This is a Validated Antibody Database (VAD) review about zebrafish syn1, based on 24 published articles (read how Labome selects the articles), using syn1 antibody in all methods. It is aimed to help Labome visitors find the most suited syn1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
syn1 synonym: si:dkey-90n12.3

Synaptic Systems
guinea-pigs polyclonal
  • immunohistochemistry; mouse; 1:500; loading ...; fig s12c
Synaptic Systems syn1 antibody (Synaptic Systems, 106004) was used in immunohistochemistry on mouse samples at 1:500 (fig s12c). Sci Adv (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse
Synaptic Systems syn1 antibody (Synaptic Systems, 106002) was used in immunohistochemistry on mouse samples . Nature (2021) ncbi
mouse monoclonal (46.1)
  • immunocytochemistry; rat; loading ...
Synaptic Systems syn1 antibody (Synaptic Systems, 106 011C2) was used in immunocytochemistry on rat samples . Sci Adv (2021) ncbi
mouse monoclonal (46.1)
  • immunocytochemistry; rat; loading ...; fig 3b
Synaptic Systems syn1 antibody (SySy, 106-011) was used in immunocytochemistry on rat samples (fig 3b). Proc Natl Acad Sci U S A (2020) ncbi
mouse monoclonal (46.1)
  • immunocytochemistry; mouse; loading ...; fig 2l
Synaptic Systems syn1 antibody (Synaptic Systems, 106001) was used in immunocytochemistry on mouse samples (fig 2l). Neuron (2021) ncbi
mouse monoclonal (46.1)
  • immunocytochemistry; rat; 1:20,000; loading ...; fig 5a
Synaptic Systems syn1 antibody (Synaptic Systems, 106 011) was used in immunocytochemistry on rat samples at 1:20,000 (fig 5a). elife (2020) ncbi
mouse monoclonal (46.1)
  • immunocytochemistry; human; 1:1000; fig 4a
Synaptic Systems syn1 antibody (Synaptic Systems, 106011) was used in immunocytochemistry on human samples at 1:1000 (fig 4a). Brain Sci (2020) ncbi
guinea-pigs polyclonal
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 1b
Synaptic Systems syn1 antibody (Synaptic Systems, 106 004) was used in immunohistochemistry on mouse samples at 1:1000 (fig 1b). Physiol Rep (2020) ncbi
mouse monoclonal (46.1)
  • western blot; mouse; 1:5000; loading ...; fig 4d
Synaptic Systems syn1 antibody (Sysy, 106011) was used in western blot on mouse samples at 1:5000 (fig 4d). elife (2020) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 1b
Synaptic Systems syn1 antibody (SYSY, 106103) was used in immunocytochemistry on human samples (fig 1b). Science (2019) ncbi
mouse monoclonal (46.1)
  • immunocytochemistry; human; 1:500; loading ...; fig 3s2a
Synaptic Systems syn1 antibody (Synaptic Systems, 106 011) was used in immunocytochemistry on human samples at 1:500 (fig 3s2a). elife (2019) ncbi
guinea-pigs polyclonal
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 2c
Synaptic Systems syn1 antibody (Synaptic Systems, 106004) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 2c). J Neurosci (2019) ncbi
guinea-pigs polyclonal
  • immunocytochemistry; rat; 1:500; loading ...; fig 3c
Synaptic Systems syn1 antibody (Synaptic Systems, 106004) was used in immunocytochemistry on rat samples at 1:500 (fig 3c). elife (2019) ncbi
mouse monoclonal (46.1)
  • western blot; mouse; loading ...; fig 6a
Synaptic Systems syn1 antibody (Synaptic Systems, 106 011) was used in western blot on mouse samples (fig 6a). Food Funct (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:4000; fig 3i
Synaptic Systems syn1 antibody (Synaptic Systems, 106 103) was used in western blot on mouse samples at 1:4000 (fig 3i). Nat Commun (2017) ncbi
