This is a Validated Antibody Database (VAD) review about zebrafish cox4i1, based on 127 published articles (read how Labome selects the articles), using cox4i1 antibody in all methods. It is aimed to help Labome visitors find the most suited cox4i1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
cox4i1 synonym: mg:bb02d03; zgc:110058; cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Cox4-1
Invitrogen
mouse monoclonal (20E8C12) |
| Invitrogen cox4i1 antibody (Life Technologies, A21348) was used in western blot on human samples at 1:500 (fig 1b). Stem Cells (2017) ncbi |
mouse monoclonal (20E8C12) |
| In order to identify posttranscriptional mechanisms that regulate mitochondrial protein expression, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on mouse samples (fig 6b). J Cell Biol (2017) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to elucidate the mechanism regulating GAPDH aggregate-induced cell death, Invitrogen cox4i1 antibody (Invitrogen, 1D6E1A8) was used in western blot on human samples at 1:1000 (fig 2a). J Biol Chem (2017) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to elucidate a novel pathway for mitochondrial elimination, in which these organelles undergo Parkin-dependent sequestration into Rab5-positive early endosomes via the ESCRT machinery, Invitrogen cox4i1 antibody (Life Technologies, 459600) was used in immunocytochemistry on mouse samples at 1:100 (fig 2a). Nat Commun (2017) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to discover that protein oxidative and glycoxidative damage significantly increases during human brain aging, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on human samples at 1:1000 (fig 2). Free Radic Biol Med (2017) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to clarify the role of m-AAA protease in adult glial cells, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in immunohistochemistry - free floating section on mouse samples at 1:1000 (fig 6a). PLoS Genet (2016) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to test if increased submaximal force induced by nitrate supplementation reduces the effort of submaximal voluntary running, Invitrogen cox4i1 antibody (Invitrogen, 459,600) was used in western blot on mouse samples (fig 3b). Physiol Behav (2017) ncbi |
mouse monoclonal (20E8C12) |
| In order to explore how caveolin-1 contributes to mitochondrial integrity and function, Invitrogen cox4i1 antibody (Thermo Fisher, A21348) was used in western blot on mouse samples (fig 5c). Aging (Albany NY) (2016) ncbi |
mouse monoclonal (20E8C12) |
| In order to clarify the role of denervation in modulating mitochondrial function in ageing muscle, Invitrogen cox4i1 antibody (Life Technologies, A21348) was used in western blot on human samples at 1:1000 (fig 5e). J Physiol (2016) ncbi |
mouse monoclonal (20E8C12) |
| In order to use a mitochondrial single-channel patch clamp and cyclophilin D-deficient mice with streptozotocin-induced diabetes to study mitochondrial dysfunction, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on mouse samples (fig 3d). Diabetes (2016) ncbi |
mouse monoclonal (20E8C12) |
| In order to characterize a mouse model of MICU1 deficiency, Invitrogen cox4i1 antibody (Life Technologies, A21348) was used in western blot on mouse samples (fig 5c). Cell Rep (2016) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study alleviation of impaired mitochondrial biogenesis by twinkle overexpression preventing cardiac rupture after myocardial infarction, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on mouse samples (fig 6). Am J Physiol Heart Circ Physiol (2016) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study placental mammal-specific mitochondrial pyruvate carrier subunit called MPC1-like and its expression in post-meiotic male germ cells, Invitrogen cox4i1 antibody (Thermo Scientific, 459600) was used in immunohistochemistry - frozen section on mouse samples (fig 7). J Biol Chem (2016) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to research the conversion to a pro-apoptotic protein mimicking Bax/Bak by Cdk2 phosphorylation of Bcl-xL after stress, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on mouse samples (fig S2). Cell Death Discov (2016) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study the alleviation of mitochondrial cardiomyopathy without affecting the mammalian UPRmt due to loss of CLPP, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on mouse samples at 1:1000 (fig 3). EMBO Rep (2016) ncbi |
mouse monoclonal (20E8C12) |
| In order to study the alleviation of mitochondrial cardiomyopathy without affecting the mammalian UPRmt due to loss of CLPP, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on mouse samples at 1:1000 (fig 3). EMBO Rep (2016) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study muscular dystrophy and the downstream effects of plectin mutations in epidermolysis bullosa simplex, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in immunohistochemistry - frozen section on human samples (fig 4). Acta Neuropathol Commun (2016) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to determine the role of mitophagy in apoptosis induced by oxidized low-density lipoproteins using human vascular smooth muscle cells, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on human samples (fig 3d). Oncotarget (2016) ncbi |
