This is a Validated Antibody Database (VAD) review about thale cres.. NRPB1, based on 44 published articles (read how Labome selects the articles), using NRPB1 antibody in all methods. It is aimed to help Labome visitors find the most suited NRPB1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
NRPB1 synonym: F4B14.70; F4B14_70; RNA POLYMERASE II LARGE SUBUNIT; RNA polymerase II large subunit; RNA_POL_II_LS; RNA_POL_II_LSRNA_POL_II_LS; RPB1

Abcam
mouse monoclonal (4H8)
  • western blot; human; 1:1000; loading ...; fig 4f
Abcam NRPB1 antibody (Abcam, ab5408) was used in western blot on human samples at 1:1000 (fig 4f). Nat Commun (2022) ncbi
mouse monoclonal (4H8)
  • immunocytochemistry; mouse; fig s7c
Abcam NRPB1 antibody (Abcam, ab5408) was used in immunocytochemistry on mouse samples (fig s7c). Nature (2021) ncbi
mouse monoclonal (4H8)
  • western blot; human; loading ...; fig 2h
Abcam NRPB1 antibody (Abcam, 4H8) was used in western blot on human samples (fig 2h). Cell (2020) ncbi
mouse monoclonal (4H8)
  • immunocytochemistry; mouse; 1:2000; loading ...; fig s19b
Abcam NRPB1 antibody (Abcam, ab5408) was used in immunocytochemistry on mouse samples at 1:2000 (fig s19b). Life Sci Alliance (2020) ncbi
mouse monoclonal (4H8)
  • ChIP-Seq; human; ; loading ...; fig 2a
Abcam NRPB1 antibody (Abcam, ab5408) was used in ChIP-Seq on human samples at (fig 2a). elife (2019) ncbi
mouse monoclonal (4H8)
  • ChIP-Seq; human; loading ...; fig 4b, e7n
Abcam NRPB1 antibody (Abcam, ab5408) was used in ChIP-Seq on human samples (fig 4b, e7n). Nature (2019) ncbi
mouse monoclonal (4H8)
  • ChIP-Seq; mouse; loading ...; fig 5b
Abcam NRPB1 antibody (Abcam, ab5408) was used in ChIP-Seq on mouse samples (fig 5b). Nucleic Acids Res (2018) ncbi
mouse monoclonal (4H8)
  • immunoprecipitation; human; loading ...; fig 4h
Abcam NRPB1 antibody (Abcam, ab5408) was used in immunoprecipitation on human samples (fig 4h). Nucleic Acids Res (2017) ncbi
mouse monoclonal (4H8)
  • ChIP-Seq; mouse; loading ...; fig 1
In order to investigate the function of CTCF sites in the casein locus, Abcam NRPB1 antibody (Abcam, ab5408) was used in ChIP-Seq on mouse samples (fig 1). Nucleic Acids Res (2017) ncbi
mouse monoclonal (4H8)
  • western blot; mouse; fig 4e
Abcam NRPB1 antibody (Abcam, ab5408) was used in western blot on mouse samples (fig 4e). Sci Rep (2017) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; human; loading ...; fig 4i
Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on human samples (fig 4i). Sci Signal (2017) ncbi
mouse monoclonal (4H8)
  • immunocytochemistry; African green monkey; loading ...; fig 4
Abcam NRPB1 antibody (Abcam, 4H8) was used in immunocytochemistry on African green monkey samples (fig 4). PLoS Pathog (2017) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; human; loading ...; fig 2e
In order to determine the molecular mechanisms that enable JAK2/signal transducer and activator of transcription 5 to access promoters of genes implicated in breast cancer pathogenesis, Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on human samples (fig 2e). J Biol Chem (2017) ncbi
mouse monoclonal (4H8)
  • western blot; human; 1:500; loading ...; fig 5c
Abcam NRPB1 antibody (Abcam, Ab5408) was used in western blot on human samples at 1:500 (fig 5c). Oncogene (2017) ncbi
mouse monoclonal (4H8)
  • western blot; human; loading ...; fig 2e
In order to explore acetylation of arrest-defective protein 1 in prostate cancer cells, Abcam NRPB1 antibody (AbCam, 5408) was used in western blot on human samples (fig 2e). Oncotarget (2016) ncbi
mouse monoclonal (4H8)
