This is a Validated Antibody Database (VAD) review about rat bestrophin, based on 3 published articles (read how Labome selects the articles), using bestrophin antibody in all methods. It is aimed to help Labome visitors find the most suited bestrophin antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
bestrophin synonym: Vmd2; bestrophin-1; vitelliform macular dystrophy (Best disease, bestrophin); vitelliform macular dystrophy 2 homolog

Abcam
rabbit polyclonal
  • immunohistochemistry; human; 1:100; fig 5A
In order to establish an application to generate retinal pigmented epithelium from induced pluripotent stem cells, Abcam bestrophin antibody (Abcam, ab14927) was used in immunohistochemistry on human samples at 1:100 (fig 5A). PLoS ONE (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; tbl 1
  • immunohistochemistry - paraffin section; human; 1:200; tbl 1
Abcam bestrophin antibody (Abcam, ab14927) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (tbl 1) and in immunohistochemistry - paraffin section on human samples at 1:200 (tbl 1). Sci Rep (2016) ncbi
Novus Biologicals
mouse monoclonal (E6-6)
  • immunohistochemistry; human; 1:200; fig 4
In order to establish an application to generate retinal pigmented epithelium from induced pluripotent stem cells, Novus Biologicals bestrophin antibody (Novus, NB300-164) was used in immunohistochemistry on human samples at 1:200 (fig 4). PLoS ONE (2017) ncbi
mouse monoclonal (E6-6)
  • immunocytochemistry; dog; 1:500; loading ...; fig 1b
  • western blot; dog; 1:4000; loading ...; fig 1a
In order to characterize autosomal recessive bestrophinopathy mutations, Novus Biologicals bestrophin antibody (Novus Biologicals, NB300-164) was used in immunocytochemistry on dog samples at 1:500 (fig 1b) and in western blot on dog samples at 1:4000 (fig 1a). Dis Model Mech (2016) ncbi
Articles Reviewed
  1. Geng Z, Walsh P, Truong V, Hill C, Ebeling M, Kapphahn R, et al. Generation of retinal pigmented epithelium from iPSCs derived from the conjunctiva of donors with and without age related macular degeneration. PLoS ONE. 2017;12:e0173575 pubmed publisher
  2. Uggenti C, Briant K, Streit A, Thomson S, Koay Y, Baines R, et al. Restoration of mutant bestrophin-1 expression, localisation and function in a polarised epithelial cell model. Dis Model Mech. 2016;9:1317-1328 pubmed
  3. Brennan S, Wilkinson W, Tseng H, Finney B, Monk B, Dibble H, et al. The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR. Sci Rep. 2016;6:21975 pubmed publisher