This is a Validated Antibody Database (VAD) review about zebrafish sypa, based on 4 published articles (read how Labome selects the articles), using sypa antibody in all methods. It is aimed to help Labome visitors find the most suited sypa antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
sypa synonym: syp; synaptophysin

Synaptic Systems
mouse monoclonal (7.2)
  • western blot; mouse; 1:1000; loading ...; fig 3a
In order to investigate the function of extended synaptotagmins in knock out mice, Synaptic Systems sypa antibody (Synaptic systems, 7.2) was used in western blot on mouse samples at 1:1000 (fig 3a). PLoS ONE (2016) ncbi
mouse monoclonal (7.2)
  • western blot; human
In order to elucidate the mechanisms by which L1CAM gene mutations result in neuronal defects, Synaptic Systems sypa antibody (Synaptic Systems, 7.2) was used in western blot on human samples . J Exp Med (2016) ncbi
mouse monoclonal (7.2)
  • western blot; rat
  • western blot; dog; 1:3000; fig 7
  • western blot; human
In order to study canine cognitive impairment syndrome, Synaptic Systems sypa antibody (Synaptic Systems, 101 011C3) was used in western blot on rat samples , in western blot on dog samples at 1:3000 (fig 7) and in western blot on human samples . J Comp Neurol (2016) ncbi
Abcam
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:250; fig 3
In order to study recapitulation of SCA7 pathology and promotion of accumulation of the FUS/TLS and MBNL1 RNA-binding proteins by lentiviral vector-mediated overexpression of mutant ataxin-7, Abcam sypa antibody (Abcam, ab32594) was used in immunohistochemistry - frozen section on mouse samples at 1:250 (fig 3). Mol Neurodegener (2016) ncbi
Articles Reviewed
  1. Alves S, Marais T, Biferi M, Furling D, Marinello M, El Hachimi K, et al. Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins. Mol Neurodegener. 2016;11:58 pubmed publisher
  2. Sclip A, Bacaj T, Giam L, Sudhof T. Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction. PLoS ONE. 2016;11:e0158295 pubmed publisher
  3. Patzke C, Acuna C, Giam L, Wernig M, Südhof T. Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation. J Exp Med. 2016;213:499-515 pubmed publisher
  4. Smolek T, Madari A, Farbáková J, Kandrac O, Jadhav S, Cente M, et al. Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment. J Comp Neurol. 2016;524:874-95 pubmed publisher