In order to characterize male XX chromosomes that recombine and undergo pachytene chromatin inactivation as a form of unique sex chromosome systems in Ellobius, Abcam NRPB1 antibody (Abcam, 5408) was used . Sci Rep (2016) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; mouse; fig 5
Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on mouse samples (fig 5). PLoS Genet (2016) ncbi
mouse monoclonal (4H8)
  • western blot; mouse; fig 4
In order to assess the molecular reader and transcriptional co-regulator of H3k4me2/3 called PHF13, Abcam NRPB1 antibody (Abcam, ab5408) was used in western blot on mouse samples (fig 4). elife (2016) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; human; fig e9
Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on human samples (fig e9). Nature (2016) ncbi
mouse monoclonal (4H8)
  • ELISA; Austrofundulus limnaeus; 1:1000; loading ...; fig 6b
In order to analyze chromatin in vertebrate embryo diapause, Abcam NRPB1 antibody (Abcam, ab5408) was used in ELISA on Austrofundulus limnaeus samples at 1:1000 (fig 6b). J Exp Biol (2016) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; human; fig 3
Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on human samples (fig 3). Mol Cancer Ther (2016) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; human; fig 3
Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on human samples (fig 3). Sci Rep (2015) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; mouse; loading ...; fig 5c
Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on mouse samples (fig 5c). Mol Cell Biol (2016) ncbi
mouse monoclonal (4H8)
  • ChIP-Seq; mouse; fig 3
Abcam NRPB1 antibody (Abcam, ab5408) was used in ChIP-Seq on mouse samples (fig 3). Nucleic Acids Res (2016) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; human; fig 6
Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on human samples (fig 6). PLoS Pathog (2015) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; fruit fly ; fig s6
In order to assess the relationship between SU(VAR)3-9 and RRP6 targets RRP6 to heterochromatin and contributes to drosophila melanogaster heterochromatin maintenance, Abcam NRPB1 antibody (abcam, ab5408) was used in chromatin immunoprecipitation on fruit fly samples (fig s6). PLoS Genet (2015) ncbi
mouse monoclonal (4H8)
  • ChIP-Seq; mouse; fig s1
Abcam NRPB1 antibody (Abcam, ab5408) was used in ChIP-Seq on mouse samples (fig s1). Mol Cell Biol (2015) ncbi
mouse monoclonal (4H8)
  • ChIP-Seq; mouse; fig 5
Abcam NRPB1 antibody (abcam, ab5408) was used in ChIP-Seq on mouse samples (fig 5). Nucleic Acids Res (2015) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; human
In order to develop a novel, programmable transcription factor prototype, Abcam NRPB1 antibody (Abcam, 4H8) was used in chromatin immunoprecipitation on human samples . Nucleic Acids Res (2015) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; fission yeast
In order to study the role of Fft3 in chromatin organization, Abcam NRPB1 antibody (abcam, ab5408) was used in chromatin immunoprecipitation on fission yeast samples . PLoS Genet (2015) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; human; fig 6
Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on human samples (fig 6). Biochim Biophys Acta (2015) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; human; fig 5
Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on human samples (fig 5). Nucleic Acids Res (2015) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; human; fig 5
Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on human samples (fig 5). Nat Immunol (2015) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; mouse; loading ...; fig 3b
Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on mouse samples (fig 3b). BMC Dev Biol (2015) ncbi
mouse monoclonal (4H8)
  • ChIP-Seq; fission yeast; loading ...