mouse monoclonal (20E8C12) |
| In order to study the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome and mitochondrial-targeted aryl hydrocarbon receptor, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on mouse samples (fig 1). Toxicol Appl Pharmacol (2016) ncbi |
mouse monoclonal (20E8C12) |
| In order to mediate direct uptake of RNA by lysosomes by lysosomal putative RNA transporter SIDT2, Invitrogen cox4i1 antibody (Life Technologies, 20E8C12) was used in western blot on mouse samples (fig 1). Autophagy (2016) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study how a monoclonal antibody against bacterially expressed MPV17 sequences show lysosomal, endosomal, and peroxisomal localization in U20S cells, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in immunocytochemistry on human samples at 1:200 (fig 2). BMC Res Notes (2016) ncbi |
mouse monoclonal (20E8C12) |
| In order to characterize macrophage polarization with fatty acid oxidation, Invitrogen cox4i1 antibody (Thermo Scientific, A21348) was used in western blot on mouse samples at 1:2000 (fig 1). Nat Immunol (2016) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study how OMA1 links mitochondrial morphology and cardiac metabolism, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on mouse samples (fig s3a). Science (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to analyze delay of neurodegeneration by preventing stress-induced OPA1 processing in mitochondria by loss of OMA1, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on mouse samples (fig 5). J Cell Biol (2016) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study SNAP23 and colocalization with lipid droplets, mitochondria, and plasma membrane in human skeletal muscle by immunofluorescence microscopy, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in immunohistochemistry - frozen section on human samples at 1:50 (fig 3). Physiol Rep (2016) ncbi |
mouse monoclonal (20E8C12) |
| In order to investigate how lactate affects neuron metabolism, Invitrogen cox4i1 antibody (Life Technologies, A21348) was used in western blot on human samples at 1:2000 (fig 7). Biochem Pharmacol (2016) ncbi |
mouse monoclonal (20E8C12) |
| In order to discuss the role of autophagy in cell death, Invitrogen cox4i1 antibody (Molecular Probes, A21348) was used in western blot on human samples . Biochem Pharmacol (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to elucidate the role of AMPKalpha1 and -alpha2 subunits in acute exercise-induced mRNA responses, Invitrogen cox4i1 antibody (Invitrogen, #459600) was used in western blot on mouse samples . Am J Physiol Endocrinol Metab (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to characterize the effect of cyclosporine A treatment in a mouse model of lethal mitochondrial myopathy, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on human samples . Hum Mol Genet (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to demonstrate that a lack of ezrin causes achlorhydria and hypergastrinemia, Invitrogen cox4i1 antibody (Camarillo, 1D6E1A8) was used in immunohistochemistry - paraffin section on mouse samples (fig 8). J Physiol Sci (2016) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to assess the genetic variation of SLC30A2 associated with breast cell dysfunction, Invitrogen cox4i1 antibody (Invitrogen, #459600) was used in immunocytochemistry on mouse samples (fig s4). J Mammary Gland Biol Neoplasia (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to test if mitochondrial proteins can be used as biomarkers for primary biliary cirrhosis, Invitrogen cox4i1 antibody (Invitrogen, 1D6E1A8) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1). Virchows Arch (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to assess the effect of PINK1-deficiency on mitochondrial quality control in myocytes, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in immunocytochemistry on mouse samples at 1:1000 and in western blot on mouse samples at 1:1000. PLoS ONE (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to report how the depletion of distinct plectin isoforms differentially affects mitochondrial network organization and function, Invitrogen cox4i1 antibody (Invitrogen, 1D6E1A8) was used in western blot on mouse samples (fig 2). Hum Mol Genet (2015) ncbi |
mouse monoclonal (20E8C12) |
| In order to test the effects of mechanical overloading using a murine model of Duchene muscular dystrophy, Invitrogen cox4i1 antibody (Life Technologies, A21348) was used in western blot on mouse samples . Am J Pathol (2015) ncbi |
rabbit monoclonal (K.473.4) |
