This is a Validated Antibody Database (VAD) review about rat Zap70, based on 52 published articles (read how Labome selects the articles), using Zap70 antibody in all methods. It is aimed to help Labome visitors find the most suited Zap70 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Zap70 synonym: Srk

Invitrogen
mouse monoclonal (1E7.2)
  • flow cytometry; human; fig 2
In order to discuss using flow cytometry to assess Zap-70 in chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples (fig 2). Hematology (2012) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; mouse
In order to discuss how to study activation-dependent phosphorylation of proteins using mathematical modeling, Invitrogen Zap70 antibody (Invitrogen, 1E.7.2) was used in flow cytometry on mouse samples . PLoS ONE (2011) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human; fig 2
In order to discuss variance in the detection of ZAP-70 expression by clinical laboratories, Invitrogen Zap70 antibody (Invitrogen, 1E7.2) was used in flow cytometry on human samples (fig 2). Cytometry B Clin Cytom (2011) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human; tbl 4
In order to identify prognostic factors for chronic lymphocytic leukemia using a retrospective series, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples (tbl 4). Leuk Lymphoma (2011) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human; fig 2
In order to assess immature laminin receptor expression on patients with B cell malignancies, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples (fig 2). Leuk Res (2011) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human; fig 2
In order to examine expression of ZAP-70 throughout the disease course of chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples (fig 2). Eur J Haematol (2010) ncbi
mouse monoclonal (1E7.2)
  • immunocytochemistry; human
In order to investigate the contribution of ZAP-70 to chronic lymphocytic leukemia aggressiveness, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in immunocytochemistry on human samples . Leukemia (2010) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human
In order to test if the humoral immunity specific for the chronic lymphocytic leukemia-associated Ag oncofetal Ag/immature laminin receptor has a prognostic value in chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag Laboratories, 1E7.2) was used in flow cytometry on human samples . J Immunol (2008) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; mouse; fig 2
In order to assess the prognostic potential of Fc receptor-like molecules for chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Invitrogen, 1E7.2) was used in flow cytometry on mouse samples (fig 2). Blood (2008) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human
In order to determine ZAP-70 expression in patients with B-cell chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples . Haematologica (2008) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human; fig 5
In order to investigate chronic lymphocytic leukemia patient-derived samples' responses to MDM2 inhibitors and correlate responses with clinically important biomarkers, Invitrogen Zap70 antibody (Invitrogen, 1E7.2) was used in flow cytometry on human samples (fig 5). Blood (2008) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human
In order to develop an optimized cell staining procedure for detection of zeta-chain associated protein-70 via flow cytometry, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples . Cytometry B Clin Cytom (2008) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human; 200 ug/ml; fig 2
In order to describe an improved fluorescence-activate cell sorting lysing solution to measure ZAP-70 expression in B-cell chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag Laboratories, 1E7.2) was used in flow cytometry on human samples at 200 ug/ml (fig 2). Cytometry B Clin Cytom (2008) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human
In order to discuss prognostic factors ZAP-70, vascular endothelial growth factor and basic fibroblast growth factor and angiogenesis in chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag Laboratories, 1E7.2) was used in flow cytometry on human samples . Leuk Res (2007) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human; tbl 2
