This is a Validated Antibody Database (VAD) review about rat Wdr5, based on 14 published articles (read how Labome selects the articles), using Wdr5 antibody in all methods. It is aimed to help Labome visitors find the most suited Wdr5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Wdr5 synonym: WD repeat-containing protein 5; WD repeat-containing protein 5-like

Bethyl
rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig 6a
  • western blot; human; loading ...; fig 1e
Bethyl Wdr5 antibody (Bethyl Laboratories, A302-430A) was used in chromatin immunoprecipitation on human samples (fig 6a) and in western blot on human samples (fig 1e). Biol Open (2016) ncbi
rabbit polyclonal
  • western blot; human; fig s3
Bethyl Wdr5 antibody (Bethyl, A302-430A) was used in western blot on human samples (fig s3). Genome Biol (2016) ncbi
rabbit polyclonal
  • immunoprecipitation; mouse; fig 4
  • western blot; human; fig 4
Bethyl Wdr5 antibody (Bethyl Laboratories, A302-430A) was used in immunoprecipitation on mouse samples (fig 4) and in western blot on human samples (fig 4). Mol Cell Proteomics (2016) ncbi
rabbit polyclonal
  • immunoprecipitation; human; fig s3
  • western blot; human; fig 2a
In order to test if lncRNA SRA interacts with TrxG or PRC2, Bethyl Wdr5 antibody (Bethyl Laboratories, A302-430A) was used in immunoprecipitation on human samples (fig s3) and in western blot on human samples (fig 2a). PLoS Genet (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 6
Bethyl Wdr5 antibody (Bethyl Laboratories, A302-430A) was used in western blot on human samples (fig 6). Mol Biosyst (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:3500
Bethyl Wdr5 antibody (Bethyl, A302-430A) was used in western blot on human samples at 1:3500. J Biol Chem (2015) ncbi
rabbit polyclonal
  • western blot; human
Bethyl Wdr5 antibody (Bethyl, A302-430A) was used in western blot on human samples . Oncotarget (2014) ncbi
Abcam
rabbit monoclonal (EPR11350)
  • western blot; human; fig 5d
Abcam Wdr5 antibody (Abcam, ab178410) was used in western blot on human samples (fig 5d). Cell (2018) ncbi
rabbit polyclonal
  • western blot; human; 1:2000
Abcam Wdr5 antibody (Abcam, ab22512) was used in western blot on human samples at 1:2000. J Biol Chem (2015) ncbi
rabbit polyclonal
  • western blot; human
In order to examine the relation between cullin 4B variants and intellectual disability, Abcam Wdr5 antibody (Abcam, ab22512) was used in western blot on human samples . Hum Mutat (2015) ncbi
rabbit polyclonal
  • western blot; human
Abcam Wdr5 antibody (Abacm, ab22512) was used in western blot on human samples . J Biol Chem (2013) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; mouse
  • immunoprecipitation; mouse
  • western blot; mouse
Abcam Wdr5 antibody (Abcam, ab22512-100) was used in chromatin immunoprecipitation on mouse samples , in immunoprecipitation on mouse samples and in western blot on mouse samples . EMBO J (2011) ncbi
Santa Cruz Biotechnology
mouse monoclonal (G-9)
  • western blot; human; fig 6c
Santa Cruz Biotechnology Wdr5 antibody (Santa Cruz, sc-393080) was used in western blot on human samples (fig 6c). FEBS J (2018) ncbi
Proteintech Group
rabbit polyclonal
  • immunocytochemistry; mouse; 1:100
  • western blot; mouse; 1:2000
Proteintech Group Wdr5 antibody (ProteinTech, 15544-1-AP) was used in immunocytochemistry on mouse samples at 1:100 and in western blot on mouse samples at 1:2000. Proc Natl Acad Sci U S A (2012) ncbi
Articles Reviewed
  1. Hoshii T, Cifani P, Feng Z, Huang C, Koche R, Chen C, et al. A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response. Cell. 2018;172:1007-1021.e17 pubmed publisher
  2. Bieluszewska A, Weglewska M, Bieluszewski T, Lesniewicz K, Poreba E. PKA-binding domain of AKAP8 is essential for direct interaction with DPY30 protein. FEBS J. 2018;285:947-964 pubmed publisher
  3. Lu F, Wu X, Yin F, Chia Fang Lee C, Yu M, Mihaylov I, et al. Regulation of DNA replication and chromosomal polyploidy by the MLL-WDR5-RBBP5 methyltransferases. Biol Open. 2016;5:1449-1460 pubmed publisher
  4. G Hendrickson D, Kelley D, Tenen D, BERNSTEIN B, Rinn J. Widespread RNA binding by chromatin-associated proteins. Genome Biol. 2016;17:28 pubmed publisher
  5. Bode D, Yu L, Tate P, Pardo M, Choudhary J. Characterization of Two Distinct Nucleosome Remodeling and Deacetylase (NuRD) Complex Assemblies in Embryonic Stem Cells. Mol Cell Proteomics. 2016;15:878-91 pubmed publisher
  6. Wongtrakoongate P, Riddick G, Fucharoen S, Felsenfeld G. Association of the Long Non-coding RNA Steroid Receptor RNA Activator (SRA) with TrxG and PRC2 Complexes. PLoS Genet. 2015;11:e1005615 pubmed publisher
  7. Qi D, Wang Q, Li H, Zhang T, Lan R, Kwong D, et al. SILAC-based quantitative proteomics identified lysosome as a fast response target to PDT agent Gd-N induced oxidative stress in human ovarian cancer IGROV1 cells. Mol Biosyst. 2015;11:3059-67 pubmed publisher
  8. Bailey J, Fields A, Cheng K, Lee A, Wagenaar E, Lagrois R, et al. WD repeat-containing protein 5 (WDR5) localizes to the midbody and regulates abscission. J Biol Chem. 2015;290:8987-9001 pubmed publisher
  9. Shinsky S, Monteith K, Viggiano S, Cosgrove M. Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation. J Biol Chem. 2015;290:6361-75 pubmed publisher
  10. Vulto van Silfhout A, Nakagawa T, Bahi Buisson N, Haas S, Hu H, Bienek M, et al. Variants in CUL4B are associated with cerebral malformations. Hum Mutat. 2015;36:106-17 pubmed publisher
  11. Putiri E, Tiedemann R, Liu C, Choi J, Robertson K. Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome. Oncotarget. 2014;5:6338-52 pubmed
  12. Zhou P, Wang Z, Yuan X, Zhou C, Liu L, Wan X, et al. Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle progression and E2F1-responsive gene expression via association with host cell factor-1 (HCF-1). J Biol Chem. 2013;288:17532-43 pubmed publisher
  13. Ma P, Pan H, Montgomery R, Olson E, Schultz R. Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development. Proc Natl Acad Sci U S A. 2012;109:E481-9 pubmed publisher
  14. Xie L, Pelz C, Wang W, Bashar A, Varlamova O, Shadle S, et al. KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription. EMBO J. 2011;30:1473-84 pubmed publisher