Abcam NRPB1 antibody (Abcam, ab5408) was used in ChIP-Seq on fission yeast samples . elife (2014) ncbi
mouse monoclonal (4H8)
  • ChIP-Seq; mouse
  • chromatin immunoprecipitation; mouse
Abcam NRPB1 antibody (abcam, 4H8) was used in ChIP-Seq on mouse samples and in chromatin immunoprecipitation on mouse samples . Cell (2014) ncbi
mouse monoclonal (4H8)
  • western blot; human; fig 1b
In order to study the regulation of premature cleavage and polyadenylation by TRAP150, Abcam NRPB1 antibody (Abcam, 4H8) was used in western blot on human samples (fig 1b). Nucleic Acids Res (2014) ncbi
mouse monoclonal (4H8)
  • western blot; human
Abcam NRPB1 antibody (Abcam, ab5408) was used in western blot on human samples . Nature (2014) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; human
Abcam NRPB1 antibody (Abcam Company, ab5408) was used in chromatin immunoprecipitation on human samples . Mol Cells (2014) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; human
Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; human
  • western blot; human
Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on human samples and in western blot on human samples . Nucleic Acids Res (2014) ncbi
mouse monoclonal (4H8)
  • ChIP-Seq; human
Abcam NRPB1 antibody (Abcam, ab5408) was used in ChIP-Seq on human samples . Methods Mol Biol (2013) ncbi
mouse monoclonal (4H8)
  • chromatin immunoprecipitation; mouse
Abcam NRPB1 antibody (Abcam, ab5408) was used in chromatin immunoprecipitation on mouse samples . Oncogene (2012) ncbi
mouse monoclonal (4H8)
  • ChIP-Seq; mouse; fig s2
Abcam NRPB1 antibody (Abcam, ab5408) was used in ChIP-Seq on mouse samples (fig s2). BMC Dev Biol (2011) ncbi
Articles Reviewed
  1. Zhang Y, Fang Y, Tang Y, Han S, Jia J, Wan X, et al. SMYD5 catalyzes histone H3 lysine 36 trimethylation at promoters. Nat Commun. 2022;13:3190 pubmed publisher
  2. Takei Y, Yun J, Zheng S, Ollikainen N, Pierson N, White J, et al. Integrated spatial genomics reveals global architecture of single nuclei. Nature. 2021;590:344-350 pubmed publisher
  3. Tufegdzic Vidakovic A, Mitter R, Kelly G, Neumann M, Harreman M, Rodríguez Martínez M, et al. Regulation of the RNAPII Pool Is Integral to the DNA Damage Response. Cell. 2020;180:1245-1261.e21 pubmed publisher
  4. McNicoll F, Kühnel A, Biswas U, Hempel K, Whelan G, Eichele G, et al. Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2. Life Sci Alliance. 2020;3: pubmed publisher
  5. Dremel S, DeLuca N. Herpes simplex viral nucleoprotein creates a competitive transcriptional environment facilitating robust viral transcription and host shut off. elife. 2019;8: pubmed publisher
  6. Yoshimi A, Lin K, Wiseman D, Rahman M, Pastore A, Wang B, et al. Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis. Nature. 2019;574:273-277 pubmed publisher
  7. Lee H, Willi M, Shin H, Liu C, Hennighausen L. Progressing super-enhancer landscape during mammary differentiation controls tissue-specific gene regulation. Nucleic Acids Res. 2018;46:10796-10809 pubmed publisher
  8. Blank M, Chen S, Poetz F, Schnolzer M, Voit R, Grummt I. SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription. Nucleic Acids Res. 2017;45:2675-2686 pubmed publisher
  9. Lee H, Willi M, Wang C, Yang C, Smith H, Liu C, et al. Functional assessment of CTCF sites at cytokine-sensing mammary enhancers using CRISPR/Cas9 gene editing in mice. Nucleic Acids Res. 2017;45:4606-4618 pubmed publisher