In order to study the cytogenetic, immunophenotypic, and VH gene usage characteristics of a family with B-cell chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples (tbl 2). Am J Clin Pathol (2007) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human; fig 3
In order to discuss the use of ZAP-70 expression to identify patients with poor prognosis of chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples (fig 3). Leukemia (2007) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human
In order to report a simple, fast, and reproducible flow cytometry method to detect ZAP-70 expression, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples . Cytometry B Clin Cytom (2007) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human
In order to review factors that influences the detection of ZAP-70 by flow cytometry, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples . Cytometry B Clin Cytom (2006) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human
In order to discuss the prognostic relevance and predictive power of ZAP-70 expression for patients with chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples . Cytometry B Clin Cytom (2006) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human
In order to discuss the clinical utility of assessing ZAP-70 and CD38 in chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples . Cytometry B Clin Cytom (2006) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human
In order to review the use of ZAP-70 expression as a biomarker in patients with chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples . Cytometry B Clin Cytom (2006) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human
In order to compare bone marrow samples with peripheral blood for ZAP-70 expression in patients with chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples . Cytometry B Clin Cytom (2006) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human
In order to investigate novel monoclonal antibodies to ZAP-70 to detect B-cell chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag Laboratories, 1E7.2) was used in flow cytometry on human samples . Cytometry B Clin Cytom (2006) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human
In order to discuss the use of ZAP-70 in chronic lymphocytic leukemia as a biomarker for patient management, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples . Cytometry B Clin Cytom (2006) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human
In order to discuss the use of ZAP-70 expression to examine chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples . Cytometry B Clin Cytom (2006) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human; fig 1
In order to use flow cytometry to assess the use of ZAP-70 expression as marker for B chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples (fig 1). Ann Hematol (2006) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human; tbl 1
In order to discuss the features of patients with chronic lymphocytic leukemia and infections, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples (tbl 1). Cancer (2006) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human; fig 1
In order to investigate ZAP-70 expression in B-cell malignancies, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples (fig 1). Leukemia (2006) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; mouse; tbl 1
In order to investigate IL-21 signaling in normal and chronic lymphocytic leukemia B cells, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on mouse samples (tbl 1). Blood (2006) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human
In order to examine Zap-70 expression in patients with chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples . Cytometry B Clin Cytom (2006) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human; tbl 1
In order to describe an immunophenotypic scoring system for B-cell chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag, IE7.2) was used in flow cytometry on human samples (tbl 1). J Cell Physiol (2006) ncbi