| In order to study the role of nuclear CLK-1 in regulating mitochondrial stress responses and aging, Invitrogen cox4i1 antibody (Pierce, MA5-15078) was used in western blot on human samples at 1:2000 (fig 6). Nat Cell Biol (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study the role of nuclear CLK-1 in regulating mitochondrial stress responses and aging, Invitrogen cox4i1 antibody (Life Technologies, 459600) was used in western blot on human samples at 1:2000 (fig 6). Nat Cell Biol (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to develop a flow cytometry-based approach to study mitophagy by using MitoTracker Deep Red, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on mouse samples (fig 1, 6). Autophagy (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to test the requirement of AMP-activated protein kinase for exercise training-induced increases in skeletal muscle abundance of mitochondrial proteins, Invitrogen cox4i1 antibody (Invitrogen, #459600) was used in western blot on mouse samples . Front Physiol (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to test if endoscopically normal appearing colonic mucosa in patients with UC in remission have fully recovered using confocal laser endomicroscopy, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in immunohistochemistry - paraffin section on human samples at 1:100. J Gastroenterol Hepatol (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to assess the role of mtDNA copy number in heart failure, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on mouse samples . PLoS ONE (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to discuss the role of CD47 modulation in treatment of chronic lymphocytic leukemia, Invitrogen cox4i1 antibody (Life Technologies, 1D6E1A8) was used in western blot on human samples . PLoS Med (2015) ncbi |
rabbit monoclonal (K.473.4) |
| In order to test if 3,5-Diiodo-l-thyronine could activate brown adipose tissue thermogenesis, Invitrogen cox4i1 antibody (Thermo Scientific, MA5-15078) was used in immunohistochemistry - paraffin section on rat samples at 1:250. PLoS ONE (2015) ncbi |
mouse monoclonal (20E8C12) |
| In order to demonstrate that altered/impaired expression of mtDNA induces CHOP-10 expression dependent on the eIF2alpha/ATF4 axis of the integrated stress response, Invitrogen cox4i1 antibody (Life Technologies, A21348) was used in western blot on human samples . Mitochondrion (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to use an evolutionary approach to identify putative modifying factors involved in aminoglycoside-induced and non-syndromic hearing loss, Invitrogen cox4i1 antibody (Life Technologies, 459600) was used in western blot on human samples at 1:1000. Front Genet (2014) ncbi |
mouse monoclonal (20E8C12) |
| In order to investigate the role of Fsp27 in adipose inflammation and hepatic insulin resistance, Invitrogen cox4i1 antibody (Molecular Probes, A21348) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2015) ncbi |
mouse monoclonal (20E8C12) |
| In order to investigate the role of mitochondria-associated miRNAs in traumatic brain injury, Invitrogen cox4i1 antibody (Life Technologies Inc, A21348) was used in western blot on rat samples at 1:200000. Exp Neurol (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to examine the contribution of the mitochondrial Ca(2+) uniporter to the regulation of oxidative phosphorylation and metabolism-secretion coupling in beta-cells and rat pancreatic islets, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on rat samples at 1:1000. J Biol Chem (2015) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study endonuclease G-mediated cleavage of 5hmC-modified DNA, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on mouse samples at 1 ug/ml (fig s1). Nucleic Acids Res (2014) ncbi |
mouse monoclonal (20E8C12) |
| In order to study the role of down syndrome cell adhesion molecule during mice retina development, Invitrogen cox4i1 antibody (Life Technologies, A21348) was used in immunohistochemistry on mouse samples at 1:750. Mol Vis (2014) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study GRAF1a that promotes lipid droplet clustering and growth and its enrichment at lipid droplet junctions, Invitrogen cox4i1 antibody (Life technologies, 1D6E1A8) was used in immunocytochemistry on human samples (fig s1). J Cell Sci (2014) ncbi |
mouse monoclonal (20E8C12) |
| In order to test if constitutive activation of SIRT1 in skeletal muscle prevents high fat diet-induced muscle insulin resistance, Invitrogen cox4i1 antibody (Life Technologies, A21348) was used in western blot on mouse samples . Am J Physiol Endocrinol Metab (2014) ncbi |
mouse monoclonal (20E8C12) |
| In order to study the effect of perinatal protein malnutrition on mitochondrial function and obesity in adults, Invitrogen cox4i1 antibody (Molecular probes, A21348) was used in western blot on mouse samples at 1:1000. PLoS ONE (2014) ncbi |
mouse monoclonal (20E8C12) |
| In order to describe mitochondrial biogenesis during hepatogenic differentiation of bone marrow-mesenchymal stem cells, Invitrogen cox4i1 antibody (Life Technologies, A21348) was used in western blot on human samples at 1:500 (fig s1). Int J Biochem Cell Biol (2014) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to determine the mechanisms underlying the decrease in hepatic cytochrome P-450 during ascorbic acid deficiency using scurvy-prone ODS rats, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on rat samples at 1:1000. Biosci Biotechnol Biochem (2014) ncbi |
mouse monoclonal (20E8C12) |
