This is a Validated Antibody Database (VAD) review about rat histone deacetylase 3, based on 23 published articles (read how Labome selects the articles), using histone deacetylase 3 antibody in all methods. It is aimed to help Labome visitors find the most suited histone deacetylase 3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Cell Signaling Technology
mouse monoclonal (7G6C5)
  • immunohistochemistry knockout validation; mouse; fig S1a
Cell Signaling Technology histone deacetylase 3 antibody (Cell Signaling, 3949) was used in immunohistochemistry knockout validation on mouse samples (fig S1a). Nat Neurosci (2016) ncbi
Abcam
mouse monoclonal (3G6)
  • western blot; mouse; loading ...; fig 2e
Abcam histone deacetylase 3 antibody (Abcam, ab187945) was used in western blot on mouse samples (fig 2e). Science (2019) ncbi
domestic rabbit monoclonal (Y415)
  • immunocytochemistry; human; loading ...; fig 3d
  • western blot; human; loading ...; fig 3c
Abcam histone deacetylase 3 antibody (Abcam, ab32369) was used in immunocytochemistry on human samples (fig 3d) and in western blot on human samples (fig 3c). Cell (2019) ncbi
domestic rabbit monoclonal (Y415)
  • western blot; zebrafish ; 1:1000; loading ...; fig 7p
In order to investigate the genetic regulators of endothelial precursors in great vessel vasculogenesis, Abcam histone deacetylase 3 antibody (Abcam, ab32369) was used in western blot on zebrafish samples at 1:1000 (fig 7p). Nat Commun (2017) ncbi
domestic rabbit monoclonal (Y415)
  • chromatin immunoprecipitation; human; fig 6
  • western blot; human; fig s1
Abcam histone deacetylase 3 antibody (Abcam, ab32369) was used in chromatin immunoprecipitation on human samples (fig 6) and in western blot on human samples (fig s1). Sci Rep (2016) ncbi
domestic rabbit monoclonal (Y415)
  • western blot; human; 1:1000; fig 6a
Abcam histone deacetylase 3 antibody (Abcam, ab32369) was used in western blot on human samples at 1:1000 (fig 6a). Oncotarget (2016) ncbi
domestic rabbit monoclonal (Y415)
  • immunohistochemistry; human; 1:200; fig 2
Abcam histone deacetylase 3 antibody (Abcam, ab32369) was used in immunohistochemistry on human samples at 1:200 (fig 2). Cancer Sci (2015) ncbi
domestic rabbit monoclonal (Y415)
  • western blot; mouse; 1:2000; fig 3
Abcam histone deacetylase 3 antibody (Abcam, Ab32369) was used in western blot on mouse samples at 1:2000 (fig 3). Proc Natl Acad Sci U S A (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-3)
Santa Cruz Biotechnology histone deacetylase 3 antibody (Santa Cruz, sc-376957) was used . Cell (2019) ncbi
mouse monoclonal (B-12)
  • western blot; human; fig 3
In order to analyze tamoxifen-resistance in ERalpha-positive breast cancer by degradation of NCoR due to COPS5 amplification and overexpression, Santa Cruz Biotechnology histone deacetylase 3 antibody (Santa Cruz, sc-17795) was used in western blot on human samples (fig 3). Nat Commun (2016) ncbi
mouse monoclonal (B-12)
  • western blot; mouse; fig 5
Santa Cruz Biotechnology histone deacetylase 3 antibody (Santa Cruz, sc-17795) was used in western blot on mouse samples (fig 5). elife (2016) ncbi
mouse monoclonal (40)
  • western blot; rat
Santa Cruz Biotechnology histone deacetylase 3 antibody (Santa Cruz Biotechnology, sc-136290) was used in western blot on rat samples . Cell Signal (2014) ncbi
mouse monoclonal (B-12)
  • western blot; human
Santa Cruz Biotechnology histone deacetylase 3 antibody (Santa Cruz, sc-17795) was used in western blot on human samples . Cancer Res (2013) ncbi
Cell Signaling Technology
mouse monoclonal (7G6C5)
  • western blot; human; loading ...; fig 3s2a
Cell Signaling Technology histone deacetylase 3 antibody (Cell Signaling, 3949) was used in western blot on human samples (fig 3s2a). elife (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s1