mouse monoclonal (46.1)
  • western blot; mouse; loading ...; fig 2a
Synaptic Systems syn1 antibody (Synaptic Systems, 106021) was used in western blot on mouse samples (fig 2a). elife (2017) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; rat; loading ...; fig 6b
Synaptic Systems syn1 antibody (Synaptic Systems, 106103) was used in immunocytochemistry on rat samples (fig 6b). J Neurosci (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 3a
  • western blot; mouse; 1:2000; loading ...; fig 1a
In order to evaluate the application of CRISPR/Cas9 system in postmitotic cells, Synaptic Systems syn1 antibody (Synaptic Systems, 106 103) was used in immunohistochemistry on mouse samples at 1:1000 (fig 3a) and in western blot on mouse samples at 1:2000 (fig 1a). J Neurosci Methods (2017) ncbi
mouse monoclonal (46.1)
  • western blot; mouse; 1:1000; fig 3a
Synaptic Systems syn1 antibody (SySy, 106011) was used in western blot on mouse samples at 1:1000 (fig 3a). EMBO Mol Med (2017) ncbi
mouse monoclonal (46.1)
  • immunocytochemistry; mouse; 1:500; fig 6
  • western blot; mouse; 1:1000; fig 2
In order to propose that SALM4 negatively regulates excitatory synapses via inhibition of SALM3-LAR adhesion, Synaptic Systems syn1 antibody (SySy, 106 011) was used in immunocytochemistry on mouse samples at 1:500 (fig 6) and in western blot on mouse samples at 1:1000 (fig 2). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; fig 5
Synaptic Systems syn1 antibody (Synaptic Systems, 106103) was used in immunocytochemistry on human samples (fig 5). J Neurosci (2016) ncbi
mouse monoclonal (46.1)
  • immunocytochemistry; rat; fig 2
In order to study Arf6 and how it regulates cylcing of releasable synaptic vesicles at the hippocampal synapse, Synaptic Systems syn1 antibody (Synaptic Systems, 106 011) was used in immunocytochemistry on rat samples (fig 2). elife (2016) ncbi
mouse monoclonal (46.1)
  • immunohistochemistry; human; 1:500; loading ...; fig 3a
Synaptic Systems syn1 antibody (Synaptic Systems, 106 011) was used in immunohistochemistry on human samples at 1:500 (fig 3a). Methods (2016) ncbi
mouse monoclonal (46.1)
  • western blot; human
In order to determine the the role of GSK3beta in synaptogenesis by comparing rats and fruit flies, Synaptic Systems syn1 antibody (Synaptic Systems, 160 001) was used in western blot on human samples . PLoS ONE (2015) ncbi
Articles Reviewed
  1. Welch G, Boix C, Schmauch E, Davila Velderrain J, Victor M, Dileep V, et al. Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration. Sci Adv. 2022;8:eabo4662 pubmed publisher
  2. Oury J, Zhang W, Leloup N, Koide A, Corrado A, Ketavarapu G, et al. Mechanism of disease and therapeutic rescue of Dok7 congenital myasthenia. Nature. 2021;595:404-408 pubmed publisher
  3. Ivanova D, Dobson K, Gajbhiye A, Davenport E, Hacker D, Ultanir S, et al. Control of synaptic vesicle release probability via VAMP4 targeting to endolysosomes. Sci Adv. 2021;7: pubmed publisher
  4. Cho I, Panzera L, Chin M, Alpizar S, Olveda G, Hill R, et al. The potassium channel subunit Kvβ1 serves as a major control point for synaptic facilitation. Proc Natl Acad Sci U S A. 2020;117:29937-29947 pubmed publisher
  5. Kuijpers M, Kochlamazashvili G, Stumpf A, Puchkov D, Swaminathan A, Lucht M, et al. Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum. Neuron. 2021;109:299-313.e9 pubmed publisher
  6. Oku S, Feng H, Connor S, Toledo A, Zhang P, Zhang Y, et al. Alternative splicing at neuroligin site A regulates glycan interaction and synaptogenic activity. elife. 2020;9: pubmed publisher
