This is a Validated Antibody Database (VAD) review about rat Tpx2, based on 7 published articles (read how Labome selects the articles), using Tpx2 antibody in all methods. It is aimed to help Labome visitors find the most suited Tpx2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tpx2 synonym: targeting protein for Xklp2; TPX2, microtubule-associated protein homolog; TPX2, microtubule-associated, homolog

Novus Biologicals
rabbit polyclonal
  • immunocytochemistry; human; 1:1000; loading ...; fig 6a
  • western blot; human; loading ...; fig 6g
Novus Biologicals Tpx2 antibody (Novus, mb500179) was used in immunocytochemistry on human samples at 1:1000 (fig 6a) and in western blot on human samples (fig 6g). Mol Cancer Res (2018) ncbi
rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 3
Novus Biologicals Tpx2 antibody (Acris Antibodies GmbH, NB500-179) was used in immunocytochemistry on human samples (fig 3). Int J Oncol (2017) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:1000; fig 4
In order to elucidate the spindle proteome that is clathirin-dependent, Novus Biologicals Tpx2 antibody (Novus Biologicals, NB500-179) was used in immunocytochemistry on human samples at 1:1000 (fig 4). Mol Cell Proteomics (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig s3
In order to identify microtubule-associated proteins that interact with ch-TOG to regulate bipolar spindle assembly in human cells, Novus Biologicals Tpx2 antibody (Novus, NB500-179) was used in western blot on human samples at 1:1000 (fig s3). Sci Rep (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-5)
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 2d
Santa Cruz Biotechnology Tpx2 antibody (Santa Cruz, sc-376812) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 2d). World J Surg Oncol (2017) ncbi
Abcam
mouse monoclonal (18D5-1)
  • western blot; human; loading ...; fig 6b
Abcam Tpx2 antibody (Abcam, ab32795) was used in western blot on human samples (fig 6b). J Cell Biol (2015) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; mouse; fig 7
Proteintech Group Tpx2 antibody (Proteintech, 11741-1-AP) was used in western blot on mouse samples (fig 7). J Cell Sci (2015) ncbi
Articles Reviewed
  1. Chu T, Connell M, Zhou L, He Z, Won J, Chen H, et al. Cell Cycle-Dependent Tumor Engraftment and Migration Are Enabled by Aurora-A. Mol Cancer Res. 2018;16:16-31 pubmed publisher
  2. Schneider M, Christopoulos P, Muley T, Warth A, Klingmueller U, Thomas M, et al. AURKA, DLGAP5, TPX2, KIF11 and CKAP5: Five specific mitosis-associated genes correlate with poor prognosis for non-small cell lung cancer patients. Int J Oncol. 2017;50:365-372 pubmed publisher
  3. Tomii C, Inokuchi M, Takagi Y, Ishikawa T, Otsuki S, Uetake H, et al. TPX2 expression is associated with poor survival in gastric cancer. World J Surg Oncol. 2017;15:14 pubmed publisher
  4. Rao S, Flores Rodriguez N, Page S, Wong C, Robinson P, Chircop M. The Clathrin-dependent Spindle Proteome. Mol Cell Proteomics. 2016;15:2537-53 pubmed publisher
  5. Hu M, Wang Z, Teng Y, Jiang Z, Ma X, Hou N, et al. Loss of protein phosphatase 6 in oocytes causes failure of meiosis II exit and impaired female fertility. J Cell Sci. 2015;128:3769-80 pubmed publisher
  6. Yan K, Li L, Wang X, Hong R, Zhang Y, Yang H, et al. The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells. J Cell Biol. 2015;210:209-24 pubmed publisher
  7. Barr A, Bakal C. A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. Sci Rep. 2015;5:10564 pubmed publisher