Cell Signaling Technology histone deacetylase 3 antibody (Cell Signaling Technology, 2632) was used in western blot on human samples (fig s1). Cell Rep (2018) ncbi
mouse monoclonal (7G6C5)
  • western blot; human; 1:1000; loading ...; fig s4a
Cell Signaling Technology histone deacetylase 3 antibody (Cell Signaling, 3949) was used in western blot on human samples at 1:1000 (fig s4a). Nature (2018) ncbi
mouse monoclonal (7G6C5)
  • western blot; human; loading ...; fig 6c
Cell Signaling Technology histone deacetylase 3 antibody (Cell signaling, 3949) was used in western blot on human samples (fig 6c). Ann Neurol (2016) ncbi
mouse monoclonal (7G6C5)
  • immunohistochemistry knockout validation; mouse; fig S1a
Cell Signaling Technology histone deacetylase 3 antibody (Cell Signaling, 3949) was used in immunohistochemistry knockout validation on mouse samples (fig S1a). Nat Neurosci (2016) ncbi
mouse monoclonal (7G6C5)
  • western blot; rat; fig 5c
Cell Signaling Technology histone deacetylase 3 antibody (Cell signaling, 3949) was used in western blot on rat samples (fig 5c). Cell Signal (2016) ncbi
mouse monoclonal (7G6C5)
  • western blot; human; fig 7
Cell Signaling Technology histone deacetylase 3 antibody (Cell signaling, 3949) was used in western blot on human samples (fig 7). Oncogenesis (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:100; fig 5
  • western blot; human; 1:500; fig 1b
Cell Signaling Technology histone deacetylase 3 antibody (Cell Signaling Technology, 2632) was used in immunocytochemistry on human samples at 1:100 (fig 5) and in western blot on human samples at 1:500 (fig 1b). PLoS Pathog (2016) ncbi
mouse monoclonal (7G6C5)
  • immunocytochemistry; mouse; 1:100; loading ...; fig 7a
  • western blot; mouse; 1:1000; loading ...; fig 1b
In order to study the effects of a HDAC 3-selective inhibitor, RGFP966, on NF-kB and histones, Cell Signaling Technology histone deacetylase 3 antibody (Cell Signaling, 3949) was used in immunocytochemistry on mouse samples at 1:100 (fig 7a) and in western blot on mouse samples at 1:1000 (fig 1b). Biochem Pharmacol (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1b
In order to study the effects of a HDAC 3-selective inhibitor, RGFP966, on NF-kB and histones, Cell Signaling Technology histone deacetylase 3 antibody (Cell Signaling, 2632) was used in western blot on mouse samples at 1:1000 (fig 1b). Biochem Pharmacol (2016) ncbi
mouse monoclonal (7G6C5)
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology histone deacetylase 3 antibody (Cell Signaling, 3949P) was used in western blot on human samples at 1:1000 (fig 4). Cancer Sci (2015) ncbi
mouse monoclonal (7G6C5)
  • western blot; mouse; 1:1000
Cell Signaling Technology histone deacetylase 3 antibody (Cell Signaling, 3949) was used in western blot on mouse samples at 1:1000. Am J Physiol Heart Circ Physiol (2013) ncbi
BD Biosciences
mouse monoclonal (40/HDAC3)
  • western blot; human
BD Biosciences histone deacetylase 3 antibody (BD Biosciences, 611125) was used in western blot on human samples . PLoS ONE (2014) ncbi
Articles Reviewed
  1. Kuang Z, Wang Y, Li Y, Ye C, Ruhn K, Behrendt C, et al. The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3. Science. 2019;365:1428-1434 pubmed publisher
  2. Shi K, Yin X, Cai M, Yan Y, Jia C, Ma P, et al. PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors. elife. 2019;8: pubmed publisher
  3. Dai J, Huang Y, He X, Zhao M, Wang X, Liu Z, et al. Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity. Cell. 2019;: pubmed publisher
  4. Żylicz J, Bousard A, Zumer K, Dossin F, Mohammad E, da Rocha S, et al. The Implication of Early Chromatin Changes in X Chromosome Inactivation. Cell. 2019;176:182-197.e23 pubmed publisher