  7. Schoepf C, Zeidler M, Spiecker L, Kern G, Lechner J, Kummer K, et al. Selected Ionotropic Receptors and Voltage-Gated Ion Channels: More Functional Competence for Human Induced Pluripotent Stem Cell (iPSC)-Derived Nociceptors. Brain Sci. 2020;10: pubmed publisher
  8. Arias Hervert E, Xu N, Njus M, Murphy G, Hou Y, Williams J, et al. Actions of Rab27B-GTPase on mammalian central excitatory synaptic transmission. Physiol Rep. 2020;8:e14428 pubmed publisher
  9. Zhang R, Liakath Ali K, Sudhof T. Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum. elife. 2020;9: pubmed publisher
  10. Sun A, Yuan Q, Fukuda M, Yu W, Yan H, Lim G, et al. Potassium channel dysfunction in human neuronal models of Angelman syndrome. Science. 2019;366:1486-1492 pubmed publisher
  11. Ghatak S, Dolatabadi N, Trudler D, Zhang X, Wu Y, Mohata M, et al. Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs isogenic controls. elife. 2019;8: pubmed publisher
  12. Dierich M, Hartmann S, Dietrich N, Moeser P, Brede F, Johnson Chacko L, et al. β-Secretase BACE1 Is Required for Normal Cochlear Function. J Neurosci. 2019;39:9013-9027 pubmed publisher
  13. Rademacher N, Kuropka B, Kunde S, Wahl M, Freund C, Shoichet S. Intramolecular domain dynamics regulate synaptic MAGUK protein interactions. elife. 2019;8: pubmed publisher
  14. Cicvaric A, Bulat T, Bormann D, Yang J, Auer B, Milenkovic I, et al. Sustained consumption of cocoa-based dark chocolate enhances seizure-like events in the mouse hippocampus. Food Funct. 2018;9:1532-1544 pubmed publisher
  15. Lüningschrör P, Binotti B, Dombert B, Heimann P, Pérez Lara A, Slotta C, et al. Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease. Nat Commun. 2017;8:678 pubmed publisher
  16. Daniel J, Cooper B, Palvimo J, Zhang F, Brose N, Tirard M. Analysis of SUMO1-conjugation at synapses. elife. 2017;6: pubmed publisher
  17. Efimova N, Korobova F, Stankewich M, Moberly A, Stolz D, Wang J, et al. ?III Spectrin Is Necessary for Formation of the Constricted Neck of Dendritic Spines and Regulation of Synaptic Activity in Neurons. J Neurosci. 2017;37:6442-6459 pubmed publisher
  18. Horvath P, Kavalali E, Monteggia L. CRISPR/Cas9 system-mediated impairment of synaptobrevin/VAMP function in postmitotic hippocampal neurons. J Neurosci Methods. 2017;278:57-64 pubmed publisher
  19. Sambri I, D Alessio R, Ezhova Y, Giuliano T, Sorrentino N, Cacace V, et al. Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases. EMBO Mol Med. 2017;9:112-132 pubmed publisher
  20. Lie E, Ko J, Choi S, Roh J, Cho Y, Noh R, et al. SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion. Nat Commun. 2016;7:12328 pubmed publisher
  21. Rooney G, Goodwin A, Depeille P, Sharir A, Schofield C, Yeh E, et al. Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome. J Neurosci. 2016;36:142-52 pubmed publisher
  22. Tagliatti E, Fadda M, Falace A, Benfenati F, Fassio A. Arf6 regulates the cycling and the readily releasable pool of synaptic vesicles at hippocampal synapse. elife. 2016;5: pubmed publisher
  23. Ho S, Hartley B, TCW J, Beaumont M, Stafford K, Slesinger P, et al. Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells. Methods. 2016;101:113-24 pubmed publisher
  24. Cuesto G, Jordán Álvarez S, Enriquez Barreto L, Ferrús A, Morales M, Acebes A. GSK3β inhibition promotes synaptogenesis in Drosophila and mammalian neurons. PLoS ONE. 2015;10:e0118475 pubmed publisher