This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Ascent Scientific
product type :
antibody
product name :
RNA polymerase II CTD repeat YSPTSPS (phospho S2) antibody [H5] - ChIP Grade
catalog :
ab24758
quantity :
100 ul
clonality :
monoclonal
host :
mouse
antigen modification :
phosphorylated
clone name :
H5
reactivity :
human, mouse, zebrafish , fruit fly
application :
western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
citations: 38
Published Application/Species/DilutionReference
  • immunocytochemistry; human
Kalendová A, Kalasová I, Yamazaki S, Uličná L, Harata M, Hozak P. Nuclear actin filaments recruit cofilin and actin-related protein 3, and their formation is connected with a mitotic block. Histochem Cell Biol. 2014;142:139-52 pubmed publisher
Mannini L, C Lamaze F, Cucco F, Amato C, Quarantotti V, Rizzo I, et al. Mutant cohesin affects RNA polymerase II regulation in Cornelia de Lange syndrome. Sci Rep. 2015;5:16803 pubmed publisher
Fidaleo M, Svetoni F, Volpe E, Minana B, Caporossi D, Paronetto M. Genotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9. Oncotarget. 2015;6:31740-57 pubmed publisher
Koo J, Mazei-Robison M, LaPlant Q, Egervári G, Braunscheidel K, Adank D, et al. Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Nat Neurosci. 2015;18:415-22 pubmed publisher
Matrone G, Wilson K, Maqsood S, Mullins J, Tucker C, Denvir M. CDK9 and its repressor LARP7 modulate cardiomyocyte proliferation and response to injury in the zebrafish heart. J Cell Sci. 2015;128:4560-71 pubmed publisher
White E, Schlackow M, Kamieniarz-Gdula K, Proudfoot N, Gullerova M. Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA. Nat Struct Mol Biol. 2014;21:552-9 pubmed publisher
Paz S, Krainer A, Caputi M. HIV-1 transcription is regulated by splicing factor SRSF1. Nucleic Acids Res. 2014;42:13812-23 pubmed
Vastenhouw N, Zhang Y, Woods I, Imam F, Regev A, Liu X, et al. Chromatin signature of embryonic pluripotency is established during genome activation. Nature. 2010;464:922-6 pubmed publisher
Regnard C, Straub T, Mitterweger A, Dahlsveen I, Fabian V, Becker P. Global analysis of the relationship between JIL-1 kinase and transcription. PLoS Genet. 2011;7:e1001327 pubmed publisher
Sohn B, Park I, Lee J, Yang S, Jang Y, Park K, et al. Functional switching of TGF-beta1 signaling in liver cancer via epigenetic modulation of a single CpG site in TTP promoter. Gastroenterology. 2010;138:1898-908 pubmed publisher
Park I, Sohn B, Yu E, Suh D, Chung Y, Lee J, et al. Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein. Gastroenterology. 2007;132:1476-94 pubmed
Yin P, Lin Z, Reierstad S, Wu J, Ishikawa H, Marsh E, et al. Transcription factor KLF11 integrates progesterone receptor signaling and proliferation in uterine leiomyoma cells. Cancer Res. 2010;70:1722-30 pubmed publisher
Pedrotti S, Busà R, Compagnucci C, Sette C. The RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulator. Nucleic Acids Res. 2012;40:1021-32 pubmed publisher
She W, Grimanelli D, Rutowicz K, Whitehead M, Puzio M, Kotlinski M, et al. Chromatin reprogramming during the somatic-to-reproductive cell fate transition in plants. Development. 2013;140:4008-19 pubmed publisher
Venit T, Dzijak R, Kalendová A, Kahle M, Rohozkova J, Schmidt V, et al. Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus. PLoS ONE. 2013;8:e61406 pubmed publisher
Gao C, Guo H, Mi Z, Grusby M, Kuo P. Osteopontin induces ubiquitin-dependent degradation of STAT1 in RAW264.7 murine macrophages. J Immunol. 2007;178:1870-81 pubmed
Galvão R, Li M, Kothadia S, Haskel J, Decker P, Van Buskirk E, et al. Photoactivated phytochromes interact with HEMERA and promote its accumulation to establish photomorphogenesis in Arabidopsis. Genes Dev. 2012;26:1851-63 pubmed publisher
Rahl P, Lin C, Seila A, Flynn R, McCuine S, Burge C, et al. c-Myc regulates transcriptional pause release. Cell. 2010;141:432-45 pubmed publisher
Kosters A, Sun D, Wu H, Tian F, Felix J, Li W, et al. Sexually dimorphic genome-wide binding of retinoid X receptor alpha (RXRα) determines male-female differences in the expression of hepatic lipid processing genes in mice. PLoS ONE. 2013;8:e71538 pubmed publisher
Gao Z, Liu H, Daxinger L, Pontes O, He X, Qian W, et al. An RNA polymerase II- and AGO4-associated protein acts in RNA-directed DNA methylation. Nature. 2010;465:106-9 pubmed publisher