  5. Bainor A, Saini S, Calderon A, Casado Polanco R, Giner Ramirez B, Moncada C, et al. The HDAC-Associated Sin3B Protein Represses DREAM Complex Targets and Cooperates with APC/C to Promote Quiescence. Cell Rep. 2018;25:2797-2807.e8 pubmed publisher
  6. Zhu Y, Wang G, Cingoz O, Goff S. NP220 mediates silencing of unintegrated retroviral DNA. Nature. 2018;564:278-282 pubmed publisher
  7. Meng Z, Liu W, Xia Y, Yin H, Zhang C, Su D, et al. The pro-inflammatory signalling regulator Stat4 promotes vasculogenesis of great vessels derived from endothelial precursors. Nat Commun. 2017;8:14640 pubmed publisher
  8. Hu B, Arpag S, Zuchner S, Li J. A novel missense mutation of CMT2P alters transcription machinery. Ann Neurol. 2016;80:834-845 pubmed publisher
  9. Romani B, Kamali Jamil R, Hamidi Fard M, Rahimi P, Momen S, Aghasadeghi M, et al. HIV-1 Vpr reactivates latent HIV-1 provirus by inducing depletion of class I HDACs on chromatin. Sci Rep. 2016;6:31924 pubmed publisher
  10. Nott A, Cheng J, Gao F, Lin Y, Gjoneska E, Ko T, et al. Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior. Nat Neurosci. 2016;19:1497-1505 pubmed publisher
  11. Lu R, Hu X, Zhou J, Sun J, Zhu A, Xu X, et al. COPS5 amplification and overexpression confers tamoxifen-resistance in ER?-positive breast cancer by degradation of NCoR. Nat Commun. 2016;7:12044 pubmed publisher
  12. Rando G, Tan C, Khaled N, Montagner A, Leuenberger N, Bertrand Michel J, et al. Glucocorticoid receptor-PPAR? axis in fetal mouse liver prepares neonates for milk lipid catabolism. elife. 2016;5: pubmed publisher
  13. Lin Y, Warren C, Li J, McKinsey T, Russell B. Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ. Cell Signal. 2016;28:1015-24 pubmed publisher
  14. Chaudhary S, Madhukrishna B, Adhya A, Keshari S, Mishra S. Overexpression of caspase 7 is ER? dependent to affect proliferation and cell growth in breast cancer cells by targeting p21(Cip). Oncogenesis. 2016;5:e219 pubmed publisher
  15. Dreer M, Fertey J, van de Poel S, Straub E, Madlung J, Macek B, et al. Interaction of NCOR/SMRT Repressor Complexes with Papillomavirus E8^E2C Proteins Inhibits Viral Replication. PLoS Pathog. 2016;12:e1005556 pubmed publisher
  16. Leus N, van der Wouden P, van den Bosch T, Hooghiemstra W, Ourailidou M, Kistemaker L, et al. HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity. Biochem Pharmacol. 2016;108:58-74 pubmed publisher
  17. Huang R, Langdon S, Tse M, Mullen P, Um I, Faratian D, et al. The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer. Oncotarget. 2016;7:4695-711 pubmed publisher
  18. Liu X, Wang J, Li S, Li L, Huang M, Zhang Y, et al. Histone deacetylase 3 expression correlates with vasculogenic mimicry through the phosphoinositide3-kinase / ERK-MMP-laminin5γ2 signaling pathway. Cancer Sci. 2015;106:857-66 pubmed publisher
  19. Joliot V, Ait Mohamed O, Battisti V, Pontis J, Philipot O, Robin P, et al. The SWI/SNF subunit/tumor suppressor BAF47/INI1 is essential in cell cycle arrest upon skeletal muscle terminal differentiation. PLoS ONE. 2014;9:e108858 pubmed publisher
  20. Blakeslee W, Wysoczynski C, Fritz K, Nyborg J, Churchill M, McKinsey T. Class I HDAC inhibition stimulates cardiac protein SUMOylation through a post-translational mechanism. Cell Signal. 2014;26:2912-20 pubmed publisher
  21. Jamaladdin S, Kelly R, O Regan L, Dovey O, Hodson G, Millard C, et al. Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells. Proc Natl Acad Sci U S A. 2014;111:9840-5 pubmed publisher
  22. Medford H, Porter K, Marsh S. Immediate effects of a single exercise bout on protein O-GlcNAcylation and chromatin regulation of cardiac hypertrophy. Am J Physiol Heart Circ Physiol. 2013;305:H114-23 pubmed publisher
  23. Isaacs J, Antony L, Dalrymple S, Brennen W, Gerber S, Hammers H, et al. Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment. Cancer Res. 2013;73:1386-99 pubmed publisher