| In order to determine how intensive exercise affects brain bioenergetics, inflammation, and neurogenesis-relevant parameters, Invitrogen cox4i1 antibody (Life Technologies, A21348) was used in western blot on mouse samples at 1:2000. Neurobiol Aging (2014) ncbi |
mouse monoclonal (20E8C12) |
| In order to assess the role of Parkin against cardiotoxicity elicited by arsenic trioxide exposure in HL-1 mouse atrial cardiomyocytes, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on mouse samples . Toxicology (2014) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study how autophagy in memory B cells regulates vaccine responses, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in immunocytochemistry on mouse samples (fig s12b). Nat Med (2014) ncbi |
mouse monoclonal (20E8C12) |
| In order to study the effect of O-GlcNAc cycling in mitochondria, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on human samples at 1:1000. J Biol Chem (2014) ncbi |
mouse monoclonal (20E8C12) |
| In order to generate tools to assess mitochondrial health in vivo, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in immunohistochemistry - paraffin section on mouse samples at 1:100, in immunocytochemistry on mouse samples (fig 1) and in western blot on mouse samples . J Biol Chem (2014) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to compare the effects of Roux-en Y gastric bypass and ileal transposition surgeries on glucose and lipid metabolism in muscle and liver, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on rat samples at 1:1000 (fig 3). Surg Obes Relat Dis (2014) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to compare the effect of exercise training and resveratrol treatment on metabolic and inflammatory status in skeletal muscle of aged men, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on human samples . J Physiol (2014) ncbi |
mouse monoclonal (20E8C12) |
| In order to define the aryl-hydrocarbon receptor-protein interaction network, Invitrogen cox4i1 antibody (Life Technologies, A21348) was used in western blot on mouse samples (fig 7). J Toxicol (2013) ncbi |
mouse monoclonal (20E8C12) |
| In order to study the relationship between USP2-MDM4 and p53 in tumorigenesis, Invitrogen cox4i1 antibody (Molecular Probes-Invitrogen, A21348) was used in western blot on human samples . Carcinogenesis (2014) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study the effects on rat cardiac mitochondrial oxidative stress of simultaneous treatment with atenolol plus methionine restriction, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on rat samples at 1:500 (fig 3). J Bioenerg Biomembr (2014) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study the role of mitochochondrial Nox4 upregulation in the induction of cultured murine podicyte apoptosis by TGF-beta, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in immunocytochemistry on mouse samples at 5 ug/ml (fig 3). Am J Physiol Renal Physiol (2014) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to test if and how MsrA affects retinal pigment epithelium functionality, Invitrogen cox4i1 antibody (Invitrogen, clone 1D6E1A8) was used in western blot on rat samples (fig 9). Free Radic Biol Med (2013) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to elucidate the mechanisms underlying cellular damage and senescence and accelerated aging in Hutchinson-Gilford progeria syndrome, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on mouse samples (fig 2). J Proteomics (2013) ncbi |
mouse monoclonal (20E8C12) |
| In order to study the involvement of PARL and HtrA2 in striatal neuronal injury after transient global cerebral ischemia, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on mouse samples at 1:2,000. J Cereb Blood Flow Metab (2013) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study oxidative stress in the retinal pigment epithelium (RPE) regulated by DJ-1, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in immunocytochemistry on human samples at 1:500 (fig 3). PLoS ONE (2013) ncbi |
mouse monoclonal (20E8C12) |
| In order to test if STARS influences C2C12 myotube growth by regulating protein synthesis and degradation, Invitrogen cox4i1 antibody (Life Technologies, A21348) was used in western blot on mouse samples at 1:10000 (fig 4). Am J Physiol Cell Physiol (2013) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to examine the effects of NaHCO3 on myogenesis, Invitrogen cox4i1 antibody (Invitrogen, clone 1D6E1A8) was used in immunocytochemistry on human samples at 1:200 (fig 3). Am J Physiol Cell Physiol (2013) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study the localization of a GRSF1 isoform to the mitochondrial matrix and its role in RNA processing, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on human samples (fig 3). Cell Metab (2013) ncbi |
mouse monoclonal (20E8C12) |
| In order to test if the increases in PGC-1alpha and mitochondrial biogenesis induced by endurance exercise are mediated by catecholamines, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on mouse samples (fig 2). Am J Physiol Endocrinol Metab (2013) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to investigate the effect of metformin treatment on mitochondrial respiration in mouse skeletal muscle, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on mouse samples . PLoS ONE (2013) ncbi |