Garinis G, Uittenboogaard L, Stachelscheid H, Fousteri M, van Ijcken W, Breit T, et al. Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity. Nat Cell Biol. 2009;11:604-15 pubmed publisher
Nestorov P, Battke F, Levesque M, Gerberding M. The maternal transcriptome of the crustacean Parhyale hawaiensis is inherited asymmetrically to invariant cell lineages of the ectoderm and mesoderm. PLoS ONE. 2013;8:e56049 pubmed publisher
Taketo T, Naumova A. Oocyte heterogeneity with respect to the meiotic silencing of unsynapsed X chromosomes in the XY female mouse. Chromosoma. 2013;122:337-49 pubmed publisher
Zhang H, Li L, Papadopoulou N, Hodgson G, Evans E, Galbraith M, et al. Mitogen-induced recruitment of ERK and MSK to SRE promoter complexes by ternary complex factor Elk-1. Nucleic Acids Res. 2008;36:2594-607 pubmed publisher
Mahony S, Mazzoni E, McCuine S, Young R, Wichterle H, Gifford D. Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis. Genome Biol. 2011;12:R2 pubmed publisher
Becherel O, Yeo A, Stellati A, Heng E, Luff J, Suraweera A, et al. Senataxin plays an essential role with DNA damage response proteins in meiotic recombination and gene silencing. PLoS Genet. 2013;9:e1003435 pubmed publisher
Bitler B, Goverdhan A, Schroeder J. MUC1 regulates nuclear localization and function of the epidermal growth factor receptor. J Cell Sci. 2010;123:1716-23 pubmed publisher
Saban M, O'Donnell M, Hurst R, Wu X, Simpson C, Dozmorov I, et al. Molecular networks discriminating mouse bladder responses to intravesical bacillus Calmette-Guerin (BCG), LPS, and TNF-alpha. BMC Immunol. 2008;9:4 pubmed publisher
Albini S, Coutinho P, Malecova B, Giordani L, Savchenko A, Forcales S, et al. Epigenetic reprogramming of human embryonic stem cells into skeletal muscle cells and generation of contractile myospheres. Cell Rep. 2013;3:661-70 pubmed publisher
Tao Y, Xi S, Briones V, Muegge K. Lsh mediated RNA polymerase II stalling at HoxC6 and HoxC8 involves DNA methylation. PLoS ONE. 2010;5:e9163 pubmed publisher
Zhao Y, Ding X, Ye X, Dai Z, Yang J, Yang W. Involvement of cyclin K posttranscriptional regulation in the formation of Artemia diapause cysts. PLoS ONE. 2012;7:e32129 pubmed publisher
Palstra R, Simonis M, Klous P, Brasset E, Eijkelkamp B, de Laat W. Maintenance of long-range DNA interactions after inhibition of ongoing RNA polymerase II transcription. PLoS ONE. 2008;3:e1661 pubmed publisher
Jablonski J, Amelio A, Giacca M, Caputi M. The transcriptional transactivator Tat selectively regulates viral splicing. Nucleic Acids Res. 2010;38:1249-60 pubmed publisher
Busà R, Geremia R, Sette C. Genotoxic stress causes the accumulation of the splicing regulator Sam68 in nuclear foci of transcriptionally active chromatin. Nucleic Acids Res. 2010;38:3005-18 pubmed publisher
Suzuki T, Abe K, Inoue A, Aoki F. Expression of c-MYC in nuclear speckles during mouse oocyte growth and preimplantation development. J Reprod Dev. 2009;55:491-5 pubmed
Naumova A, Fayer S, Leung J, Boateng K, Camerini-Otero R, Taketo T. Dynamics of response to asynapsis and meiotic silencing in spermatocytes from Robertsonian translocation carriers. PLoS ONE. 2013;8:e75970 pubmed publisher
Deng W, Malecova B, OELGESCHLAGER T, Roberts S. TFIIB recognition elements control the TFIIA-NC2 axis in transcriptional regulation. Mol Cell Biol. 2009;29:1389-400 pubmed publisher
Saban R, Saban M, Maier J, Fowler B, Tengowski M, Davis C, et al. Urothelial expression of neuropilins and VEGF receptors in control and interstitial cystitis patients. Am J Physiol Renal Physiol. 2008;295:F1613-23 pubmed publisher
product information
Catalog Number :
ab24758
Product Name :
RNA polymerase II CTD repeat YSPTSPS (phospho S2) antibody [H5] - ChIP Grade
Host Species :
Mouse
Clonality :
monoclonal
AntigenModification :
Phospho
Product Type :
Primary antibodies
Size :
100 ul
SwissProtID :
P24928
Isotype :
IgM
CrossReactivity :
Reacts with: Human, Mouse, Fruit fly (Drosophila melanogaster), Zebrafish. Predicted to react with: a wide range of other species.
Application Summary :
ChIP, FuncS, ICC/IF, IP, P, WB
company information
Abcam
330 Cambridge Science Park
Cambridge
CB4 0FL UK
orders@abcam.com
44 (0)1223 696000

1 Kendall Square, Ste 341
Cambridge, MA 02139-1517
USA
us.orders@abcam.com
617 225 2272, 888-77-ABCAM (22226)

www.abcam.com
888-7722226
headquarters: UK