mouse monoclonal (1E7.2)
  • flow cytometry; human; fig 1
In order to measure ZAP-70 in cases of chronic lymphocytic leukemia, Invitrogen Zap70 antibody (Caltag, 1E7.2) was used in flow cytometry on human samples (fig 1). Clin Lab Haematol (2005) ncbi
Santa Cruz Biotechnology
mouse monoclonal (1E7.2)
  • western blot; mouse; 1:1000; loading ...; fig 6b
Santa Cruz Biotechnology Zap70 antibody (Santa Cruz, 32760) was used in western blot on mouse samples at 1:1000 (fig 6b). PLoS Biol (2021) ncbi
mouse monoclonal (1E7.2)
  • immunoprecipitation; human; fig 8
  • western blot; human; fig 8
  • immunoprecipitation; mouse; fig 6
  • western blot; mouse; fig 5
Santa Cruz Biotechnology Zap70 antibody (Santa Cruz, 1E7.2) was used in immunoprecipitation on human samples (fig 8), in western blot on human samples (fig 8), in immunoprecipitation on mouse samples (fig 6) and in western blot on mouse samples (fig 5). J Exp Med (2016) ncbi
mouse monoclonal (1E7.2)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology Zap70 antibody (SCBT, 1E7.2) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (1E7.2)
  • western blot; mouse; fig 6a
Santa Cruz Biotechnology Zap70 antibody (Santa Cruz Biotechnology, 1E7.2) was used in western blot on mouse samples (fig 6a). J Exp Med (2015) ncbi
mouse monoclonal (4H386)
  • western blot; human
Santa Cruz Biotechnology Zap70 antibody (Santa Cruz Biotechnology, 4H386) was used in western blot on human samples . Mol Cell Biol (2014) ncbi
mouse monoclonal (1E7.2)
  • western blot; human
Santa Cruz Biotechnology Zap70 antibody (Santa Cruz Biotechnologies, 1E7.2) was used in western blot on human samples . FEBS J (2014) ncbi
Abcam
domestic rabbit monoclonal
  • western blot; mouse; loading ...; fig 4d
Abcam Zap70 antibody (Abcam, ab32410) was used in western blot on mouse samples (fig 4d). Front Immunol (2018) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3a
Cell Signaling Technology Zap70 antibody (Cell signaling technology, 2704) was used in western blot on mouse samples (fig 3a). Cell Rep (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 6f
Cell Signaling Technology Zap70 antibody (Cell Signaling, 2704S) was used in western blot on human samples (fig 6f). Cell Rep (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 9a
In order to target Src family kinase Src-homology 2 domains with high selectivity via the development of synthetic binding proteins, termed monobodies, Cell Signaling Technology Zap70 antibody (Cell Signaling, 2704) was used in western blot on human samples (fig 9a). J Mol Biol (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s7b
In order to demonstrate that PD-1 inhibits T cell function primarily by inactivating CD28 signaling, Cell Signaling Technology Zap70 antibody (Cell Signaling, 2704) was used in western blot on human samples (fig s7b). Science (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 3d
In order to identify and characterize human ZAP-70 mutations associated with autoimmune disease, Cell Signaling Technology Zap70 antibody (Cell Signaling Technology, 2704S) was used in western blot on human samples (fig 3d). J Exp Med (2016) ncbi
BD Biosciences
mouse monoclonal (17A/P-ZAP70)
  • flow cytometry; mouse; loading ...; fig 3f
BD Biosciences Zap70 antibody (BD Biosciences, 557881) was used in flow cytometry on mouse samples (fig 3f). J Immunol (2022) ncbi
mouse monoclonal (17A/P-ZAP70)
  • flow cytometry; mouse; 1:10; fig 2k
BD Biosciences Zap70 antibody (BD Biosciences, 557881) was used in flow cytometry on mouse samples at 1:10 (fig 2k). Nat Immunol (2019) ncbi
mouse monoclonal (17A/P-ZAP70)
  • flow cytometry; mouse; loading ...; fig 6e
BD Biosciences Zap70 antibody (BD Biosciences, 557817) was used in flow cytometry on mouse samples (fig 6e). Cell Rep (2018) ncbi
mouse monoclonal (17A/P-ZAP70)
  • flow cytometry; mouse; loading ...; fig 3e
BD Biosciences Zap70 antibody (BD, 17A/P-ZAP70) was used in flow cytometry on mouse samples (fig 3e). J Exp Med (2017) ncbi
mouse monoclonal (17A/P-ZAP70)
  • flow cytometry; human; loading ...; fig 4b
