This is a Validated Antibody Database (VAD) review about rat Wwtr1, based on 19 published articles (read how Labome selects the articles), using Wwtr1 antibody in all methods. It is aimed to help Labome visitors find the most suited Wwtr1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Wwtr1 synonym: WW domain-containing transcription regulator protein 1; transcriptional co-activator with PDZ-binding motif (TA)Z; transcriptional co-activator with PDZ-binding motif (TAZ)

Invitrogen
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s5d
Invitrogen Wwtr1 antibody (Thermo Fisher Scientific, PA1-46190) was used in western blot on human samples at 1:1000 (fig s5d). Nat Commun (2017) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; loading ...; fig 3c
Cell Signaling Technology Wwtr1 antibody (Cell Signaling Technology, 4883S) was used in western blot on human samples (fig 3c). Cell Death Dis (2019) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 4g
Cell Signaling Technology Wwtr1 antibody (Cell Signaling, 4883) was used in western blot on mouse samples (fig 4g). Oncogene (2019) ncbi
rabbit polyclonal
  • immunoprecipitation; mouse; loading ...; fig 8e
  • western blot; mouse; loading ...; fig 8e
Cell Signaling Technology Wwtr1 antibody (Cell Signaling Technology, 4883S) was used in immunoprecipitation on mouse samples (fig 8e) and in western blot on mouse samples (fig 8e). J Clin Invest (2018) ncbi
rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology Wwtr1 antibody (Cell Signaling, 4883) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology Wwtr1 antibody (Cell Signaling, 4883) was used in western blot on human samples (fig 2a). Cancer Res (2017) ncbi
rabbit polyclonal
  • western blot; human; fig 1b
Cell Signaling Technology Wwtr1 antibody (Cell Signaling, 4883) was used in western blot on human samples (fig 1b). Nat Genet (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1b
In order to show a role for Hippo signaling in the epicardium in recruiting T regulatory cells post infarct, Cell Signaling Technology Wwtr1 antibody (Cell Signaling, 4883) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1b). J Clin Invest (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 6d
Cell Signaling Technology Wwtr1 antibody (Cell Signaling Technology, 4883) was used in western blot on mouse samples at 1:1000 (fig 6d). J Cell Biol (2017) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; mouse; loading ...; fig 8B
Cell Signaling Technology Wwtr1 antibody (Cell Signaling, 4883) was used in chromatin immunoprecipitation on mouse samples (fig 8B). elife (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4a
  • western blot; dog; loading ...; fig 6a
In order to propose that loss of Llgl1 results in epidermal growth factor receptor mislocalization and leads to pre-neoplastic changes, Cell Signaling Technology Wwtr1 antibody (cell signalling, 4883) was used in western blot on human samples (fig 4a) and in western blot on dog samples (fig 6a). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology Wwtr1 antibody (Cell signaling, 4883) was used in western blot on human samples (fig 1). J Biol Chem (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 7
  • western blot; mouse; fig 4
Cell Signaling Technology Wwtr1 antibody (Cell Signaling, 4883) was used in western blot on human samples (fig 7) and in western blot on mouse samples (fig 4). Proc Natl Acad Sci U S A (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 1
Cell Signaling Technology Wwtr1 antibody (Cell signaling, 4883) was used in western blot on mouse samples (fig 1). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology Wwtr1 antibody (Cell Signaling, 4883) was used in western blot on human samples at 1:1000 (fig 2). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3f
Cell Signaling Technology Wwtr1 antibody (Cell Signaling Technology, 4883) was used in western blot on mouse samples (fig 3f). J Biol Chem (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig s3
Cell Signaling Technology Wwtr1 antibody (Cell Signaling, 4883) was used in western blot on human samples at 1:1000 (fig s3). Nat Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology Wwtr1 antibody (Cell Signaling, 4883S) was used in western blot on human samples at 1:1000. Cell (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology Wwtr1 antibody (Cell Signaling Technology, 4883) was used in western blot on human samples at 1:1000 (fig 3). J Invest Dermatol (2014) ncbi
Articles Reviewed
  1. Gong L, Xiao Y, Xia F, Wu P, Zhao T, Xie S, et al. The mevalonate coordinates energy input and cell proliferation. Cell Death Dis. 2019;10:327 pubmed publisher
  2. Pan W, Moroishi T, Koo J, Guan K. Cell type-dependent function of LATS1/2 in cancer cell growth. Oncogene. 2019;38:2595-2610 pubmed publisher
  3. Li C, Xiao Y, Yang M, Su T, Sun X, Guo Q, et al. Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging. J Clin Invest. 2018;128:5251-5266 pubmed publisher
  4. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  5. Toloczko A, Guo F, Yuen H, Wen Q, Wood S, Ong Y, et al. Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway. Cancer Res. 2017;77:4921-4933 pubmed publisher
  6. van Groningen T, Koster J, Valentijn L, Zwijnenburg D, Akogul N, Hasselt N, et al. Neuroblastoma is composed of two super-enhancer-associated differentiation states. Nat Genet. 2017;49:1261-1266 pubmed publisher
  7. Nardone G, Oliver De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, et al. YAP regulates cell mechanics by controlling focal adhesion assembly. Nat Commun. 2017;8:15321 pubmed publisher
  8. Ramjee V, Li D, Manderfield L, Liu F, Engleka K, Aghajanian H, et al. Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction. J Clin Invest. 2017;127:899-911 pubmed publisher
  9. Mindos T, Dun X, North K, Doddrell R, Schulz A, Edwards P, et al. Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity. J Cell Biol. 2017;216:495-510 pubmed publisher
  10. Grove M, Kim H, Santerre M, Krupka A, Han S, Zhai J, et al. YAP/TAZ initiate and maintain Schwann cell myelination. elife. 2017;6: pubmed publisher
  11. Greenwood E, Maisel S, Ebertz D, Russ A, Pandey R, SCHROEDER J. Llgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration. Oncotarget. 2016;7:60776-60792 pubmed publisher
  12. Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;291:14761-72 pubmed publisher
  13. Nishio M, Sugimachi K, Goto H, Wang J, Morikawa T, Miyachi Y, et al. Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice. Proc Natl Acad Sci U S A. 2016;113:E71-80 pubmed publisher
  14. Sun J, Chen X, Zhang L, Wang J, Diehn M. Yap1 promotes the survival and self-renewal of breast tumor initiating cells via inhibiting Smad3 signaling. Oncotarget. 2016;7:9692-706 pubmed publisher
  15. Slemmons K, Crose L, Rudzinski E, Bentley R, Linardic C. Role of the YAP Oncoprotein in Priming Ras-Driven Rhabdomyosarcoma. PLoS ONE. 2015;10:e0140781 pubmed publisher
  16. Finch Edmondson M, Strauss R, Passman A, Sudol M, Yeoh G, Callus B. TAZ Protein Accumulation Is Negatively Regulated by YAP Abundance in Mammalian Cells. J Biol Chem. 2015;290:27928-38 pubmed publisher
  17. Mo J, Meng Z, Kim Y, Park H, Hansen C, Kim S, et al. Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway. Nat Cell Biol. 2015;17:500-10 pubmed publisher
  18. Mori M, Triboulet R, Mohseni M, Schlegelmilch K, Shrestha K, Camargo F, et al. Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer. Cell. 2014;156:893-906 pubmed publisher
  19. Nallet Staub F, Marsaud V, Li L, Gilbert C, Dodier S, Bataille V, et al. Pro-invasive activity of the Hippo pathway effectors YAP and TAZ in cutaneous melanoma. J Invest Dermatol. 2014;134:123-132 pubmed publisher