog Number :
ab7956
Product Name :
Cyclin A antibody
Host Species :
Rabbit
Clonality :
polyclonal
Product Type :
Primary antibodies
Size :
1 ml
SwissProtID :
P20248
Isotype :
IgG
CrossReactivity :
Reacts with: Human, Mouse, Rat. Does not react with: African Green Monkey.
Application Summary :
ICC/IF, IHC-Fr, IHC-P, IP, WB
company information
Abcam
330 Cambridge Science Park
Cambridge
CB4 0FL UK
orders@abcam.com
44 (0)1223 696000

1 Kendall Square, Ste 341
Cambridge, MA 02139-1517
USA
us.orders@abcam.com
617 225 2272, 888-77-ABCAM (22226)

www.abcam.com
888-7722226
headquarters: UK