  10. Raciti G, Spinelli R, Desiderio A, Longo M, Parrillo L, Nigro C, et al. Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity. Sci Rep. 2017;7:43526 pubmed publisher
  11. Viscarra J, Wang Y, Hong I, Sul H. Transcriptional activation of lipogenesis by insulin requires phosphorylation of MED17 by CK2. Sci Signal. 2017;10: pubmed publisher
  12. Dembowski J, Dremel S, DeLuca N. Replication-Coupled Recruitment of Viral and Cellular Factors to Herpes Simplex Virus Type 1 Replication Forks for the Maintenance and Expression of Viral Genomes. PLoS Pathog. 2017;13:e1006166 pubmed publisher
  13. Schauwecker S, Kim J, Licht J, Clevenger C. Histone H1 and Chromosomal Protein HMGN2 Regulate Prolactin-induced STAT5 Transcription Factor Recruitment and Function in Breast Cancer Cells. J Biol Chem. 2017;292:2237-2254 pubmed publisher
  14. Harrod A, Fulton J, Nguyen V, Periyasamy M, Ramos Garcia L, Lai C, et al. Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer. Oncogene. 2017;36:2286-2296 pubmed publisher
  15. Depaolo J, Wang Z, Guo J, Zhang G, Qian C, Zhang H, et al. Acetylation of androgen receptor by ARD1 promotes dissociation from HSP90 complex and prostate tumorigenesis. Oncotarget. 2016;7:71417-71428 pubmed publisher
  16. Matveevsky S, Bakloushinskaya I, Kolomiets O. Unique sex chromosome systems in Ellobius: How do male XX chromosomes recombine and undergo pachytene chromatin inactivation?. Sci Rep. 2016;6:29949 pubmed publisher
  17. Li R, Dong Q, Yuan X, Zeng X, Gao Y, Chiao C, et al. Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome. PLoS Genet. 2016;12:e1006129 pubmed publisher
  18. Chung H, Xu C, Fuchs A, Mund A, Lange M, Staege H, et al. PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3. elife. 2016;5: pubmed publisher
  19. Zhao D, Gish G, Braunschweig U, Li Y, Ni Z, Schmitges F, et al. SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Nature. 2016;529:48-53 pubmed publisher
  20. Toni L, Padilla P. Developmentally arrested Austrofundulus limnaeus embryos have changes in post-translational modifications of histone H3. J Exp Biol. 2016;219:544-52 pubmed publisher
  21. Hernando H, Gelato K, Lesche R, Beckmann G, Koehr S, Otto S, et al. EZH2 Inhibition Blocks Multiple Myeloma Cell Growth through Upregulation of Epithelial Tumor Suppressor Genes. Mol Cancer Ther. 2016;15:287-98 pubmed publisher
  22. Mannini L, C Lamaze F, Cucco F, Amato C, Quarantotti V, Rizzo I, et al. Mutant cohesin affects RNA polymerase II regulation in Cornelia de Lange syndrome. Sci Rep. 2015;5:16803 pubmed publisher
  23. Stees J, HOSSAIN M, Sunose T, Kudo Y, Pardo C, Nabilsi N, et al. High Fractional Occupancy of a Tandem Maf Recognition Element and Its Role in Long-Range β-Globin Gene Regulation. Mol Cell Biol. 2016;36:238-50 pubmed publisher
  24. Metser G, Shin H, Wang C, Yoo K, Oh S, Villarino A, et al. An autoregulatory enhancer controls mammary-specific STAT5 functions. Nucleic Acids Res. 2016;44:1052-63 pubmed publisher
  25. Nawandar D, Wang A, Makielski K, Lee D, Ma S, Barlow E, et al. Differentiation-Dependent KLF4 Expression Promotes Lytic Epstein-Barr Virus Infection in Epithelial Cells. PLoS Pathog. 2015;11:e1005195 pubmed publisher
  26. Eberle A, Jordán Pla A, Gañez Zapater A, Hessle V, Silberberg G, von Euler A, et al. An Interaction between RRP6 and SU(VAR)3-9 Targets RRP6 to Heterochromatin and Contributes to Heterochromatin Maintenance in Drosophila melanogaster. PLoS Genet. 2015;11:e1005523 pubmed publisher