In order to suggest that high Trx1 levels in patients with rheumatoid arthritis is responsible for the diminished binding of Tregalizumab to CD4-positive T cells, BD Biosciences Zap70 antibody (BD, 557881) was used in flow cytometry on human samples (fig 4b). Clin Transl Immunology (2016) ncbi
mouse monoclonal (29/ZAP70 Kinase)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences Zap70 antibody (BD, 29) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (29/ZAP70 Kinase)
  • western blot; human; fig 4
In order to study how conformational changes control T cell receptor association and activity of Zap70, BD Biosciences Zap70 antibody (BD Biosciences, 610240) was used in western blot on human samples (fig 4). Nat Immunol (2015) ncbi
mouse monoclonal (29/ZAP70 Kinase)
  • western blot; mouse; fig 2
BD Biosciences Zap70 antibody (BD, 610239) was used in western blot on mouse samples (fig 2). PLoS ONE (2015) ncbi
mouse monoclonal (17A/P-ZAP70)
  • flow cytometry; human
In order to investigate novel monoclonal antibodies to ZAP-70 to detect B-cell chronic lymphocytic leukemia, BD Biosciences Zap70 antibody (BD Biosciences, 17A/P-ZAP70) was used in flow cytometry on human samples . Cytometry B Clin Cytom (2006) ncbi
mouse monoclonal (29/ZAP70 Kinase)
  • immunoprecipitation; human
BD Biosciences Zap70 antibody (Transduction Laboratories, 29) was used in immunoprecipitation on human samples . Blood (2002) ncbi
Articles Reviewed
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  2. Sripada A, Sirohi K, Michalec L, Guo L, McKay J, Yadav S, et al. Sprouty2 positively regulates T cell function and airway inflammation through regulation of CSK and LCK kinases. PLoS Biol. 2021;19:e3001063 pubmed publisher
  3. Verma V, Shrimali R, Ahmad S, Dai W, Wang H, Lu S, et al. PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance. Nat Immunol. 2019;20:1231-1243 pubmed publisher
  4. Celis Gutierrez J, Blattmann P, Zhai Y, Jarmuzynski N, Ruminski K, Gregoire C, et al. Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy. Cell Rep. 2019;27:3315-3330.e7 pubmed publisher
  5. Obino D, Fetler L, Soza A, Malbec O, Saez J, Labarca M, et al. Galectin-8 Favors the Presentation of Surface-Tethered Antigens by Stabilizing the B Cell Immune Synapse. Cell Rep. 2018;25:3110-3122.e6 pubmed publisher
  6. Zhao Y, Harrison D, Song Y, Ji J, Huang J, Hui E. Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells. Cell Rep. 2018;24:379-390.e6 pubmed publisher
  7. Liang W, Mao S, Sun S, Li M, Li Z, Yu R, et al. Core Fucosylation of the T Cell Receptor Is Required for T Cell Activation. Front Immunol. 2018;9:78 pubmed publisher
  8. Kükenshöner T, Schmit N, Bouda E, Sha F, Pojer F, Koide A, et al. Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies. J Mol Biol. 2017;429:1364-1380 pubmed publisher
  9. Getahun A, Wemlinger S, Rudra P, Santiago M, van Dyk L, Cambier J. Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway. J Exp Med. 2017;214:931-941 pubmed publisher
  10. Hui E, Cheung J, Zhu J, Su X, Taylor M, Wallweber H, et al. T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition. Science. 2017;355:1428-1433 pubmed publisher
  11. Heim K, Dälken B, Faust S, Rharbaoui F, Engling A, Wallmeier H, et al. High thioredoxin-1 levels in rheumatoid arthritis patients diminish binding and signalling of the monoclonal antibody Tregalizumab. Clin Transl Immunology. 2016;5:e121 pubmed publisher
  12. Hu H, Wang H, Xiao Y, Jin J, Chang J, Zou Q, et al. Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination. J Exp Med. 2016;213:399-414 pubmed publisher
  13. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  14. Chan A, Punwani D, Kadlecek T, Cowan M, Olson J, Mathes E, et al. A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70. J Exp Med. 2016;213:155-65 pubmed publisher
  15. Klammt C, Novotná L, Li D, Wolf M, Blount A, Zhang K, et al. T cell receptor dwell times control the kinase activity of Zap70. Nat Immunol. 2015;16:961-9 pubmed publisher
  16. Zou Q, Jin J, Xiao Y, Hu H, Zhou X, Jie Z, et al. T cell development involves TRAF3IP3-mediated ERK signaling in the Golgi. J Exp Med. 2015;212:1323-36 pubmed publisher