mouse monoclonal (20E8C12) |
| In order to determine the role of sirtuin 1 in exercise- and resveratrol-induced skeletal muscle mitochondrial biogenesis, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on mouse samples at 1:1000 (fig 3). J Biol Chem (2013) ncbi |
mouse monoclonal (20E8C12) |
| In order to study the contribution of PINK1 to mitochondrial function/dynamics, Invitrogen cox4i1 antibody (Molecular Probes, A21348) was used in western blot on mouse samples (fig 5). Neurodegener Dis (2013) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to investigate the effects of endurance training on intramuscular triglyceride utilization, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in immunohistochemistry - frozen section on human samples . J Physiol (2013) ncbi |
mouse monoclonal (20E8C12) |
| In order to study the effect of different inhibitors on mitochondrial permeability transition pore, Invitrogen cox4i1 antibody (Molecular Probes, A21348) was used in western blot on mouse samples (fig 2). Biochim Biophys Acta (2012) ncbi |
mouse monoclonal (20E8C12) |
| In order to question the expression and function of ABCB6 in the mitochondria, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on human samples . PLoS ONE (2012) ncbi |
mouse monoclonal (20E8C12) |
| In order to examine the effects of exercise on liver and brain bioenergetic infrastructures, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on mouse samples at 1:2000 (fig 11). Exp Physiol (2013) ncbi |
mouse monoclonal (20E8C12) |
| In order to test if the malignant hyperthermia model mice are more vulnerable to exercise-induced muscle injury and fatigability, Invitrogen cox4i1 antibody (Molecular Probes, A21348) was used in western blot on mouse samples at 1:800 (fig 4). Muscle Nerve (2012) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study the greater activation of phosphorylation pathways in human gastrocnemius as compared to soleus muscle when normalized for EMG activity, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on human samples (fig 2). PLoS ONE (2012) ncbi |
mouse monoclonal (20E8C12) |
| In order to describe a method to label severely injured or soft newborn brains using rodents, Invitrogen cox4i1 antibody (Molecular Probes, #A21348) was used in western blot on mouse samples (fig 3). J Neurosci Methods (2012) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to test the requirement of formylation for initiation in human mitochondria, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on human samples (fig 2). Cell Metab (2011) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to identify molecules involved in sperm-zona pellucida interactions, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on mouse samples (fig s1). J Biol Chem (2011) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to determine the enzymatic function of FAHD1, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in immunocytochemistry on human samples (fig 8). J Biol Chem (2011) ncbi |
mouse monoclonal (20E8C12) |
| In order to determine the effects of rotenone treatment in the retina, Invitrogen cox4i1 antibody (Molecular Probes, A21348) was used in immunohistochemistry on rat samples at 1:1000 (fig 8). Neurobiol Dis (2011) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to investigate the effects of mitochondrial DNA damage on hippocampal neurons, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 1). DNA Repair (Amst) (2011) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study the effects of the m.1630A G mutation in the mitochondrial tRNA gene, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on human samples (fig 6). Mitochondrion (2011) ncbi |
mouse monoclonal (20E8C12) |
| In order to investigate the role of PGC-1alpha in organelle biogenesis, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on mouse samples at 1:500 (fig 1). Am J Physiol Endocrinol Metab (2011) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to examine the tissue distribution of SCO1 and SCO2, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on human samples at 1:400 (fig 1). Am J Pathol (2010) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to investigate the differences of proton conductance mechanism between skeletal muscle and heart, Invitrogen cox4i1 antibody (Invitrogen, 459600) was used in western blot on mouse samples at 1:5000 (fig 2). Biochim Biophys Acta (2010) ncbi |
mouse monoclonal (20E8C12) |
| In order to investigate genetic variability of cytochrome oxidase, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on human samples at 0.5 ug/ml (fig 4). J Alzheimers Dis (2010) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to study the mitochondrial targeting sequence of apurinic/apyrimidinic endonuclease, Invitrogen cox4i1 antibody (Molecular Probes, 459600) was used in western blot on human samples at 1:1000 (fig 7). J Biol Chem (2010) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to investigate dexamethasone-induced apoptosis, Invitrogen cox4i1 antibody (Invitrogen, 1D6E1A8) was used in western blot on human samples (fig 6). Biochim Biophys Acta (2010) ncbi |
