This is a Validated Antibody Database (VAD) review about rat Tph2, based on 19 published articles (read how Labome selects the articles), using Tph2 antibody in all methods. It is aimed to help Labome visitors find the most suited Tph2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tph2 synonym: Ntph

Knockout validation
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig e6d
Abcam Tph2 antibody (Abcam, ab111828) was used in western blot knockout validation on mouse samples at 1:1000 (fig e6d). Nature (2019) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1b
Invitrogen Tph2 antibody (Thermo Fisher, PA1-778) was used in immunohistochemistry - frozen section on mouse samples (fig 1b). Front Mol Neurosci (2021) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:500; loading ...
In order to assess how plasticity in the midbrain dorsal raphe nucleus affects maternal behavior, Invitrogen Tph2 antibody (Thermo Scientific, PA1-778) was used in western blot on rat samples at 1:500. Psychoneuroendocrinology (2017) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; fig 7.8
In order to study how variability in maternal care received among female rat siblings affects the siblings' later emotional and maternal behaviors, Invitrogen Tph2 antibody (Thermo Fisher Scientific, #PA1-778) was used in western blot on rat samples at 1:1000 (fig 7.8). Horm Behav (2016) ncbi
domestic rabbit polyclonal
In order to study hypoxia-induced chemosensory activity in the carotid body, Invitrogen Tph2 antibody (thermo, pa1-778) was used . Brain Res (2015) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; loading ...; fig 5d
Abcam Tph2 antibody (Abcam, ab111828) was used in immunohistochemistry - frozen section on mouse samples (fig 5d). Sci Rep (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:500; fig 3d
Abcam Tph2 antibody (Abcam, ab111828) was used in immunohistochemistry on mouse samples at 1:500 (fig 3d). J Neurosci (2020) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig e6d
Abcam Tph2 antibody (Abcam, ab111828) was used in western blot knockout validation on mouse samples at 1:1000 (fig e6d). Nature (2019) ncbi
Novus Biologicals
domestic rabbit polyclonal (711-66)
  • immunocytochemistry; human; 1:2000; loading ...; fig 4a
Novus Biologicals Tph2 antibody (Novus, NB100-74555) was used in immunocytochemistry on human samples at 1:2000 (fig 4a). J Neural Transm (Vienna) (2021) ncbi
domestic rabbit polyclonal (711-66)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4a
Novus Biologicals Tph2 antibody (Novus, NB100-74555) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 4a). Biomolecules (2020) ncbi
domestic rabbit polyclonal (711-66)
  • immunohistochemistry; mouse; 1:500; loading ...; fig 6b
In order to develop methods to identify the major projections to the mesolimbic dopamine circuit from the lateral hypothalamus and dorsal raphe nucleus, Novus Biologicals Tph2 antibody (Novus Biologicals, NB100-74555) was used in immunohistochemistry on mouse samples at 1:500 (fig 6b). J Neurosci (2017) ncbi
MilliporeSigma
mouse monoclonal (CL2990)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4g, 4h, 4i
MilliporeSigma Tph2 antibody (Sigma, AMAB91108) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 4g, 4h, 4i). Transl Psychiatry (2021) ncbi
mouse monoclonal (WH-3)
  • immunohistochemistry; mouse; loading ...; fig 2b
MilliporeSigma Tph2 antibody (MilliporeSigma, T0678) was used in immunohistochemistry on mouse samples (fig 2b). elife (2020) ncbi
mouse monoclonal (WH-3)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 1ii
MilliporeSigma Tph2 antibody (Sigma-Aldrich, T0678) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 1ii). elife (2020) ncbi
mouse monoclonal (WH-3)
  • immunohistochemistry; rat; 1:400; fig 1g1
MilliporeSigma Tph2 antibody (Sigma, T0678) was used in immunohistochemistry on rat samples at 1:400 (fig 1g1). Alzheimers Res Ther (2019) ncbi
mouse monoclonal (WH-3)
  • immunohistochemistry; rat; 1:1000; loading ...; fig 5b
In order to study the role of neuromedin U in drugs of abuse and visualize its receptor, MilliporeSigma Tph2 antibody (Sigma, T0678) was used in immunohistochemistry on rat samples at 1:1000 (fig 5b). Biol Psychiatry (2016) ncbi
mouse monoclonal (WH-3)
  • immunohistochemistry; mouse; 1:3000; loading ...; tbl 1
In order to determine the neuron composition of the median raphe region, MilliporeSigma Tph2 antibody (Sigma, T0678) was used in immunohistochemistry on mouse samples at 1:3000 (tbl 1). Brain Struct Funct (2017) ncbi
mouse monoclonal (WH-3)
  • immunohistochemistry - frozen section; rat; 1:1000; fig 4
MilliporeSigma Tph2 antibody (Sigma, T0678) was used in immunohistochemistry - frozen section on rat samples at 1:1000 (fig 4). Front Neurosci (2015) ncbi