  17. Silva O, Crocetti J, Humphries L, Burkhardt J, Miceli M. Discs Large Homolog 1 Splice Variants Regulate p38-Dependent and -Independent Effector Functions in CD8+ T Cells. PLoS ONE. 2015;10:e0133353 pubmed publisher
  18. Kloog Y, Mor A. Cytotoxic-T-lymphocyte antigen 4 receptor signaling for lymphocyte adhesion is mediated by C3G and Rap1. Mol Cell Biol. 2014;34:978-88 pubmed publisher
  19. Luis B, Carpino N. Insights into the suppressor of T-cell receptor (TCR) signaling-1 (Sts-1)-mediated regulation of TCR signaling through the use of novel substrate-trapping Sts-1 phosphatase variants. FEBS J. 2014;281:696-707 pubmed publisher
  20. Vroblova V, Smolej L, Krejsek J. Pitfalls and limitations of ZAP-70 detection in chronic lymphocytic leukemia. Hematology. 2012;17:268-74 pubmed publisher
  21. Deswal S, Schulze A, Hofer T, Schamel W. Quantitative analysis of protein phosphorylations and interactions by multi-colour IP-FCM as an input for kinetic modelling of signalling networks. PLoS ONE. 2011;6:e22928 pubmed publisher
  22. Degheidy H, Venzon D, Farooqui M, Abbasi F, Arthur D, Wilson W, et al. Methodological comparison of two anti-ZAP-70 antibodies. Cytometry B Clin Cytom. 2011;80:300-8 pubmed publisher
  23. Oliveira A, de la Banda E, Domingo Domenech E, Encuentra M, Mercadal S, Domingo A, et al. Prospective study of clinical and biological prognostic factors at diagnosis in patients with early stage B-cell chronic lymphocytic leukemia. Leuk Lymphoma. 2011;52:429-35 pubmed publisher
  24. Friedrichs B, Siegel S, Reimer R, Barsoum A, Coggin J, Kabelitz D, et al. High expression of the immature laminin receptor protein correlates with mutated IGVH status and predicts a favorable prognosis in chronic lymphocytic leukemia. Leuk Res. 2011;35:721-9 pubmed publisher
  25. Vroblova V, Vrbacky F, Hrudkova M, Jankovicova K, Schmitzova D, Maly J, et al. Significant change in ZAP-70 expression during the course of chronic lymphocytic leukemia. Eur J Haematol. 2010;84:513-7 pubmed publisher
  26. Zum Büschenfelde C, Wagner M, Lutzny G, Oelsner M, Feuerstacke Y, Decker T, et al. Recruitment of PKC-betaII to lipid rafts mediates apoptosis-resistance in chronic lymphocytic leukemia expressing ZAP-70. Leukemia. 2010;24:141-52 pubmed publisher
  27. Friedrichs B, Siegel S, Kloess M, Barsoum A, Coggin J, Rohrer J, et al. Humoral immune responses against the immature laminin receptor protein show prognostic significance in patients with chronic lymphocytic leukemia. J Immunol. 2008;180:6374-84 pubmed
  28. Li F, Ding S, Pan J, Shakhmatov M, Kashentseva E, Wu J, et al. FCRL2 expression predicts IGHV mutation status and clinical progression in chronic lymphocytic leukemia. Blood. 2008;112:179-87 pubmed publisher
  29. Gachard N, Salviat A, Boutet C, Arnoulet C, Durrieu F, Lenormand B, et al. Multicenter study of ZAP-70 expression in patients with B-cell chronic lymphocytic leukemia using an optimized flow cytometry method. Haematologica. 2008;93:215-23 pubmed publisher
  30. Saddler C, Ouillette P, Kujawski L, Shangary S, Talpaz M, Kaminski M, et al. Comprehensive biomarker and genomic analysis identifies p53 status as the major determinant of response to MDM2 inhibitors in chronic lymphocytic leukemia. Blood. 2008;111:1584-93 pubmed
  31. Preobrazhensky S, Bahler D. Optimization of flow cytometric measurement of ZAP-70 in chronic lymphocytic leukemia. Cytometry B Clin Cytom. 2008;74:118-27 pubmed
  32. Bekkema R, Tadema A, Daenen S, Kluin Nelemans H, Mulder A. An improved flow cytometric method using FACS Lysing Solution for measurement of ZAP-70 expression in B-cell chronic lymphocytic leukemia. Cytometry B Clin Cytom. 2008;74:40-4 pubmed
  33. Smolej L, Andrys C, Vroblova V. Modern prognostic factors and angiogenesis in chronic lymphocytic leukemia: more data needed. Leuk Res. 2007;31:1763-4 pubmed
  34. Aoun P, Zhou G, Chan W, Page C, Neth K, Pickering D, et al. Familial B-cell chronic lymphocytic leukemia: analysis of cytogenetic abnormalities, immunophenotypic profiles, and immunoglobulin heavy chain gene usage. Am J Clin Pathol. 2007;127:31-8 pubmed
