This is a Validated Antibody Database (VAD) review about rat Ucp2, based on 6 published articles (read how Labome selects the articles), using Ucp2 antibody in all methods. It is aimed to help Labome visitors find the most suited Ucp2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ucp2 synonym: mitochondrial uncoupling protein 2; UCP 2; Uncoupling protein 2, mitochondrial; solute carrier family 25 member 8; uncoupling protein 2 (mitochondrial, proton carrier)

Knockout validation
EMD Millipore
rabbit polyclonal
  • immunohistochemistry knockout validation; mouse; 1:100; loading ...; fig 1a
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1a
EMD Millipore Ucp2 antibody (Millipore, 662047) was used in immunohistochemistry knockout validation on mouse samples at 1:100 (fig 1a) and in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 1a). J Neurosci (2019) ncbi
Santa Cruz Biotechnology
mouse monoclonal (G-6)
  • western blot; mouse; fig 6
Santa Cruz Biotechnology Ucp2 antibody (Santa Cruz, sc-390189) was used in western blot on mouse samples (fig 6). Int J Mol Med (2016) ncbi
mouse monoclonal (G-6)
  • western blot; rat; 1:500; fig 4
Santa Cruz Biotechnology Ucp2 antibody (Santa Cruz, sc-390189) was used in western blot on rat samples at 1:500 (fig 4). Mol Med Rep (2015) ncbi
Abcam
mouse polyclonal
  • western blot; human; 1:500; fig 2
Abcam Ucp2 antibody (Abcam, ab67241) was used in western blot on human samples at 1:500 (fig 2). Int J Mol Med (2016) ncbi
Proteintech Group
rabbit polyclonal
  • immunocytochemistry; human
  • western blot; human; fig 2b
In order to study the inhibition of tumor growth caused by mitochondrial dysfunction in the epithelial cancer cell compartment, Proteintech Group Ucp2 antibody (Proteintech, 11081-1-AP) was used in immunocytochemistry on human samples and in western blot on human samples (fig 2b). Cell Cycle (2013) ncbi
EMD Millipore
rabbit polyclonal
  • immunohistochemistry knockout validation; mouse; 1:100; loading ...; fig 1a
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1a
EMD Millipore Ucp2 antibody (Millipore, 662047) was used in immunohistochemistry knockout validation on mouse samples at 1:100 (fig 1a) and in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 1a). J Neurosci (2019) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 2c
In order to determine the protective effects of pepsin-digested chicken liver hydrolysates against chronic alcohol consumption, EMD Millipore Ucp2 antibody (Calbiochem, 662047) was used in western blot on mouse samples (fig 2c). Food Funct (2017) ncbi
Articles Reviewed
  1. Hass D, Barnstable C. Mitochondrial Uncoupling Protein 2 Knockout Promotes Mitophagy to Decrease Retinal Ganglion Cell Death in a Mouse Model of Glaucoma. J Neurosci. 2019;: pubmed publisher
  2. Lin Y, Tai S, Chen J, Chou C, Fu S, Chen Y. Ameliorative effects of pepsin-digested chicken liver hydrolysates on development of alcoholic fatty livers in mice. Food Funct. 2017;8:1763-1774 pubmed publisher
  3. Shinohara S, Gu Y, Yang Y, Furuta Y, Tanaka M, Yue X, et al. Ethanol extracts of chickpeas alter the total lipid content and expression levels of genes related to fatty acid metabolism in mouse 3T3-L1 adipocytes. Int J Mol Med. 2016;38:574-84 pubmed publisher
  4. He Y, Luan Z, Fu X, Xu X. Overexpression of uncoupling protein 2 inhibits the high glucose-induced apoptosis of human umbilical vein endothelial cells. Int J Mol Med. 2016;37:631-8 pubmed publisher
  5. Li P, Luo S, Pan C, Cheng X. Modulation of fatty acid metabolism is involved in the alleviation of isoproterenol-induced rat heart failure by fenofibrate. Mol Med Rep. 2015;12:7899-906 pubmed publisher
  6. Sánchez Alvarez R, Martinez Outschoorn U, Lamb R, Hulit J, Howell A, Gandara R, et al. Mitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin. Cell Cycle. 2013;12:172-82 pubmed publisher