mouse monoclonal (20E8C12) |
| In order to observe and characterize mitochondria in the rat adrenal gland, Invitrogen cox4i1 antibody (Molecular Probes, A-21348) was used in immunohistochemistry - paraffin section on rat samples and in western blot on rat samples at 1:1000. Acta Histochem (2011) ncbi |
mouse monoclonal (20E8C12) |
| In order to elucidate how angiomotin expression is regulated in vivo, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on rat samples (fig 2). J Physiol (2009) ncbi |
mouse monoclonal (20E8C12) |
| In order to study AMPK activation and its regulation of cell surface GLUT3 expression in neuronal tolerance to excitotoxicity, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on rat samples at 1:100 (fig 1d). J Neurosci (2009) ncbi |
mouse monoclonal (20E8C12) |
| In order to test if cGMP rescues mitochondrial dysfunction in C2C12 myotubular cells induced high-glucose and high-insulin conditions, Invitrogen cox4i1 antibody (Molecular Probes, A21348) was used in western blot on mouse samples at 1:1000 (fig 3). Biochem Biophys Res Commun (2008) ncbi |
mouse monoclonal (20E8C12) |
| In order to test if protection from heart I/R damage by P-alphaBC-S59 is mediated by its localization to mitochondria, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on mouse samples (fig 1). Am J Physiol Heart Circ Physiol (2008) ncbi |
mouse monoclonal (20E8C12) |
| In order to study the apoptotic responses associated with soleus muscle atrophy and subsequent recovery, Invitrogen cox4i1 antibody (Molecular Probes, A21348) was used in western blot on rat samples at 1:500. Acta Physiol (Oxf) (2008) ncbi |
mouse monoclonal (20E8C12) |
| In order to characterize oxygen tolerance and cytochrome C oxidase activity, Invitrogen cox4i1 antibody (Molecular Probes, noca) was used in western blot on human samples at 1:1000 (fig 1). J Biol Chem (2007) ncbi |
mouse monoclonal (20E8C12) |
| In order to study the pathological consequences of combined ischemia-hypoxia, Invitrogen cox4i1 antibody (Molecular Probes, A21348) was used in western blot on mouse samples (fig 6). Am J Pathol (2006) ncbi |
mouse monoclonal (20E8C12) |
| In order to elucidate how the mitochondrial p53 pathway mediates neuronal apoptosis after cerebral ischemia, Invitrogen cox4i1 antibody (Invitrogen, A21348) was used in western blot on rat samples at 1:5000. J Neurosci (2006) ncbi |
mouse monoclonal (20E8C12) |
| In order to analyze induction of apoptosis in colon cancer cells by PUMA dissociating Bcl-X(L) and Bax, Invitrogen cox4i1 antibody (Molecular Probes, noca) was used in western blot on human samples . J Biol Chem (2006) ncbi |
mouse monoclonal (20E8C12) |
| In order to identify a novel mTOR-independent pathway that regulates autophagy, Invitrogen cox4i1 antibody (Molecular Probes, A-21348) was used in western blot on African green monkey samples . J Cell Biol (2005) ncbi |
mouse monoclonal (20E8C12) |
| In order to investigate the role of the p53 and JNK/c-Jun pathways in the activation of BH3-only proteins, Invitrogen cox4i1 antibody (Molecular Probes, A21348) was used in western blot on mouse samples at 1:500 (fig 3). Mol Cell Biol (2005) ncbi |
mouse monoclonal (20E8C12) |
| In order to examine the effects of soy isoflavones on markers of neuronal apoptosis and survival in vivo, Invitrogen cox4i1 antibody (Molecular Probes, A21348) was used in western blot on rat samples at 0.1 ug/ml. Neurosci Lett (2005) ncbi |
mouse monoclonal (20E8C12) |
| In order to investigate the interaction of tissue transglutaminase with proteins that regulate apoptosis, Invitrogen cox4i1 antibody (Molecular Probes, 20E8-C12) was used in western blot on human samples (fig 2). J Biol Chem (2004) ncbi |
mouse monoclonal (20E8C12) |
| In order to investigate the signaling pathways that regulate cerebellar granule neuron cell death, Invitrogen cox4i1 antibody (Molecular Probes, A21348) was used in western blot on rat samples (fig 7). J Biol Chem (2004) ncbi |
mouse monoclonal (20E8C12) |
| In order to assess the contribution to mitochondrial cytochrome C release and cristae reorganization by Bid-cardiolipin interaction at mitochondrial contact site, Invitrogen cox4i1 antibody (Molecular Probes, 20E8-C12) was used in western blot on mouse samples (fig 2). Mol Biol Cell (2004) ncbi |
mouse monoclonal (20E8C12) |
| In order to test if there are changes in cardiac mitochondrial content and caspase activation during sepsis, Invitrogen cox4i1 antibody (Molecular Probes, A21348) was used in western blot on rat samples (fig 5). J Mol Cell Cardiol (2004) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to investigate the localization and function of CLIC4, Invitrogen cox4i1 antibody (Molecular Probes, 1D6-E1-A8) was used in immunocytochemistry on human samples and in immunocytochemistry on African green monkey samples (tbl 1). Cell Motil Cytoskeleton (2003) ncbi |
mouse monoclonal (20E8C12) |
| In order to study protection of oligodendrocytes from death by regulating Bad through phosphatidylinositol 3-kinase/Akt pathway due to C5b-9 terminal complement complex, Invitrogen cox4i1 antibody (Molecular Probes, noca) was used in western blot on rat samples . J Immunol (2001) ncbi |
mouse monoclonal (20E8C12) |