  35. Zanotti R, Ambrosetti A, Lestani M, Ghia P, Pattaro C, Remo A, et al. ZAP-70 expression, as detected by immunohistochemistry on bone marrow biopsies from early-phase CLL patients, is a strong adverse prognostic factor. Leukemia. 2007;21:102-9 pubmed
  36. Le Garff Tavernier M, Ticchioni M, Brissard M, Salmon C, Raynaud S, Davi F, et al. National standardization of ZAP-70 determination by flow cytometry: the French experience. Cytometry B Clin Cytom. 2007;72:103-8 pubmed
  37. Letestu R, Rawstron A, Ghia P, Villamor N, Boeckx N, Leuven N, et al. Evaluation of ZAP-70 expression by flow cytometry in chronic lymphocytic leukemia: A multicentric international harmonization process. Cytometry B Clin Cytom. 2006;70:309-14 pubmed
  38. Zucchetto A, Bomben R, Bo M, Nanni P, Bulian P, Rossi F, et al. ZAP-70 expression in B-cell chronic lymphocytic leukemia: evaluation by external (isotypic) or internal (T/NK cells) controls and correlation with IgV(H) mutations. Cytometry B Clin Cytom. 2006;70:284-92 pubmed
  39. Rassenti L, Kipps T. Clinical utility of assessing ZAP-70 and CD38 in chronic lymphocytic leukemia. Cytometry B Clin Cytom. 2006;70:209-13 pubmed
  40. Shankey T, Forman M, Scibelli P, Cobb J, Smith C, Mills R, et al. An optimized whole blood method for flow cytometric measurement of ZAP-70 protein expression in chronic lymphocytic leukemia. Cytometry B Clin Cytom. 2006;70:259-69 pubmed
  41. Sheridan R, Mounajjed T, Ehrmann D, Hurtubise P, Schrager J. Comparison of bone marrow and peripheral blood ZAP-70 status examined by flow cytometric immunophenotyping in patients with chronic lymphocytic leukemia. Cytometry B Clin Cytom. 2006;70:320-1 pubmed
  42. Bojarska Junak A, Giannopoulos K, Kowal M, Dmoszynska A, Rolinski J. Comparison of methods for determining zeta-chain associated protein - 70 (ZAP-70) expression in patients with B-cell chronic lymphocytic leukemia (B-CLL). Cytometry B Clin Cytom. 2006;70:293-301 pubmed
  43. Marti G, Orfao A, Goolsby C. ZAP-70 in CLL: towards standardization of a biomarker for patient management: history of clinical cytometry special issue. Cytometry B Clin Cytom. 2006;70:197-200 pubmed
  44. Best O, Ibbotson R, Parker A, Davis Z, Orchard J, Oscier D. ZAP-70 by flow cytometry: a comparison of different antibodies, anticoagulants, and methods of analysis. Cytometry B Clin Cytom. 2006;70:235-41 pubmed
  45. Passam F, Tachynopoulou V, Skoumi D, Tsompanakou A, Stavropoulos Giokas A, Vadikolia C, et al. Feasibility of an easily applicable method of ZAP-70 measurement in chronic lymphocytic leukemia in the routine flow cytometry setting: A methodological approach. Ann Hematol. 2006;85:795-805 pubmed
  46. Francis S, Karanth M, Pratt G, Starczynski J, Hooper L, Fegan C, et al. The effect of immunoglobulin VH gene mutation status and other prognostic factors on the incidence of major infections in patients with chronic lymphocytic leukemia. Cancer. 2006;107:1023-33 pubmed
  47. Scielzo C, Camporeale A, Geuna M, Alessio M, Poggi A, Zocchi M, et al. ZAP-70 is expressed by normal and malignant human B-cell subsets of different maturational stage. Leukemia. 2006;20:689-95 pubmed
  48. de Totero D, Meazza R, Zupo S, Cutrona G, Matis S, Colombo M, et al. Interleukin-21 receptor (IL-21R) is up-regulated by CD40 triggering and mediates proapoptotic signals in chronic lymphocytic leukemia B cells. Blood. 2006;107:3708-15 pubmed
  49. Bakke A, Purtzer Z, Leis J, Huang J. A robust ratio metric method for analysis of Zap-70 expression in chronic lymphocytic leukemia (CLL). Cytometry B Clin Cytom. 2006;70:227-34 pubmed
  50. Zucchetto A, Bomben R, Dal Bo M, Sonego P, Nanni P, Rupolo M, et al. A scoring system based on the expression of six surface molecules allows the identification of three prognostic risk groups in B-cell chronic lymphocytic leukemia. J Cell Physiol. 2006;207:354-63 pubmed
  51. Gibbs G, Bromidge T, Howe D, Hopkins J, Johnson S. Comparison of flow cytometric methods for the measurement of ZAP-70 expression in a routine diagnostic laboratory. Clin Lab Haematol. 2005;27:258-66 pubmed
  52. Chen L, Widhopf G, Huynh L, Rassenti L, Rai K, Weiss A, et al. Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia. Blood. 2002;100:4609-14 pubmed