mouse monoclonal (WH-3)
  • immunocytochemistry; mouse; 1:500; fig 4
MilliporeSigma Tph2 antibody (Sigma, T0678) was used in immunocytochemistry on mouse samples at 1:500 (fig 4). J Neurosci (2015) ncbi
mouse monoclonal (WH-3)
  • immunohistochemistry - frozen section; mouse; 1:400
In order to study the firing of dorsal raphe serotonergic neurons, MilliporeSigma Tph2 antibody (Sigma-Aldrich, T0678) was used in immunohistochemistry - frozen section on mouse samples at 1:400. PLoS ONE (2014) ncbi
Articles Reviewed
  1. Tesoro Cruz E, Manuel Apolinar L, Oviedo N, Orozco Suarez S, Crespo Ramírez M, Bekker Mendez V, et al. Increase of 5-HT levels is induced both in mouse brain and HEK-293 cells following their exposure to a non-viral tryptophan hydroxylase construct. Transl Psychiatry. 2021;11:515 pubmed publisher
  2. Sahu M, Pazos Boubeta Y, Steinzeig A, Kaurinkoski K, Palmisano M, Borowecki O, et al. Depletion of TrkB Receptors From Adult Serotonergic Neurons Increases Brain Serotonin Levels, Enhances Energy Metabolism and Impairs Learning and Memory. Front Mol Neurosci. 2021;14:616178 pubmed publisher
  3. Yoo H, Yang S, Kim J, Yang E, Park H, Lee S, et al. Down-regulation of habenular calcium-dependent secretion activator 2 induces despair-like behavior. Sci Rep. 2021;11:3700 pubmed publisher
  4. Jansch C, Ziegler G, Forero A, Gredy S, W xe4 ldchen S, Vitale M, et al. Serotonin-specific neurons differentiated from human iPSCs form distinct subtypes with synaptic protein assembly. J Neural Transm (Vienna). 2021;128:225-241 pubmed publisher
  5. Uchida S, Soya S, Saito Y, Hirano A, Koga K, Tsuda M, et al. A discrete glycinergic neuronal population in the ventromedial medulla that induces muscle atonia during REM sleep and cataplexy in mice. J Neurosci. 2020;: pubmed publisher
  6. Hung C, Ono D, Kilduff T, Yamanaka A. Dual orexin and MCH neuron-ablated mice display severe sleep attacks and cataplexy. elife. 2020;9: pubmed publisher
  7. Azimi Z, Barzan R, Spoida K, Surdin T, Wollenweber P, Mark M, et al. Separable gain control of ongoing and evoked activity in the visual cortex by serotonergic input. elife. 2020;9: pubmed publisher
  8. Lee J, Jeon Y, Park S, Son C. An Adrenalectomy Mouse Model Reflecting Clinical Features for Chronic Fatigue Syndrome. Biomolecules. 2020;10: pubmed publisher
  9. Ghosh A, Torraville S, Mukherjee B, Walling S, Martin G, Harley C, et al. An experimental model of Braak's pretangle proposal for the origin of Alzheimer's disease: the role of locus coeruleus in early symptom development. Alzheimers Res Ther. 2019;11:59 pubmed publisher
  10. Farrelly L, Thompson R, Zhao S, Lepack A, Lyu Y, Bhanu N, et al. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. 2019;567:535-539 pubmed publisher
  11. Pomeranz L, Ekstrand M, Latcha K, Smith G, Enquist L, Friedman J. Gene Expression Profiling with Cre-Conditional Pseudorabies Virus Reveals a Subset of Midbrain Neurons That Participate in Reward Circuitry. J Neurosci. 2017;37:4128-4144 pubmed publisher
  12. Holschbach M, Lonstein J. Motherhood and infant contact regulate neuroplasticity in the serotonergic midbrain dorsal raphe. Psychoneuroendocrinology. 2017;76:97-106 pubmed publisher
  13. Kasper J, McCue D, Milton A, Szwed A, Sampson C, Huang M, et al. Gamma-Aminobutyric Acidergic Projections From the Dorsal Raphe to the Nucleus Accumbens Are Regulated by Neuromedin U. Biol Psychiatry. 2016;80:878-887 pubmed publisher
  14. Sos K, Mayer M, Cserép C, Takács F, Szonyi A, Freund T, et al. Cellular architecture and transmitter phenotypes of neurons of the mouse median raphe region. Brain Struct Funct. 2017;222:287-299 pubmed publisher
  15. Pomrenze M, Millan E, Hopf F, Keiflin R, Maiya R, Blasio A, et al. A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits. Front Neurosci. 2015;9:487 pubmed publisher
  16. Ehrich J, Messinger D, Knakal C, Kuhar J, Schattauer S, Bruchas M, et al. Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons. J Neurosci. 2015;35:12917-31 pubmed publisher
  17. Ragan C, Harding K, Lonstein J. Associations among within-litter differences in early mothering received and later emotional behaviors, mothering, and cortical tryptophan hydroxylase-2 expression in female laboratory rats. Horm Behav. 2016;77:62-71 pubmed publisher
  18. Yokoyama T, Nakamuta N, Kusakabe T, Yamamoto Y. Sympathetic regulation of vascular tone via noradrenaline and serotonin in the rat carotid body as revealed by intracellular calcium imaging. Brain Res. 2015;1596:126-35 pubmed publisher
  19. Dugué G, Lorincz M, Lottem E, Audero E, Matias S, Correia P, et al. Optogenetic recruitment of dorsal raphe serotonergic neurons acutely decreases mechanosensory responsivity in behaving mice. PLoS ONE. 2014;9:e105941 pubmed publisher