  27. Onodera A, Tumes D, Watanabe Y, Hirahara K, Kaneda A, Sugiyama F, et al. Spatial Interplay between Polycomb and Trithorax Complexes Controls Transcriptional Activity in T Lymphocytes. Mol Cell Biol. 2015;35:3841-53 pubmed publisher
  28. Yoo K, Oh S, Kang K, Hensel T, Robinson G, Hennighausen L. Loss of EZH2 results in precocious mammary gland development and activation of STAT5-dependent genes. Nucleic Acids Res. 2015;43:8774-89 pubmed publisher
  29. Fimiani C, Goina E, Mallamaci A. Upregulating endogenous genes by an RNA-programmable artificial transactivator. Nucleic Acids Res. 2015;43:7850-64 pubmed publisher
  30. Steglich B, Strålfors A, Khorosjutina O, Persson J, Smialowska A, Javerzat J, et al. The Fun30 chromatin remodeler Fft3 controls nuclear organization and chromatin structure of insulators and subtelomeres in fission yeast. PLoS Genet. 2015;11:e1005101 pubmed publisher
  31. Hussain I, Bhan A, Ansari K, Deb P, Bobzean S, Perrotti L, et al. Bisphenol-A induces expression of HOXC6, an estrogen-regulated homeobox-containing gene associated with breast cancer. Biochim Biophys Acta. 2015;1849:697-708 pubmed publisher
  32. Ekumi K, Paculova H, Lenasi T, Pospichalova V, Bösken C, Rybarikova J, et al. Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex. Nucleic Acids Res. 2015;43:2575-89 pubmed publisher
  33. Ranzani V, Rossetti G, Panzeri I, Arrigoni A, Bonnal R, Curti S, et al. The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4. Nat Immunol. 2015;16:318-325 pubmed publisher
  34. Sun C, Denisenko O, Sheth B, Cox A, Lucas E, Smyth N, et al. Epigenetic regulation of histone modifications and Gata6 gene expression induced by maternal diet in mouse embryoid bodies in a model of developmental programming. BMC Dev Biol. 2015;15:3 pubmed publisher
  35. Lorenz D, Meyer L, Grady P, Meyer M, Cam H. Heterochromatin assembly and transcriptome repression by Set1 in coordination with a class II histone deacetylase. elife. 2014;3:e04506 pubmed publisher
  36. Qian J, Wang Q, Dose M, Pruett N, Kieffer Kwon K, Resch W, et al. B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity. Cell. 2014;159:1524-37 pubmed publisher
  37. Lee K, Tarn W. TRAP150 activates splicing in composite terminal exons. Nucleic Acids Res. 2014;42:12822-32 pubmed publisher
  38. Asangani I, Dommeti V, Wang X, Malik R, Cieslik M, Yang R, et al. Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer. Nature. 2014;510:278-82 pubmed publisher
  39. Li Y, Bai H, Zhang Z, Li W, Dong L, Wei X, et al. The up-regulation of miR-199b-5p in erythroid differentiation is associated with GATA-1 and NF-E2. Mol Cells. 2014;37:213-9 pubmed publisher
  40. Wakai M, Abe S, Kazuki Y, Oshimura M, Ishikawa F. A human artificial chromosome recapitulates the metabolism of native telomeres in mammalian cells. PLoS ONE. 2014;9:e88530 pubmed publisher
  41. Seo J, Kim K, Chang D, Kang H, Shin E, Kwon J, et al. Genome-wide reorganization of histone H2AX toward particular fragile sites on cell activation. Nucleic Acids Res. 2014;42:1016-25 pubmed publisher
  42. An C, Hagiwara N. Genome-wide analysis of transcription factor-binding sites in skeletal muscle cells using ChIP-seq. Methods Mol Biol. 2013;1067:51-64 pubmed publisher
  43. Zarnegar M, Rothenberg E. Ikaros represses and activates PU.1 cell-type-specifically through the multifunctional Sfpi1 URE and a myeloid specific enhancer. Oncogene. 2012;31:4647-54 pubmed publisher
  44. An C, Dong Y, Hagiwara N. Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6. BMC Dev Biol. 2011;11:59 pubmed publisher