| In order to elucidate how proteasome inhibitors induce apoptosis in human malignant glioma cells, Invitrogen cox4i1 antibody (Molecular Probes, noca) was used in western blot on human samples (fig 7). J Neurochem (2000) ncbi |
mouse monoclonal (20E8C12) |
| In order to elucidate how Akt or Bcl-2 inhibit apoptosis of hybrid motor neuron 1 cells, Invitrogen cox4i1 antibody (Molecular Probes, 20E8-C12) was used in western blot on mouse samples . J Cell Biol (2000) ncbi |
mouse monoclonal (20E8C12) |
| In order to examine the function of c-Myc in hepatocyte sensitivity to tumor necrosis factor, Invitrogen cox4i1 antibody (Molecular Probes, noca) was used in western blot on rat samples at 1:1000. J Biol Chem (2000) ncbi |
mouse monoclonal (20E8C12) |
| In order to elucidate how reactive oxygen species and cytochrome c contribute to neurotoxicity, Invitrogen cox4i1 antibody (Molecular Probes, 20E8-C12) was used in western blot on rat samples (fig 1A). J Biol Chem (2000) ncbi |
mouse monoclonal (20E8C12) |
| In order to test if mitochondrial protein biosynthesis occurs on ribosomes associated with the inner membrane, Invitrogen cox4i1 antibody (Molecular Probes, 20E8-C12) was used in ELISA on cow samples (fig 1). J Biol Chem (2000) ncbi |
mouse monoclonal (20E8C12) |
| In order to characterize patients with cytochrome c oxidase deficiency, Invitrogen cox4i1 antibody (noco, noca) was used in western blot on human samples (fig 1). Biochim Biophys Acta (1999) ncbi |
mouse monoclonal (20E8C12) |
| In order to report that PGC-1 stimulates mitochondrial biogenesis and respiration in muscle cells via uncoupling protein 2 and nuclear respiratory factors, Invitrogen cox4i1 antibody (Molecular Probes, noca) was used in western blot on mouse samples at 10 ng/ml (fig 2B). Cell (1999) ncbi |
mouse monoclonal (20E8C12) |
| In order to elucidate the mechanisms that regulate cycloheximide-induced apoptosis, Invitrogen cox4i1 antibody (Molecular Probes, 20E8-C12) was used in western blot on human samples (fig 2). J Biol Chem (1999) ncbi |
mouse monoclonal (20E8C12) |
| In order to show that Bid relays an apoptotic signal from the cell surface to mitochondria, Invitrogen cox4i1 antibody (Molecular Probes, noca) was used in western blot on mouse samples . Cell (1998) ncbi |
mouse monoclonal (20E8C12) |
| In order to propose that Bcl-xL promotes cell survival by regulating the electrical and osmotic homeostasis of mitochondria, Invitrogen cox4i1 antibody (Molecular Probes, 20E8-C12) was used in flow cytometry on mouse samples (fig 2B), in western blot on mouse samples at 10 ng/ml (fig 1C) and in western blot on human samples at 10 ng/ml (fig 1A). Cell (1997) ncbi |
mouse monoclonal (20E8C12) |
| In order to characterize a child with mitochondrial DNA depletion in the liver and skeletal muscles, Invitrogen cox4i1 antibody (Molecular Probes, noca) was used in western blot on human samples (fig 4). Hum Mol Genet (1997) ncbi |
mouse monoclonal (1D6E1A8) |
| In order to Mammalian cytochrome-c oxidase: characterization of enzyme and immunological detection of subunits in tissue extracts and whole cells, Invitrogen cox4i1 antibody (Molecular Probes, 1D6-E1-A8) was used in western blot on human samples and in western blot on cow samples . Methods Enzymol (1995) ncbi |
mouse monoclonal (20E8C12) |
| In order to Mammalian cytochrome-c oxidase: characterization of enzyme and immunological detection of subunits in tissue extracts and whole cells, Invitrogen cox4i1 antibody (Molecular Probes, 20E8-CI2) was used in western blot on human samples (fig 3) and in western blot on cow samples (fig 3). Methods Enzymol (1995) ncbi |
mouse monoclonal (20E8C12) |
| In order to review and discuss the mitochondrial respiratory chain, Invitrogen cox4i1 antibody (noco, noca) was used in immunohistochemistry on cow samples (fig 1). J Bioenerg Biomembr (1988) ncbi |
Abcam
mouse monoclonal (mAbcam33985) |
| Abcam cox4i1 antibody (Abcam, ab62164) was used in western blot on human samples (fig 2e). Oncotarget (2016) ncbi |
Articles Reviewed
- Wanet A, Caruso M, Domelevo Entfellner J, Najar M, Fattaccioli A, Demazy C, et al. The Transcription Factor 7-Like 2-Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Axis Connects Mitochondrial Biogenesis and Metabolic Shift with Stem Cell Commitment to Hepatic Differentiation. Stem Cells. 2017;35:2184-2197 pubmed publisher
- Yan S, Du F, Wu L, Zhang Z, Zhong C, Yu Q, et al. F1F0 ATP Synthase-Cyclophilin D Interaction Contributes to Diabetes-Induced Synaptic Dysfunction and Cognitive Decline. Diabetes. 2016;65:3482-3494 pubmed
- Megyesi J, Tarcsafalvi A, Seng N, Hodeify R, Price P. Cdk2 phosphorylation of Bcl-xL after stress converts it to a pro-apoptotic protein mimicking Bax/Bak. Cell Death Discov. 2016;2: pubmed
- de Andrade G, Kunzelman L, Merrill M, Fuerst P. Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina. Mol Vis. 2014;20:1422-33 pubmed
- Kobayashi M, Hoshinaga Y, Miura N, Tokuda Y, Shigeoka S, Murai A, et al. Ascorbic acid deficiency decreases hepatic cytochrome P-450, especially CYP2B1/2B2, and simultaneously induces heme oxygenase-1 gene expression in scurvy-prone ODS rats. Biosci Biotechnol Biochem. 2014;78:1060-6 pubmed publisher
