This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ALPCO
product type :
ELISA/assay
product name :
Monkey TNF-alpha ELISA
catalog :
61-TNAMK-E01
quantity :
96 Wells
price :
700.00 USD
product information
Catalog Number :
61-TNAMK-E01
Product Name :
Monkey TNF-alpha ELISA
List Price :
700.00 USD
Description :
Tumor Necrosis Factor is a polypeptide cytokine produced by monocytes and macrophages. It functions as a multipotent modulator of immune response and further acts as a potent pyrogen. TNF-alpha circulates throughout the body responding to stimuli (infectious agents or tissue injury), activating neutrophils, altering the properties of vascular endothelial cells, regulating metabolic activities of other tissues, as well as exhibiting tumoricidal activity by inducing localized blood clotting. TNF-alpha also inhibits lipoprotein lipase activity resulting in cachexia, a physical wasting condition. Activation of B-cells by the Epstein Barr virus can be inhibited by TNF-alpha. Due to its varied actions throughout the immune system, TNF-alpha may play a role in the pathogenesis of many disease states. TNF-alpha production is mediated by the action of lymphokines and endotoxins on the macrophage. Purified monocytes produce TNF-alpha within four hours of stimulation by recombinant IL-2 and there is some in vitro evidence to suggest that TNF-alpha is expressed at high levels and with prolonged kinetics in T cells stimulated by both CD2 and CD28. Secretion of TNF-alpha is enhanced by gamma interferon. TNF then induces or enhances the specific production of Class I MHC antigen, GM-CSF, and IL-1.
Therapeutic Areas :
Diabetes & Obesity, Immunology
Species :
Non-Human Primate
Sample Types :
Cell Culture, Serum
Size :
96 Wells
Regulatory Status :
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution :
Available Worldwide
Applications :
Immunoassays
Sample Size :
50 µL
Range :
28.1 - 1,800 U/mL
Sensitivity :
6.0 U/mL
Incubation Time :
3hr 10min
company information
ALPCO
26G Keewaydin Drive
Salem, NH 03079
email@alpco.com
http://www.alpco.com
1-603-893-8914
headquarters: USA
ALPCO was founded in 1990 as an importer and distributor of high quality research immunoassay kits. Since that time, their primary goals have been to offer a diverse line of assays that appeal to their broad customer base while also providing exceptional customer service and product support.