This is a Validated Antibody Database (VAD) review about rat Tpl 2, based on 2 published articles (read how Labome selects the articles), using Tpl 2 antibody in all methods. It is aimed to help Labome visitors find the most suited Tpl 2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tpl 2 synonym: D17TPL2; Tpl-2; Tpl2; mitogen-activated protein kinase kinase kinase 8; serine/threonine kinase (Tpl-2); tumor progression locus 2

Cell Signaling Technology
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 4d
In order to identify and study roles for MAP3K8 in high-grade serous ovarian carcinomas, Cell Signaling Technology Tpl 2 antibody (Cell Signalling, 4491) was used in western blot on human samples at 1:1000 (fig 4d). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology Tpl 2 antibody (Cell Signaling Technology, 4491) was used in western blot on human samples . Carcinogenesis (2014) ncbi
Articles Reviewed
  1. Gruosso T, Garnier C, Abélanet S, Kieffer Y, Lemesre V, Bellanger D, et al. MAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomas. Nat Commun. 2015;6:8583 pubmed publisher
  2. Kim K, Kim G, Kim J, Yun H, Lim S, Choi H. Interleukin-22 promotes epithelial cell transformation and breast tumorigenesis via MAP3K8 activation. Carcinogenesis. 2014;35:1352-61 pubmed publisher