- Jin J, Whittaker R, Glassy M, Barlow S, Gottlieb R, Glembotski C. Localization of phosphorylated alphaB-crystallin to heart mitochondria during ischemia-reperfusion. Am J Physiol Heart Circ Physiol. 2008;294:H337-44 pubmed
- Oishi Y, Ogata T, Yamamoto K, Terada M, Ohira T, Ohira Y, et al. Cellular adaptations in soleus muscle during recovery after hindlimb unloading. Acta Physiol (Oxf). 2008;192:381-95 pubmed
- Campian J, Gao X, Qian M, Eaton J. Cytochrome C oxidase activity and oxygen tolerance. J Biol Chem. 2007;282:12430-8 pubmed
- Adhami F, Liao G, Morozov Y, Schloemer A, Schmithorst V, Lorenz J, et al. Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy. Am J Pathol. 2006;169:566-83 pubmed
- Endo H, Kamada H, Nito C, Nishi T, Chan P. Mitochondrial translocation of p53 mediates release of cytochrome c and hippocampal CA1 neuronal death after transient global cerebral ischemia in rats. J Neurosci. 2006;26:7974-83 pubmed
- Ming L, Wang P, Bank A, Yu J, Zhang L. PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells. J Biol Chem. 2006;281:16034-42 pubmed
- Sarkar S, Floto R, Berger Z, Imarisio S, Cordenier A, Pasco M, et al. Lithium induces autophagy by inhibiting inositol monophosphatase. J Cell Biol. 2005;170:1101-11 pubmed
- Wong H, Fricker M, Wyttenbach A, Villunger A, Michalak E, Strasser A, et al. Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite. Mol Cell Biol. 2005;25:8732-47 pubmed
- Bu L, Lephart E. Soy isoflavones modulate the expression of BAD and neuron-specific beta III tubulin in male rat brain. Neurosci Lett. 2005;385:153-7 pubmed
- Rodolfo C, Mormone E, Matarrese P, Ciccosanti F, Farrace M, Garofano E, et al. Tissue transglutaminase is a multifunctional BH3-only protein. J Biol Chem. 2004;279:54783-92 pubmed
- Cao J, Semenova M, Solovyan V, Han J, Coffey E, Courtney M. Distinct requirements for p38alpha and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death. J Biol Chem. 2004;279:35903-13 pubmed
- Kim T, Zhao Y, Ding W, Shin J, He X, Seo Y, et al. Bid-cardiolipin interaction at mitochondrial contact site contributes to mitochondrial cristae reorganization and cytochrome C release. Mol Biol Cell. 2004;15:3061-72 pubmed
- Watts J, Kline J, Thornton L, Grattan R, Brar S. Metabolic dysfunction and depletion of mitochondria in hearts of septic rats. J Mol Cell Cardiol. 2004;36:141-50 pubmed
- Berryman M, Goldenring J. CLIC4 is enriched at cell-cell junctions and colocalizes with AKAP350 at the centrosome and midbody of cultured mammalian cells. Cell Motil Cytoskeleton. 2003;56:159-72 pubmed
- Soane L, Cho H, Niculescu F, Rus H, Shin M. C5b-9 terminal complement complex protects oligodendrocytes from death by regulating Bad through phosphatidylinositol 3-kinase/Akt pathway. J Immunol. 2001;167:2305-11 pubmed
- Wagenknecht B, Hermisson M, Groscurth P, Liston P, Krammer P, Weller M. Proteasome inhibitor-induced apoptosis of glioma cells involves the processing of multiple caspases and cytochrome c release. J Neurochem. 2000;75:2288-97 pubmed
- Zhou H, Li X, Meinkoth J, Pittman R. Akt regulates cell survival and apoptosis at a postmitochondrial level. J Cell Biol. 2000;151:483-94 pubmed
- Liu H, Lo C, Jones B, Pradhan Z, Srinivasan A, Valentino K, et al. Inhibition of c-Myc expression sensitizes hepatocytes to tumor necrosis factor-induced apoptosis and necrosis. J Biol Chem. 2000;275:40155-62 pubmed
- Atlante A, Calissano P, Bobba A, Azzariti A, Marra E, Passarella S. Cytochrome c is released from mitochondria in a reactive oxygen species (ROS)-dependent fashion and can operate as a ROS scavenger and as a respiratory substrate in cerebellar neurons undergoing excitotoxic death. J Biol Chem. 2000;275:37159-66 pubmed
- Liu M, Spremulli L. Interaction of mammalian mitochondrial ribosomes with the inner membrane. J Biol Chem. 2000;275:29400-6 pubmed
- von Kleist Retzow J, Vial E, Chantrel Groussard K, Rotig A, Munnich A, Rustin P, et al. Biochemical, genetic and immunoblot analyses of 17 patients with an isolated cytochrome c oxidase deficiency. Biochim Biophys Acta. 1999;1455:35-44 pubmed
- Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, et al. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell. 1999;98:115-24 pubmed
- Tang D, Lahti J, Grenet J, Kidd V. Cycloheximide-induced T-cell death is mediated by a Fas-associated death domain-dependent mechanism. J Biol Chem. 1999;274:7245-52 pubmed
- Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell. 1998;94:481-90 pubmed
- Vander Heiden M, Chandel N, Williamson E, Schumacker P, Thompson C. Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell. 1997;91:627-37 pubmed
- Taanman J, Bodnar A, Cooper J, Morris A, Clayton P, Leonard J, et al. Molecular mechanisms in mitochondrial DNA depletion syndrome. Hum Mol Genet. 1997;6:935-42 pubmed
- Capaldi R, Marusich M, Taanman J. Mammalian cytochrome-c oxidase: characterization of enzyme and immunological detection of subunits in tissue extracts and whole cells. Methods Enzymol. 1995;260:117-32 pubmed
- Capaldi R, Halphen D, Zhang Y, Yanamura W. Complexity and tissue specificity of the mitochondrial respiratory chain. J Bioenerg Biomembr. 1988;20:291-311 pubmed
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